Journal of Translational Medicine volume 22, Article number: 754 (2024) Cite this article. Organoids are approved by the US FDA as an alternative to animal experiments to guide drug development and for sensitivity screening. Stable organoids models of gastric cancer are desirable for personalized medicine and drug screening. Methods. Tumor...

Paired organoids from primary gastric cancer and lymphatic metastasis are useful for personalized medicine

Two new studies have outlined major new findings in Parkinson's disease genetics. New research reported in the journal Brain has shown that genetic factors could be a far more significant influence on Parkinson's disease than thought. This study included 15,000 participants and was open to individuals who had received any type of Parkinson's diagnosis.

New Findings in Parkinson's Genetics may aid Diagnostics & Treatment

Port Richey, FL

Writers represent independent, third-party users who have joined our contributor program and self-verified their accounts. Writers are expected, like all users, to adhere to our Community Standards.

writer

Akeena

Florida’s buffet lovers are in for a shocker as the popular Royal Sushi Buffet & Hibachi in Port Richey has been temporarily shut down following a state inspection. This isn’t the first time the eatery has faced such trouble, but the recent closure has sparked quite a buzz among its loyal patrons and food enthusiasts alike.

Live roaches, flying objects in the kitchen and soiled shelves- Buffet closed again in Florida

Ohio State

Contributors represent independent, third-party users who have joined our contributor program and self-verified their accounts. They have also demonstrated their experience writing hard news for other outlets. Contributors are expected, like all users, to adhere to our Community Standards.

contributor

The Lantern

On Tuesday, licensed Ohio dispensaries began legally selling non-medical marijuana to consumers; however, the drug’s possession, growth and/or usage are still prohibited on Ohio State’s campus. Credit: Jefferee Woo/Tampa Bay Times/TNS [Original caption: Four citizen-led petitions with proposals to update Dallas’ charter hit the 20,000 valid signature threshold to make it on the Nov. 5 election ballot, including one that would ban police officers from arresting or citing people carrying less than four ounces of marijuana.] As of Tuesday, students 21 and older can now legally purchase marijuana in Ohio.

Dispensary sales of recreational marijuana began Tuesday; possession and usage still prohibited on Ohio State’s campus

Lake Mary, FL

If you're a fan of hearty breakfasts and brunches in Florida, you might have had Keke’s Cafe on your radar. Known for its generous portions and friendly service, Keke’s has been a go-to spot for many. However, the Lake Mary location recently hit a bump in the road, resulting in a temporary shutdown following a state inspection that uncovered 15 violations.

Breakfast Eatery Closed in Florida for Roaches, Dirty Hands, and Cold Foods Over 41 Degrees

South Dakota State

Community Voices represent independent, third-party users who have joined our contributor program but not yet verified their accounts. Community Voices are expected, like all users, to adhere to our Community Standards.

community_voice

Herbie J Pilato

Former child star Bobby Buntrock's life ended in tragedy. Best known as Harold “Sport” Baxter on the popular 1960s TV sitcom Hazel, Butrock died at only 21 years old in a car accident in 1974.

The Tragic Death of Child Star Bobby Buntrock, and How TV's 'Hazel' Shirley Booth Protected him

A team of researchers from Portugal and Belgium presented a paper highlighting the case of a patient with conjunctival CAM and offered an overview of the differential diagnosis and management of pigmented lesions of the conjunctiva. A team of researchers has conducted an investigation highlighting the case of a patient...

Researchers offer a case report, overview of the differential diagnosis of pigmented lesions of the conjunctiva

Chicago, IL

Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Raleigh, NC

Town Talks

Big cities are known for their hustle and bustle, drawing people in who crave excitement, variety, and entertainment. But bigger isn’t always better, or at least not for Raleigh, North Carolina.

North Carolina City Named The Most Boring Town in the State

Devra Lee

Disclaimer: This content was written by Devra Lee for general informational and entertainment purposes only. This service is to provide astrological information that has been researched, recorded, and observed by the author.

