Rahul Banerjee, MD, FACP, discusses key takeaways from his presentation at an OncLive State of the Science Summit on multiple myeloma. Rahul Banerjee, MD, FACP, assistant professor, Clinical Research Division, Fred Hutch Cancer Center; member, the International Myeloma Working Group; assistant professor, Division of Hematology and Oncology, University of Washington, discusses key takeaways from the presentation he gave at an OncLive® State of the Science Summit™ on multiple myeloma, highlighting the disease’s evolving treatment paradigm.

Dr Banerjee on the Evolving Multiple Myeloma Treatment Paradigm

Servier has expanded its IDH drug armamentarium with the FDA approval for an IDH1/2 dual inhibitor. The approval represents the first major treatment advance in low-grade brain cancer in more than two decades. The new FDA approval is for Servier’s Voranigo, or vorasidenib, for adult and children ages 12 and...

Servier snags FDA approval for Voranigo, the first targeted therapy for a common type of brain tumor

The FDA has approved denileukin diftitox-cxdl for relapsed/refractory cutaneous T-cell lymphoma after at least 1 prior systemic therapy. The FDA has approved denileukin diftitox-cxdl (Lymphir) for the treatment of patients with relapsed/refractory cutaneous T-cell lymphoma (CTCL) after at least 1 prior systemic therapy.1. The approval was supported by data from...

FDA Approves Denileukin Diftitox for R/R Cutaneous T-Cell Lymphoma

“These findings indicate that renalase-1 is a potential antigen for TCR recognition in melanoma and could be considered as a target for immunotherapy.”. BUFFALO, NY- August 8, 2024 – A new research paper was published in Oncotarget's Volume 15 on August 5, 2024, entitled, “Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival.”

TCR CDR3s and renalase-1 linked to increased melanoma survival

Surgery isn’t a typical treatment for multiple myeloma. But in some cases, surgery may be necessary to address complications from the disease. Multiple myeloma is a rare type of cancer that causes abnormal cells to develop in your bone marrow. As multiple myeloma spreads, it can lead to bone damage or loss.

The Role of Surgery in Treating Multiple Myeloma

Researchers have demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy may improve progression-free survival in patients with oligometastatic pancreatic cancer, according to a recent study published by Ludmir et al in the Journal of Clinical Oncology and previously presented at the 2024 ASCO Gastrointestinal Cancers Symposium (Abstract 603). Background.

Metastasis-Directed Radiation Therapy Plus Chemotherapy in Oligometastatic Pancreatic Cancer

Everyday Health

Learn about eosinophilic esophagitis (EoE) and its symptoms, including chronic cough, treatment options, and diagnosis methods.

Can Eosinophilic Esophagitis Be the Reason Behind Your Chronic Cough?

MedwireNews: Findings from the Cancer of the Pancreas Screening program in the USA support the use of annual endoscopic ultrasound (EUS) or magnetic resonance imaging (MRI) for patients with a familial or genetic predisposition for pancreatic ductal adenocarcinoma (PDAC). “Surveillance of high-risk individuals for PDAC using EUS and MRI within...

Annual screening supported for people at high-risk of pancreatic ductal adenocarcinoma

A second dendritic cell vaccine has received fast track designation from the Food and Drug Administration. The Food and Drug Administration (FDA) has granted a fast track designation to a dendritic cell vaccine for the treatment of patients with pancreatic ductal adenocarcinoma. Immuno-oncology company Diakonos Oncology Corporation announced the designation...

FDA Fast Tracks Pancreatic Cancer Vaccine

Non-Hodgkin Lymphoma (NHL) is a type of cancer that starts in the lymphatic system, which is part of the body's immune system. Unlike Hodgkin lymphoma, NHL can arise in various lymphoid tissues throughout the body. Did you know that there are more than 60 different types of NHL? This diversity makes it a complex disease to diagnose and treat. Symptoms can vary widely, from swollen lymph nodes to unexplained weight loss. Risk factors include age, weakened immune system, and certain infections. Treatment options range from chemotherapy to targeted therapies. Understanding NHL can help in early detection and better management.

