NCCN guidelines have been updated to recommend imetelstat to treat symptomatic anemia in patients with lower-risk myelodysplastic syndromes. The National Comprehensive Cancer Network (NCCN) has updated its clinical practice guidelines in oncology to now recommend imetelstat (Rytelo) as a Category 1 and 2A treatment for symptomatic anemia in patients with lower-risk myelodysplastic syndromes (MDS).1.

Updated NCCN Guidelines Recommend Imetelstat to Treat Anemia in Lower-Risk MDS

Dr Sekeres discusses key takeaways for optimizing anemia management in lower-risk MDS, as well as where he sees the most significant unmet needs. Please share your key takeaways for optimizing anemia management in lower-risk MDS, and where you see the most significant unmet needs.

Optimizing Anemia Management in Lower-Risk MDS: Key Takeaways

shefinds

Supplements are often taken to improve health and fill nutritional gaps, but not all are as beneficial as they seem. Some supplements, particularly when taken in excess or without proper guidance, can have unintended negative effects. For example, certain supplements can unknowingly contribute to high blood pressure and increase the risk of cardiovascular events.

4 Worst Supplements That Could Actually Lead To High Blood Pressure And Cardiovascular Events: Licorice Root & More

Review of: Risk of nonarteritic anterior ischemic optic neuropathy in patients prescribed semaglutide. Hathaway J, Sha M, Hathaway D, et al. JAMA Ophthalmology, in press 2024. Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) prescribed to assist with weight management in patients with type 2 diabetes (T2D) or those who are overweight/obese, and there have been anecdotal reports of nonarteritic anterior ischemic optic neuropathy (NAION) in patients taking this medication. This single-center, observational study compared patients prescribed semaglutide to matched patients prescribed other medications for diabetes and found a greater risk of NAION in the semaglutide cohort, though additional studies are needed to verify this relationship and causality cannot be inferred.

Semaglutide May Be Associated With an Increased Risk of Developing NAION

Community Voices represent independent, third-party users who have joined our contributor program but not yet verified their accounts. Community Voices are expected, like all users, to adhere to our Community Standards.

community_voice

NewsNinja

A lady is cautioning others about purchasing budget earrings from Amazon, Shein, and H&M, after she experienced keloid formations on her earlobes due to wearing them. On a TikTok post that has garnered more than 334,000 likes, Sailor Rozema (@sailor.rozema), a content creator, shares a warning with her community of "dangly earring girls": the inexpensive jewelry found in fast fashion can have negative impacts on your well-being.

‘I’ll never be wearing earrings for the rest of my life’: Customer warns against buying from Shein

Among patients with fibromyalgia, there was a moderate negative correlation between vitamin D and physical functioning as well as between magnesium and stiffness. An exploratory study evaluating the link between specific micronutrients and the symptoms of fibromyalgia revealed vitamin D and magnesium played a role in physical function and stiffness among patients.1.

Vitamin D, Magnesium Deficiency Linked to Worse Fibromyalgia Symptoms

Florida State

Contributors represent independent, third-party users who have joined our contributor program and self-verified their accounts. They have also demonstrated their experience writing hard news for other outlets. Contributors are expected, like all users, to adhere to our Community Standards.

contributor

Jacksonville Today

Gov. Ron DeSantis has issued a state of emergency in Northeast Florida and across much of the state as a tropical system appears almost certain to develop. The National Hurricane Center said Friday morning that a tropical wave has a 90% chance of developing into at least a tropical depression over the next seven days. Most models show it moving into the Gulf of Mexico and then coming ashore and crossing the state, possibly moving over Northeast Florida.

Tropical system is nearly certain to develop

Republican Donald Trump has a 7-point lead over Democrat Kamala Harris among Florida voters, 49% to 42%, according to a new poll from the University of North Florida. Four percent are backing another candidate, and 6% are undecided or didn’t answer.

New Florida poll: Trump leads; support strong for abortion and recreational weed

Camden, NJ

Cornelius, NC

Morristown Minute

CAMDEN, N.J. – Lisa Smith, 61, of Cornelius, North Carolina, has admitted to her role in a fraudulent scheme involving over $3.5 million in Paycheck Protection Program (PPP) loans. U.S. Attorney Philip R. Sellinger announced today that Smith pleaded guilty before U.S. District Judge Karen M. Williams in Camden federal court on July 17, 2024, to a charge of bank fraud conspiracy.

Woman Pleads Guilty to $3.5M COVID Relief Scam

Denver, CO

David Heitz

More dangerous substances are entering the Denver drug supply, Harm Reduction Action Center warned in a newsletter this week. “The Iron Law of Prohibition posits that as law enforcement becomes more intense, the potency of prohibited substances increases,” HRAC Executive Director Lisa Raville wrote in the newsletter. That is exactly what is happening, she said.