Horoscope for Tuesday, August 13th

Epstein-Barr Virus-specific T cells in multiple sclerosis (MS) showed significant autoreactivity to central nervous system antigens, indicating a potential mechanism for MS-related damage. A new study published in PLOS Pathogens showed that elevated serum Epstein-Barr Virus (EBV)-specific antibody responses in a group of patients with multiple sclerosis (MS) extended beyond...

Broader Immune Dysregulation Associated With Epstein-Barr Virus in Multiple Sclerosis

shefinds

When it comes to maintaining optimal health, supplements can often be a great addition to your diet. However, it’s important to exercise caution; some supplements may pose significant risks. While supplements are often marketed as natural and beneficial, excessive or improper use can lead to serious health consequences. This is oftentimes especially true when it comes to the health of your liver and kidneys.

6 Unexpected Supplements That May Actually Be Leading To Kidney & Liver Damage, According To Experts: Green Tea Extract & More

South Carolina State

Colleton County, SC

Explore Beaufort SC

Some beachgoers were in for a surprise this week when a bizarre looking prehistoric fish washed ashore in Colleton County along Edisto Beach at Edisto Beach State Park. It turned out to be an atlantic sturgeon.

Rare Atlantic sturgeon washes ashore on South Carolina beach

Colorado State

David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

A discovery regarding Mrc1 (Mediator of Replication Checkpoint 1)—a fission yeast protein involved in DNA replication—has been published in Cell. The discovery is the result of an international research collaboration, led by Professors Genevieve Thon and Anja Groth at the University of Copenhagen. Dr. Sebastian Charlton, shared first...

International team discovers key protein that helps cells maintain their identity

MONDAY, Aug. 12, 2024 (HealthDay News) — For patients with cervical radiculopathy, posterior surgery is noninferior to anterior surgery with respect to success rate and reduction in arm pain, according to a study published online July 24 in the Journal of Bone & Joint Surgery. Nadia F. Simões de...

Posterior Surgery Noninferior to Anterior for Cervical Radiculopathy

Doctors can diagnose fatty liver disease, now called metabolic dysfunction-associated steatotic liver disease (MASLD), using blood tests that measure serum liver enzyme levels. Elevated enzyme levels may indicate inflammation and disease in the liver. Instead of nonalcoholic fatty liver disease (NAFLD), experts now call it metabolic dysfunction-associated steatotic liver disease...

What Blood Tests Can Diagnose Fatty Liver Disease?

The following is a summary of “Derivation and validation of a machine learning model for the prevention of unplanned dialysis,” published in the May 2024 issue of Nephrology by Klamrowski et al. Half of all patients with advanced chronic kidney disease (CKD) progressing towards kidney failure start dialysis...

ML Models Accurately Predict Kidney Failure Risk and Unplanned Dialysis in Advanced CKD

Acute kidney injury (AKI) is one of the most frequent complications of cardiac surgery and the cause is complex. Renal hypoperfusion from decreased glomerular filtration rate after cardiopulmonary bypass is a major contributor. 1 This in combination with exogenous toxins, endogenous metabolites, oxidative stress, bleeding and reperfusion injury can all...

The PROTECTION Trial – A Randomized Trial of Intravenous Amino Acids for Kidney Protection

Massachusetts State

Dianna Carney

Sandy Paws Rescue Inc., a foster-based rescue organization in Massachusetts, recently shared their furry friends who have been waiting the longest to find their forever homes. From a puppy who is housebroken and loves toys to a little five-year-old dog who is a great snuggle buddy and loves other dogs, each dog is unique but has one thing in common- they need a family who will love them. Get to know these five great dogs below, and don't forget to leave a comment to let me know which pup stole your heart!

Local Animal Rescue Shares Dogs Who've Been Looking For Love The Longest

NewsBreak

Metabolic reprogramming of poly(morpho)nuclear giant cells determines glioblastoma recovery from doxorubicin-induced stress

Journal of Translational Medicine volume 22, Article number: 757 (2024) Cite this article. Multi-drug resistance of poly(morpho)nuclear giant cells (PGCs) determines their cytoprotective and generative potential...

Metabolic reprogramming of poly(morpho)nuclear giant cells determines glioblastoma recovery from doxorubicin-induced stress

Comments / 0