Interesting Engineering

Patients experienced a significant reduction in pain, improved their quality of life, and even showed signs of cartilage regrowth.

Stem cell shot reverses osteoarthritis, repairs knee cartilage, cuts pain by 58%

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Supplements are often taken to improve health and fill nutritional gaps, but not all are as beneficial as they seem. Some supplements, particularly when taken in excess or without proper guidance, can have unintended negative effects. For example, certain supplements can unknowingly contribute to high blood pressure and increase the risk of cardiovascular events.

4 Worst Supplements That Could Actually Lead To High Blood Pressure And Cardiovascular Events: Licorice Root & More

A multicenter, randomized, double-blind, placebo-controlled trial done performed in the the United Kingdom June 2014 to October 2017), enrolled 207 adult patients with symptomatic, radiographic KOA and knee pain (severity ≥4 out of 10) on most days in the past 3 months, after an inadequate response to analgesic medications.

Pain Reduction with Methotrexate in Knee Osteoarthritis

A range of conditions, including alcohol or medication overuse, nonalcoholic fatty liver disease (NAFLD), and chronic infections, can damage your liver. However, the early signs of liver damage are subtle, and the initial stages of liver disease are "silent," or asymptomatic. By the time you recognize symptoms, your liver is already significantly damaged.

Signs of Liver Damage and Ways to Tell

Acute kidney injury (AKI) is one of the most frequent complications of cardiac surgery and the cause is complex. Renal hypoperfusion from decreased glomerular filtration rate after cardiopulmonary bypass is a major contributor. 1 This in combination with exogenous toxins, endogenous metabolites, oxidative stress, bleeding and reperfusion injury can all...

The PROTECTION Trial – A Randomized Trial of Intravenous Amino Acids for Kidney Protection

Findings suggest increased intensity of IgM deposits in patients with positive IgM deposition may contribute to adverse clinicopathologic presentation and clinical outcomes. Findings from a recent study are providing clinicians with an overview of the value of glomerular IgM deposit intensity in patients with IgA nephropathy (IgAN).1. Although results showed...

Glomerular IgM Deposit Intensity Shows Clinical Significance in IgA Nephropathy

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NewsNinja

"They accidentally gave us 2 washers and a dryer when we only ordered 1 of each". Last month, Lowe’s experienced a glitch that lowered the price of its $2,300 Midea jumbo capacity refrigerator to just $169.

‘Lowe’s messed up’: Shopper says they got $2,300 fridge at Lowe’s for just $169

Among patients with fibromyalgia, there was a moderate negative correlation between vitamin D and physical functioning as well as between magnesium and stiffness. An exploratory study evaluating the link between specific micronutrients and the symptoms of fibromyalgia revealed vitamin D and magnesium played a role in physical function and stiffness among patients.1.

Vitamin D, Magnesium Deficiency Linked to Worse Fibromyalgia Symptoms

Everyday Health

Learn about eosinophilic esophagitis (EoE) and its symptoms, including chronic cough, treatment options, and diagnosis methods.

Can Eosinophilic Esophagitis Be the Reason Behind Your Chronic Cough?

Beta-blockers lower your heart rate and reduce your heart’s workload. If you have heart failure, they may help improve your cardiac function. Possible side effects include unusually slow heart rate and low blood pressure. Beta-blocker medications block the production of two stress hormones called epinephrine and norepinephrine. Doctors may...

Do Beta-Blockers Work for Heart Failure?

The U.S. Food and Drug Administration (FDA) has approved the world’s first nasal spray drug, neffy (epinephrine nasal spray), for the treatment of Type I anaphylaxis. Approved on August 9, 2024, this adrenaline nasal spray offers a new option for treating severe allergic reactions in adults and pediatric patients weighing at least 30 kg. Further, this approval introduces a significant alternative for patients who delay treatment due to an aversion to injections.

The First-Ever Nasal Spray for Anaphylactic Shock Gets FDA Approval

Heterogenous presentation of atopic dermatitis can present a challenge to correct diagnosis. How often do patients present to your clinic who have been misdiagnosed?

