Columbus, OH

The phase 3 SOHO-02 trial has enrolled its first patient with advanced non–small cell lung cancer harboring activating HER2 mutations. The first patient with advanced non–small cell lung cancer (NSCLC) with a tumor that has activating HER2 mutations has been enrolled in the phase 3 SOHO-02 trial (NCT06452277) of frontline treatment with BAY 2927088.1.

Enrollment Begins in Phase 3 SOHO-02 Trial of BAY 2927088 in NSCLC

Coffee County, GA

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Daily Coffee Press

Last week, two individuals from Coffee County were charged with trafficking methamphetamine following a search at a residence on Willacoochee Highway. On August 13, detectives with the Coffee County Drug Unit conducted an operation involving Charles Black, which led to a search of his residence on Willacoochee Highway. According to the report, Black left his residence before the warrant was served and was subsequently detained.

Two Charged with Trafficking Methamphetamine After Search in Coffee County

Solly Chedid, MD, provides clinical insights on quality-of-life assessment practices for patients with MDS. Case: Frontline Use of Erythroid Maturating Agent (EMA): Luspatercept. Clinical Presentation:. 70-year-old man diagnosed 6 months ago with LR-MDS with multilineage dysplasia - moderate anemia (Hb 11.2) and thrombocytosis (PLT 500,000 μl) SF3B1 mutation positive.

Assessing QoL in MDS Patients

Los Angeles, CA

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Herbie J Pilato

Adam Rich was born on October 12, 1968, lived a troubled life, and died on January 7, 2023, at only 54 years old. This is his story. He lived in the Granada Hills area of Los Angeles with his parents and younger brother. The Rich family resided for a time in Florida where Adam studied acting at the local gym.

A Look Back at the Tragic Life and Death of Former Child Star Adam Rich (TV's 'Eight is Enough')

Colorado State

David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Elizabeth Franzmann, MD, discusses findings of a study exploring a novel method of testing recurrence of head and neck cancer. A study sought to evaluate the effectiveness of soluble CD44 and total protein (TP) as biomarkers for monitoring head and neck cancer recurrence. Here, patients were monitored using a point-of-care (POC) salivary test and laboratory-based assays for CD44 and TP levels.

Convenient Saliva Test Could Predict Head and Neck Cancer Recurrence

The Lens

This year’s area of low oxygen in the Gulf of Mexico is larger than average, the National Oceanic and Atmospheric Administration (NOAA) announced on Thursday. The “dead zone” is approximately 6,705 square miles , as measured last week. Within NOAA’s 38 years of measuring the dead zone, this year’s assessment marks the 12th-largest area of low to no oxygen, which can kill fish and marine life.

Gulf ‘dead zone’ larger than average, larger than expected for 2024, scientists announce

Apache Junction, AZ

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Suzy Jacobson Cherry

When I studied Anthropology in college, I learned that teeth have been indicators of economic status just about forever. Archaeologists look at the teeth in ancient skeletons and know who the rich were based on their tooth decay. During the Renaissance period, it became fashionable for women to blacken their teeth to look like they were better off than they were, because the royals and aristocrats, who could afford sugar and sweets, had more rotten and missing teeth than the poor.

Opinion: Stop Stereotyping Bad Teeth as a Sign of Drug Addiction

Declutterbuzz

Declutter your brain first. In my years of helping people declutter their homes and lives, I’ve come to understand a truth many overlook - clutter isn’t just about the stuff around you—it’s deeply connected to the clutter in your mind.

Simple Ways To Declutter Your Brain For Better Focus

Alabama State

Jacksonville, FL

Jacksonville Today

On Sunday, a year after a Clay County man drove to their neighborhood to target Black people, the three victims of the mass shooting in Northwest Jacksonville were remembered by their family, friends, loved ones and the wider community.

Soil collection ceremony marks 1-year anniversary of Dollar General shooting

The TruSight Oncology Comprehensive test has been approved by the FDA as a companion diagnostic for NTRK-fusion positive solid tumors and RET-fusion positive non–small cell lung cancer. The TruSight Oncology (TSO) Comprehensive test has received approval from the FDA as a companion diagnostic (CDx) for 2 important cancer indications.