Dangerous substances entering Denver drug supply

Study shows patients 80 years and older with atrial fibrillation treated with a lower dose of edoxaban experienced fewer major gastrointestinal bleeding events for each additional ischemic stroke. Patients aged 80 years and above with atrial fibrillation (AF) may gain a benefit from treatment with lower-dose anticoagulants regardless of existing...

Phase III Trial Shows Older Patients with Atrial Fibrillation May Benefit From Lower-Dose Anticoagulants

In the United States, approximately 47% of adults have hypertension, a condition characterized by consistently elevated blood pressure. This statistic is concerning as high blood pressure is a significant risk factor for serious health issues, including heart disease, stroke, and kidney disease. Elevated blood pressure often goes unnoticed due to its asymptomatic nature, earning it the nickname “the silent killer.” Health practitioners must prioritize blood pressure monitoring and management, as early detection and treatment can prevent complications and improve overall health outcomes. By addressing hypertension, practitioners can significantly reduce the burden of cardiovascular diseases and enhance the quality of life for their patients.

9 Effective Ways to Lower Blood Pressure Naturally

Missouri State

Writers represent independent, third-party users who have joined our contributor program and self-verified their accounts. Writers are expected, like all users, to adhere to our Community Standards.

writer

CJ Coombs

Red Lobster is a casual dining restaurant and shouldn't be compared to fine dining restaurants when commenting on seafood venues. Many families who can't afford fine dining costs can go to a Red Lobster, especially if they love seafood.

Red Lobster navigates in challenging waters to find success in its future with closures and a buyer

No, pallet shelters for people experiencing homelessness don’t fold into caskets. It’s a question a reader posed one of the first times I wrote about pallet shelters. I find the pallet shelters to be more palatable than ice fishing tents. The Colorado Village Collaborative operates both micro-communities and the so-called Safe Outdoor Spaces with the tents. We all learned the tents are not safe when a fire roared through a CVC Safe Outdoor Space, destroying the compound quickly. Officials never disclosed a cause of the fire.

Opinion: No, pallet shelters for homeless in Denver, Aurora don’t fold into caskets

South Carolina State

Explore Beaufort SC

The mantis shrimp is one tough customer. Beautiful and deadly are two words you don’t typically use to describe shrimp, but the mantis shrimp is definitely in a class of its own; earning a reputation as the ‘savage boxer of the sea’ and one of the most fearsome creatures in the ocean. And, they're right at home here in South Carolina.

Savage Boxer of the Sea: The Deadly Beauty of Mantis Shrimp

Tennessee State

John M. Dabbs

NASHVILLE, Tenn. — The Tennessee Department of Health (TDH) has issued a health alert to clinicians statewide following reports of severe acute illnesses and adverse effects of consuming Diamond Shruumz™ brand chocolate bars, cones, and gummies. The warning comes after the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) received reports of serious health issues linked to these mushroom-containing edible products.

Tennessee Health Alert: Severe Illnesses Linked to Diamond Shruumz™ Products

Colorado State

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Ohio State

The Lantern

On Tuesday, licensed Ohio dispensaries began legally selling non-medical marijuana to consumers; however, the drug’s possession, growth and/or usage are still prohibited on Ohio State’s campus. Credit: Jefferee Woo/Tampa Bay Times/TNS [Original caption: Four citizen-led petitions with proposals to update Dallas’ charter hit the 20,000 valid signature threshold to make it on the Nov. 5 election ballot, including one that would ban police officers from arresting or citing people carrying less than four ounces of marijuana.] As of Tuesday, students 21 and older can now legally purchase marijuana in Ohio.

Dispensary sales of recreational marijuana began Tuesday; possession and usage still prohibited on Ohio State’s campus

Newark, NJ

Paterson, NJ

NEWARK, N.J. – Jasmine McGregor, 32, and Jhenelle Lewis, 35, both of Paterson, New Jersey, have pleaded guilty to conspiring with a physician to distribute oxycodone, a powerful opioid, without legitimate medical justification. The announcement was made today by U.S. Attorney Philip R. Sellinger.

Paterson Residents Conspired with Physician to Illegally Distribute Opioids

It’s important to communicate with the patient’s comanaging doctors to adjust necessary medications. There are four direct oral anticoagulants approved for atrial fibrillation and venous thromboembolism: apixaban (Eliquis), dabigatran (Pradaxa), edoxaban (Savaysa) and rivaroxaban (Xarelto). Click image to enlarge. The body is an interconnected system and, as clinicians...

Some Blood Thinners May Increase Conversion to Wet AMD

NewsBreak

DeZern Discusses Incorporating Current Options for Managing Anemia in Low-Risk MDS

During a Case-Based Roundtable® event, Amy DeZern, MD, MHS, discussed dosing approaches for managing anemia with luspatercept in patients with low-risk myelodysplastic syndrome. Peers & Perspectives...

DeZern Discusses Incorporating Current Options for Managing Anemia in Low-Risk MDS

Comments / 0