Columbus, OH

Dr Sekeres discusses how he approaches second-line therapy selection in ESA-refractory, transfusion-dependent lower-risk MDS (LR-MDS) patients, specifically with luspatercept. Please discuss how you approach second-line therapy selection in ESA-refractory, transfusion-dependent lower-risk MDS (LR-MDS) patients. (LUSPATERCEPT)

Second-Line Therapy for ESA-Refractory, Transfusion Dependent Lower-Risk MDS: Luspatercept

North Carolina State

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Town Talks

Biscuitville, a North Carolina-based chain, has been named the No. 1 fast-food breakfast spot in the nation by USA Today's 10Best. This accolade comes after a month-long voting period where people across the country chose their favorite breakfast destinations.

North Carolina-based chain ranks No. 1 in the nation for fast-food breakfast. Here’s why

A multicenter, randomized, double-blind, placebo-controlled trial done performed in the the United Kingdom June 2014 to October 2017), enrolled 207 adult patients with symptomatic, radiographic KOA and knee pain (severity ≥4 out of 10) on most days in the past 3 months, after an inadequate response to analgesic medications.

Pain Reduction with Methotrexate in Knee Osteoarthritis

Chicago, IL

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Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Review of: Risk of nonarteritic anterior ischemic optic neuropathy in patients prescribed semaglutide. Hathaway J, Sha M, Hathaway D, et al. JAMA Ophthalmology, in press 2024. Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) prescribed to assist with weight management in patients with type 2 diabetes (T2D) or those who are overweight/obese, and there have been anecdotal reports of nonarteritic anterior ischemic optic neuropathy (NAION) in patients taking this medication. This single-center, observational study compared patients prescribed semaglutide to matched patients prescribed other medications for diabetes and found a greater risk of NAION in the semaglutide cohort, though additional studies are needed to verify this relationship and causality cannot be inferred.

Semaglutide May Be Associated With an Increased Risk of Developing NAION

Raleigh, NC

Big cities are known for their hustle and bustle, drawing people in who crave excitement, variety, and entertainment. But bigger isn’t always better, or at least not for Raleigh, North Carolina.

North Carolina City Named The Most Boring Town in the State

Polyps in the colon and rectum (together called colorectal polyps) are common in people over age 50. They are usually noncancerous, but certain characteristics can increase the likelihood of a polyp becoming cancerous. The risk of a polyp becoming cancerous increases with size. Polyps that are 10 millimeters (mm) or...

Colon Polyp Size Chart to Gauge Risk

Ohio State

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The Lantern

On Tuesday, licensed Ohio dispensaries began legally selling non-medical marijuana to consumers; however, the drug’s possession, growth and/or usage are still prohibited on Ohio State’s campus. Credit: Jefferee Woo/Tampa Bay Times/TNS [Original caption: Four citizen-led petitions with proposals to update Dallas’ charter hit the 20,000 valid signature threshold to make it on the Nov. 5 election ballot, including one that would ban police officers from arresting or citing people carrying less than four ounces of marijuana.] As of Tuesday, students 21 and older can now legally purchase marijuana in Ohio.

Dispensary sales of recreational marijuana began Tuesday; possession and usage still prohibited on Ohio State’s campus

Mississippi State

Hinds County, MS

Mississippi News Group

A Mississippi Attorney has been charged with multiple Counts of introducing contraband into a Correctional Facility as well as consipiracy according to a press release from Hinds County Sheriff Tyree Jones.

Mississippi Attorney Charged with 3 Counts of Introducing Contraband into a Correctional Facility

Ferritin cutoffs of 30 and 45 ng/mL notably increase the rate of iron deficiency diagnoses. Guideline-recommended cutoffs for serum ferritin were linked to the incidence of iron deficiency diagnoses in primary care, according to a recent retrospective cohort study in JAMA Network Open.1. Across more than 255,000 adult primary care...

Ferritin Cutoff Choice Linked to Rates of Iron Deficiency Diagnosis

Reuters

(Reuters) - Servier Pharmaceuticals said on Tuesday the U.S. Food and Drug administration has approved the French drugmaker's treatment for a type of brain tumor, making it the first drug to get a U.S. approval for the condition.

US FDA approves Servier's brain tumor treatment

Camden, NJ

Cornelius, NC

Morristown Minute

CAMDEN, N.J. – Lisa Smith, 61, of Cornelius, North Carolina, has admitted to her role in a fraudulent scheme involving over $3.5 million in Paycheck Protection Program (PPP) loans. U.S. Attorney Philip R. Sellinger announced today that Smith pleaded guilty before U.S. District Judge Karen M. Williams in Camden federal court on July 17, 2024, to a charge of bank fraud conspiracy.

Woman Pleads Guilty to $3.5M COVID Relief Scam

Alameda, CA

Alameda Post

The unthinkable has happened. Again. A gunman has taken multiple lives. The difference this time? It happened here, in Alameda. We are an island, both physically and psychologically. I spend a lot of time explaining to people that our focus is Alameda, and Alameda alone, so our coverage doesn’t usually include stories as horrific as this one.

It Happened Again. Here.

Denver, CO

David Heitz

More dangerous substances are entering the Denver drug supply, Harm Reduction Action Center warned in a newsletter this week. “The Iron Law of Prohibition posits that as law enforcement becomes more intense, the potency of prohibited substances increases,” HRAC Executive Director Lisa Raville wrote in the newsletter. That is exactly what is happening, she said.

Dangerous substances entering Denver drug supply

South Carolina State

Explore Beaufort SC

The mantis shrimp is one tough customer. Beautiful and deadly are two words you don’t typically use to describe shrimp, but the mantis shrimp is definitely in a class of its own; earning a reputation as the ‘savage boxer of the sea’ and one of the most fearsome creatures in the ocean. And, they're right at home here in South Carolina.

Savage Boxer of the Sea: The Deadly Beauty of Mantis Shrimp

NewsNinja

A lady is cautioning others about purchasing budget earrings from Amazon, Shein, and H&M, after she experienced keloid formations on her earlobes due to wearing them. On a TikTok post that has garnered more than 334,000 likes, Sailor Rozema (@sailor.rozema), a content creator, shares a warning with her community of "dangly earring girls": the inexpensive jewelry found in fast fashion can have negative impacts on your well-being.

‘I’ll never be wearing earrings for the rest of my life’: Customer warns against buying from Shein

Statin use was linked with increased glaucoma likelihood in the overall adult All of Us Research Program population with hyperlipidemia, in individuals with optimal or high LDL-C levels, and in individuals from 60 to 69 years old. A team of researchers has investigated links between statin use and glaucoma in...

Study links statin use to higher risk of glaucoma

Colorado State

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Cardiovascular complications are among the most common comorbidities affecting people with HIV (PWH), with studies showing increased risk for myocardial infarction, heart failure, and sudden cardiac death in these individuals despite treatment with antiretroviral therapy (ART).1 Compared with people without HIV, PWH have demonstrated up to twice the risk for cardiovascular disease,2 and this difference is not clearly linked to traditional risk factors or ART.1.

Reducing the Risk of CVD in Patients with HIV

Erythritol is found in everything from drinks and baked goods to gum and candy.

Artificial sweetener erythritol could elevate heart disease risk, study suggests

NewsBreak

Second-line Treatment for RS-negative Lower-Risk MDS: Choosing Between EMA and Telomerase Inhibitor Options

Dr Sekeres shares his thoughts about the choice between an EMA and...

Second-line Treatment for RS-negative Lower-Risk MDS: Choosing Between EMA and Telomerase Inhibitor Options

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