Heterogenous Presentation of Atopic Dermatitis

New study suggests MRI-derived pressure measurements indicate a 5-fold increase in heart failure risk. Findings from a study of nearly 40,000 adults suggest use of magnetic resonance imaging (MRI) could revolutionize the prediction and stratification of risk for heart failure among the general population. An analysis of data from the...

Wedge Pressure, Measured Using Cardiac MRI, Can Aid in Predicting Incident Heart Failure

North Carolina State

Town Talks

In North Carolina, the divorce process can be challenging, particularly due to the mandatory one-year separation requirement. This law mandates that couples must live separately for at least a year before filing for divorce, a rule that can be frustrating for many.

You might be granted a divorce in North Carolina if your spouse is ‘incurably insane.’ Here’s how

In this interview, Kim speaks about the significance of the FDA approval of neffy for patients who face the threat of anaphylaxis and other severe allergic reactions. The US Food and Drug Administration (FDA) approved an epinephrine nasal spray formulated for emergency treatment of adults and children with severe allergic reactions like anaphylaxis. This treatment, the first non-injectable option for severe allergic reactions, is known as ‘neffy.’1.

Impact of Nasal Epinephrine Spray for Patients with Severe Allergies, with Edwin H. Kim, MD

Tampa, FL

Approval of neffy marks a significant advancement in epinephrine delivery, offering a less painful alternative to traditional needle injections. The FDA has approved ARS Pharmaceuticals’ neffy (epinephrine nasal spray), a first-in-class needle-free, nasal spray treatment for type I allergic reactions, such as anaphylaxis, for adults and children weighing 66 lbs. or more. According to the company, this approval offers a less painful alternative to traditional needle injections, which are often delayed due to anxiety, potentially worsening allergic reactions.1.

FDA Approves First Epinephrine Nasal Spray for Type I Allergic Reactions Including Anaphylaxis

Medications for Crohn's disease—a chronic, progressive, and relapsing inflammatory bowel disease (IBD)—include a variety of conventional and newer prescription therapies. These include drugs such as aminosalicylates, steroids, and antibiotics. Other novel treatments approved in recent years include biologics and immunosuppressants. All of these treatment options aim to decrease immune system activity to reduce inflammation.

Medications for Crohn’s Disease

The spleen tyrosine kinase pathway was upregulated in patients that had severe toxicities from immune checkpoint inhibitor therapy. This signature accurately identified 60% of patients with toxicities. Researchers identified a gene signature that can predict which group of patients with melanoma will experience severe immune-related adverse events when treated with...

Gene signature predicts severe adverse events from ICI therapy for melanoma

FOR APPOINTMENTS CALL: (956) 362-ENDO (3636) Fatty liver, also known as Steatotic Liver Disease, refers to the deposit of fat particles within the liver that in some patients may cause chronic inflammation and if not corrected even lead to liver cirrhosis. It is present in roughly one out of every three individuals and now represents the most common indication for liver transplantation in women and patients over the age of 65, however, often remains undiagnosed. Risk factors for the development of fatty liver are metabolic diseases such as pre-diabetes, type 2 diabetes mellitus, high cholesterol, obesity, and hypertension.

FATTY LIVER AND CIRRHOSIS: WHAT YOU NEED TO KNOW

Secondary hypertension is when a person has high blood pressure due to another condition, such as kidney disease. Treating the underlying condition may reverse it. Genetic factors, diet, sedentary lifestyle, poor sleep, smoking, alcohol misuse, and obesity can cause primary hypertension. Secondary hypertension stems directly from another condition, such as...

What to know about secondary hypertension

NewsBreak

Abrocitinib Drug Survival Significantly Higher Than Dupilumab for Atopic Dermatitis

This analysis compared drug survival rates of abrocitinib and dupilumab in the treatment of adults with eczema, with different benefits highlighted for both therapies. Abrocitinib has...

Abrocitinib Drug Survival Significantly Higher Than Dupilumab for Atopic Dermatitis

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