TruSight Oncology Test Receives FDA Approval for NTRK and RET Fusion Cancers

Gillian May

I’m a former nurse and recovering alcoholic, and I’ve been concerned by the lack of health education given to the general public about the dangers of mixing alcohol with certain medications. The common practice is to place warnings on medications that they should not be combined with alcohol. Although some doctors will provide warnings and some education, they often don’t because education takes up a lot of time in a busy healthcare environment. Plus, many doctors underestimate the ability of patients to retain education. Lastly, discussing this may prompt people to stop taking their vital medications so it becomes a risk/benefit issue.

Opinion: Why You Shouldn’t Mix These Medications With Alcohol

Kenneth Shain, MD, PhD, discusses the rationale for giving chimeric antigen receptor (CAR) T-cell therapy in earlier lines of therapy for relapsed/refractory (R/R) multiple myeloma. Kenneth Shain, MD, PhD, associate member in the Malignant Hematology program and director of the Myeloma Research Center at Moffitt Cancer Center, and assistant professor...

Efficacy and Treatment-Free Interval Support Earlier Use of CAR T in R/R Myeloma

Denver, CO

Former drug users and advocates for people who use drugs asked the Denver City Council Monday to act and open a safe injection center for drug users. Several people spoke during the public comment period. The council adopted a proclamation supporting drug users later in the meeting. Kevin Flynn was absent.

Denver drug users, advocates decry overdose, ask for injection center

Jeff Sharman, MD, discusses findings from the ELEVATE-TN trial of acalabrutinib with or without obinutuzumab for the treatment of patients with treatment-naive chronic lymphocytic leukemia. Jeff Sharman, MD, medical director of hematology research at US Oncology, discusses findings from the ELEVATE-TN trial (NCT02475681) of acalabrutinib (Calquence) with or without obinutuzumab...

Sharman Discusses ELEVATE-TN Trial Findings in CLL

Houston, TX

During a Case-Based Roundtable® event, Hussein A. Tawbi, MD, PhD, and participants considered nivolumab/ipilimumab and nivolumab/relatlimab as options for a patient with metastatic melanoma in the first article of a 2-part series. Hussein A. Tawbi, MD, PhD (Moderator) Professor. Deputy Chair. Director of Personalized Cancer Therapy. Department of Melanoma...

Nivolumab Combinations Debated for a Patient With Metastatic Melanoma

People report feeling overwhelmed when tasked with Decluttering. Whether it's the lack of time, dealing with chronic illness, or managing ADHD, these obstacles can seem impossible. Today, we're going to make your decluttering process simpler by using the guide How To Overcome Common Obstacles To Decluttering.

How To Overcome Common Obstacles To Decluttering

It's been four decades since Emmy-nominated actor Lloyd Haynes died of lung cancer at only 52 years old. Best known for his compassionate performance as history teacher Pete Dixon on television's groundbreaking, academic-geared dramedy, Room 222 (ABC, 1969-1974), Haynes was beloved by his fans, family, friends and colleagues alike. This is his story.

In Memory of 'Room 222' TV Actor Lloyd Haynes: 4 Decades After His Tragic Death From Lung Cancer

Clutter, can and often does, creep up on us because decluttering is an ongoing process. This makes our homes feel more like chaotic storage units than serene sanctuaries. Keep reading to learn how to avoid making decluttering mistakes.

How To Avoid Making Common Decluttering Mistakes

New Jersey State

Lawrence Township, NJ

Morristown Minute

NEW JERSEY - In a significant ruling, the New Jersey Supreme Court has permanently removed Lewis J. Korngut from his position as a Municipal Court Judge. The decision, finalized on July 24, 2024, follows an extensive investigation by the Advisory Committee on Judicial Conduct (ACJC) into numerous allegations of unethical behavior.

NJ Judge Permanently Removed for Unethical Conduct

NewsBreak

HEROEX-1 Trial Begins for HER2-Selective Inhibitor NVL-330 in NSCLC

The first pretreated patient with HER2-altered non–small cell lung cancer was dosed with NVL-330, a novel HER2-selective inhibitor, in the HEROEX-1 trial. The phase 1a/1b HEROEX-1...

HEROEX-1 Trial Begins for HER2-Selective Inhibitor NVL-330 in NSCLC

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