Reuters

(Reuters) - Servier Pharmaceuticals said on Tuesday the U.S. Food and Drug administration has approved the French drugmaker's treatment for a type of brain tumor, making it the first drug to get a U.S. approval for the condition.

US FDA approves Servier's brain tumor treatment

Servier has expanded its IDH drug armamentarium with the FDA approval for an IDH1/2 dual inhibitor. The approval represents the first major treatment advance in low-grade brain cancer in more than two decades. The new FDA approval is for Servier’s Voranigo, or vorasidenib, for adult and children ages 12 and...

Servier snags FDA approval for Voranigo, the first targeted therapy for a common type of brain tumor

Cancer Health

In 2006, Diana Lindsay, who had never so much as held a cigarette, was diagnosed with stage 4 lung cancer. It had metastasized to both lungs, her brain and lymph nodes. Keith Eaton, MD, PhD, clinical director of thoracic, head and neck medical oncology at Fred Hutch Cancer Center, told her that a typical patient in this situation would have about nine months to live. But he also observed that she seemed remarkably strong and vital. “He said, ‘You don’t look like my normal lung cancer patient,’” said Lindsay, who had just returned from a business trip to Europe. She was 54 at the time. “He didn’t want to take away the health I had for the limited time I had to live.”

20 Years Since an EGFR Discovery, a Woman With Stage IV Lung Cancer Is Thriving

The FDA on Thursday signed off on Citius Pharmaceuticals’ Lymphir (denileukin diftitox-cxdl) for the treatment of patients with relapsed or refractory cutaneous T cell lymphoma, who have undergone at least one prior line of systemic therapy. Lymphir is Citius’ first FDA-approved product and currently the only treatment for cutaneous...

Citius Scores FDA Approval in Cutaneous T Cell Lymphoma

Merck announced Thursday that it is ending a late-stage trial of its blockbuster Keytruda, anti-TIGIT antibody vibostolimab and chemotherapy in the first line treatment of extensive-stage small cell lung cancer, after a recommendation from an independent data monitoring committee. The Phase III KeyVibe-008 trial compared the anti-TIGIT, Keytruda and chemo...

Merck Halts Phase III Trial of Keytruda, Anti-TIGIT Combo in Small Cell Lung Cancer

Interesting Engineering

Patients experienced a significant reduction in pain, improved their quality of life, and even showed signs of cartilage regrowth.

Stem cell shot reverses osteoarthritis, repairs knee cartilage, cuts pain by 58%

Birmingham, AL

As a registered dietitian and avid runner, Beth Kitchin has had a healthy routine all her life. She ate well, loved to jog, hike and lift weights, ran a couple of marathons, and practiced yoga and tai chi. Kitchin had “absolutely” no health problems — until she started feeling a nagging pain in one of her legs in the fall of 2020.

Woman shocked leg pain is blood cancer symptom, requires 'red devil' chemo

Denver, CO

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David Heitz

More dangerous substances are entering the Denver drug supply, Harm Reduction Action Center warned in a newsletter this week. “The Iron Law of Prohibition posits that as law enforcement becomes more intense, the potency of prohibited substances increases,” HRAC Executive Director Lisa Raville wrote in the newsletter. That is exactly what is happening, she said.

Dangerous substances entering Denver drug supply

Camden, NJ

Cornelius, NC

Morristown Minute

CAMDEN, N.J. – Lisa Smith, 61, of Cornelius, North Carolina, has admitted to her role in a fraudulent scheme involving over $3.5 million in Paycheck Protection Program (PPP) loans. U.S. Attorney Philip R. Sellinger announced today that Smith pleaded guilty before U.S. District Judge Karen M. Williams in Camden federal court on July 17, 2024, to a charge of bank fraud conspiracy.

Woman Pleads Guilty to $3.5M COVID Relief Scam

Florida State

Jacksonville Today

Gov. Ron DeSantis has issued a state of emergency in Northeast Florida and across much of the state as a tropical system appears almost certain to develop. The National Hurricane Center said Friday morning that a tropical wave has a 90% chance of developing into at least a tropical depression over the next seven days. Most models show it moving into the Gulf of Mexico and then coming ashore and crossing the state, possibly moving over Northeast Florida.