14 Facts About Non Hodgkin Lymphoma

Florida State

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Jacksonville Today

Gov. Ron DeSantis has issued a state of emergency in Northeast Florida and across much of the state as a tropical system appears almost certain to develop. The National Hurricane Center said Friday morning that a tropical wave has a 90% chance of developing into at least a tropical depression over the next seven days. Most models show it moving into the Gulf of Mexico and then coming ashore and crossing the state, possibly moving over Northeast Florida.

Tropical system is nearly certain to develop

Early-stage trials in Alzheimer’s disease patients and studies in mouse models of the disease have suggested positive impacts on pathology and symptoms from exposure to light and sound presented at the “gamma” band frequency of 40 Hz. A new study zeroes in on how 40Hz sensory stimulation helps to sustain an essential process in which the signal-sending branches of neurons, called axons, are wrapped in a fatty insulation called myelin. Often called the brain’s “white matter,” myelin protects axons and insures better electrical signal transmission in brain circuits.

Study reveals ways in which 40Hz sensory stimulation may preserve brain’s ‘white matter’

Thyroid cancer stages range from 1 to 4 (sometimes referred to in Roman numerals as I, II, III, and IV). Stage 4 thyroid cancer is the most serious; stage 1 is the least severe. The stage of someone's cancer is determined by the size and spread of cancer cells from a tumor's primary site, in this case, the thyroid gland.

What Are the Stages of Thyroid Cancer?

In the phase II CUPISCO trial reported in The Lancet, Krämer et al found that molecularly guided therapy in patients with unfavorable nonsquamous cancer of unknown primary who had disease control on first-line platinum-based therapy resulted in better progression-free survival vs patients who continued chemotherapy. Study Details. In the...

Cancer of Unknown Primary: Molecularly Guided Therapy After Disease Control on Platinum-Based Chemotherapy

Michigan State

Each year, hundreds of thousands of Michigan parents worry whether they can afford to feed their children. Increased food prices, the state’s housing crisis, and the end of COVID-era financial support have all led to more Michigan families experiencing food insecurity today than before the pandemic. Now, a new report led by the University of Michigan School of Public Health details the first-hand experiences of these families; their challenges signing up for food assistance, the stress and shame of having to ask for help with food, and parents’ deep commitment to making sure their children are fed—even if it means that they go without.

Report examines Michigan families’ experience with food access and assistance, outlines changes for improved support

Approval marks the first time an immuno-oncology regimen has demonstrated a survival benefit for all adults with primary advanced or recurrent endometrial cancer, company says. The FDA has approved an expanded indication for GSK’s Jemperli (dostarlimab) to include treatment of all adults with primary advanced or recurrent endometrial cancer. According...

FDA Expands Approval of GSK’s Jemperli in Combination with Chemotherapy for Adults with Primary Advanced or Recurrent Endometrial Cancer

Assessing internal mammary lymph node involvement is beneficial in determining the pre-test probability of tuberculous pleurisy. Assessment of internal mammary lymph nodes (IMLNs) involvement is key in determining the pre-test probability of tuberculous pleurisy (TP), according to results published in Pulmonology Journal. Researchers noted that diagnosing TP can be difficult...

Improving Tuberculosis Pleurisy Diagnosis

According to allegations raised in a recently filed product liability lawsuit against the Ozempic manufacturer Novo Nordisk, users and the medical community have not been adequately warned about the severity of gastrointestinal events that may be caused by the medication, which is now used by millions of Americans. The complaint...

Three Years of Ozempic Use Led to Gastroparesis Diagnosis, Lawsuit Alleges

Offering patients with concussion a type of brain scan known as diffusion tensor imaging MRI could help identify the one in three people who will experience persistent symptoms that can be life changing, say Cambridge researchers. Around one in 200 people in Europe every year will suffer concussion. In the...

One-Third of Concussion Patients Diagnosed With "Hidden Disease" Using Advanced MRI

Charlottesville, VA

Nearly a quarter of children with recurrent wheezing have “silent” lung infections that would be better treated with antiviral medications than commonly prescribed steroids that can carry lifelong side effects, new research from the University of Virginia School of Medicine reveals. Pediatric pulmonologist W. Gerald Teague, MD, was...

Recurrent wheezing in children linked to 'silent' viral infections

NewsBreak

Possibilities for the early diagnosis of head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is a diverse group of cancers originating from the mucosal linings of the oral cavity, oropharynx, hypopharynx, and larynx....

Possibilities for the early diagnosis of head and neck squamous cell carcinoma

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