Tropical system is nearly certain to develop

Savannah, GA

Daily Coffee Press

Newly returned indictments in the Southern District of Georgia include felony charges for illegal firearms possession and drug distribution, while additional defendants have been sentenced to federal prison or await further proceedings after pleading guilty to federal gun charges.

Federal Charges in Southern GA: Indictments and Sentences for Firearms and Drug Offenses

Colorado State

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Republican Donald Trump has a 7-point lead over Democrat Kamala Harris among Florida voters, 49% to 42%, according to a new poll from the University of North Florida. Four percent are backing another candidate, and 6% are undecided or didn’t answer.

New Florida poll: Trump leads; support strong for abortion and recreational weed

Ohio State

The Lantern

On Tuesday, licensed Ohio dispensaries began legally selling non-medical marijuana to consumers; however, the drug’s possession, growth and/or usage are still prohibited on Ohio State’s campus. Credit: Jefferee Woo/Tampa Bay Times/TNS [Original caption: Four citizen-led petitions with proposals to update Dallas’ charter hit the 20,000 valid signature threshold to make it on the Nov. 5 election ballot, including one that would ban police officers from arresting or citing people carrying less than four ounces of marijuana.] As of Tuesday, students 21 and older can now legally purchase marijuana in Ohio.

Dispensary sales of recreational marijuana began Tuesday; possession and usage still prohibited on Ohio State’s campus

Autism spectrum disorder risk was similar with prenatal topiramate or lamotrigine vs. no antiseizure medication exposure. Prenatal valproate was tied to a dose-dependent increased autism spectrum disorder risk. Autism spectrum disorder incidence was higher for children with prenatal exposure to antiseizure medications vs. the general population, but some associations weakened...

Childhood autism may be linked to prenatal exposure to antiseizure medication

Tennessee State

John M. Dabbs

NASHVILLE, Tenn. — The Tennessee Department of Health (TDH) has issued a health alert to clinicians statewide following reports of severe acute illnesses and adverse effects of consuming Diamond Shruumz™ brand chocolate bars, cones, and gummies. The warning comes after the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) received reports of serious health issues linked to these mushroom-containing edible products.

Tennessee Health Alert: Severe Illnesses Linked to Diamond Shruumz™ Products

“This post contains affiliate links, and I will be compensated if you make a purchase after clicking on my links.”. A dog’s esophagus is a long, flexible muscular tube that connects the throat to the stomach. It’s main function is to transport food and liquids from the mouth and into the stomach for digestion.

Understanding Esophagitis In Dogs: Symptoms, Causes, Diagnosis, and Treatments

Study findings suggest the need for individualized management of patients with IgAN following COVID-19 infection based on baseline renal function status. Findings from a recent study are providing clinicians with an overview of the impact of mild to moderate COVID-19 infection on subsequent kidney function in patients with IgA nephropathy (IgAN).1.

Kidney Function in IgA Nephropathy Not Impacted by Mild, Moderate COVID-19 Infection

Missouri State

Writers represent independent, third-party users who have joined our contributor program and self-verified their accounts. Writers are expected, like all users, to adhere to our Community Standards.

writer

CJ Coombs

Red Lobster is a casual dining restaurant and shouldn't be compared to fine dining restaurants when commenting on seafood venues. Many families who can't afford fine dining costs can go to a Red Lobster, especially if they love seafood.

Red Lobster navigates in challenging waters to find success in its future with closures and a buyer

Researchers have demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy may improve progression-free survival in patients with oligometastatic pancreatic cancer, according to a recent study published by Ludmir et al in the Journal of Clinical Oncology and previously presented at the 2024 ASCO Gastrointestinal Cancers Symposium (Abstract 603). Background.

Metastasis-Directed Radiation Therapy Plus Chemotherapy in Oligometastatic Pancreatic Cancer

NewsBreak

Phase 1/2 Trial of Silmitasertib in Sarcoma and Brain Tumors to Proceed

The study will evaluate silmitasertib, a novel agent, for the treatment of pediatric and adult patients with relapsed/refractory solid tumors. The FDA has issued a “study...

Phase 1/2 Trial of Silmitasertib in Sarcoma and Brain Tumors to Proceed

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