MILAN, Italy — In the ongoing battle against cancer, researchers are constantly seeking new weapons to add to our arsenal. Now, an intriguing approach is gaining traction: the fasting-mimicking diet (FMD). This dietary intervention, which mimics the effects of fasting while still allowing some food intake, is showing promise as a potential complement to traditional cancer treatments.

Fasting-mimicking diet: A promising ally in cancer treatment

Selpercatinib led to high response and progression-free survival rates among patients who were treatment naive and pretreated with RET-altered thyroid cancers. Treatment with selpercatinib (Retevmo) continued to deliver durable, robust response among both treatment-naive and previously treated patients with RET-mutant medullary thyroid cancer (MTC) and RET fusion-positive thyroid cancer, according to long-term safety and efficacy data from the phase 1/2 LIBRETTO-001 study (NCT03157128).1.

In LIBRETTO-001, Selpercatinib Continues to Perform in RET-Altered Thyroid Cancers

In the past two decades, immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, showing promising results against various solid tumors. This study reviews recent developments in ICIs, focusing on new targets like T cell immunoreceptor with Ig and ITIM domains (TIGIT), T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), and lymphocyte activation gene-3 (LAG-3). These targets aim to overcome resistance mechanisms limiting the effectiveness of current therapies, such as anti-PD-1 and anti-CTLA-4. By identifying and developing these new ICIs, researchers hope to improve treatment outcomes and provide new therapeutic options for cancer patients.

Tackling cancer from the inside out: A deep dive into immune checkpoint inhibitors

Researchers have discovered a new pathway used by cancer cells to infiltrate the brain and developed a promising therapy that targets this pathway with CAR T cells. Their study showed significant preclinical success in increasing survival and eradicating tumors in animal models of glioblastoma and other brain cancers. A team...

Brain Cancer Breakthrough: New Therapy Destroys Glioblastoma in Recently Unveiled Pathway

Tallahassee, FL

Florida State University researchers are giving oncologists another tool in their fight against pediatric brain cancer. In work published in Bioactive Materials, a research team led by Department of Chemistry and Biochemistry Professor Qing-Xiang “Amy” Sang showed the possibility of enhancing natural killer immune cells to improve their ability to attack a rare pediatric brain cancer.

FSU researchers show potential of new treatment for pediatric brain cancer

A JAMA Network Open study finds that noninvasive at-home colorectal cancer screening can reduce death risk by 33%. Researchers from Ohio State University and Kaiser Permanente analyzed data from 11,000 patients, showing FIT’s annual effectiveness equals a ten-year colonoscopy. The study stresses improving accessibility and addressing racial disparities in cancer screening.

At-Home Colon Cancer Test Proves Just As Effective as a Colonoscopy

Cancer Health

People with type 2 diabetes who used glucagon-like peptide analogs such as Ozempic or Mounjaro had a lower risk for multiple types of cancer compared with those who used insulin, according to study results published in JAMA Network Open. Overweight and obesity have been linked to at least 13 types...

Weight-Loss Drugs May Prevent 10 Types of Cancer

Stage 3 colorectal cancer means the cancer has spread to the nearby lymph nodes, but it has not spread to distant parts of the body. Colorectal cancer is a type of cancer that starts in the colon or rectum. Depending on where it begins, people may refer to it as colon cancer or rectal cancer.

What to know about stage 3 colorectal cancer

For people who are at high risk of developing pancreatic cancer, regular imaging tests to monitor the pancreas may help detect the disease at an earlier stage than when pancreatic cancer is typically diagnosed in the general population, according to a new study. The study also suggests that detecting pancreatic...

Surveillance for People at High Risk of Pancreatic Cancer

Thyroid lymphoma is an extremely rare but highly treatable cancer that affects the thyroid gland. It can cause a mass in the neck, difficulty swallowing, and shortness of breath. Most cases of thyroid cancer start when thyroid gland cells become cancerous. Thyroid lymphoma, meanwhile, is a disease that happens when...

What to Know About Thyroid Lymphoma

Routine blood tests could be used to more accurately diagnose cancer, even earlier, for people with stomach pain or bloating, according to a new study. Most people who report such symptoms to their doctors are referred for blood tests, say scientists, but it was not known how well those tests, used to explore a range of possible causes of illness, can predict cancer risk.

Routine Blood Tests Could Speed Up Early Cancer Diagnosis For People With Stomach Pain

Pronto disponible en español Send us your comments (link sends e-mail) A cancer diagnosis can be scary. Some cancers can be cured if caught early. Treatments like surgery, radiation, and chemotherapy can destroy many early-stage cancers. But cancer can be difficult to treat when caught later on, after it spreads.

When Cancer Spreads

Melanoma is a type of skin cancer that can spread rapidly to other areas. However, there are also slow-growing types that may develop over many years. Melanoma is not as common as other types of skin cancer. However, unlike other skin cancers, melanoma has a high risk of spreading to other areas, which makes it the most dangerous type.

How fast does melanoma spread?

The Oklahoma City Sentinel

(StatePoint) A bladder cancer diagnosis can be scary, but according to those who’ve been through it, advocating for yourself and taking charge of your journey can help you make informed decisions when it comes to your treatment to get the best care possible.
                “For me, a second opinion turned an originally doom-and-gloom picture into a more hopeful, optimistic and clear path forward,” said Mary Beth M., a bladder cancer survivor. “It’s so important to seek a second or even a third opinion if you feel...

What to Know After a Bladder Cancer Diagnosis

Corey Rhodes, 32, is keeping himself as active as possible while living with an advanced rare liver cancer. Now that his tumors have ‘stabilized,’ he is helping comfort others affected by the disease while rallying his community to assist with cancer research efforts. The type of liver cancer...

Heartburn and Shoulder Pain Led to 32-Year-Old’s Rare Liver Cancer Diagnosis: Tumor the Size of a ‘Deflated Basketball’

Medical News Today

Recent research from Italy suggests that high adherence to a Mediterranean-style diet is linked to a lower risk of death from all causes, and especially death from cardiovascular disease, in long-term cancer survivors.

Mediterranean diet may help boost longevity in cancer survivors

In part 1 of our interview with Anna Sureda, MD, PhD, president of the European Group for Blood and Marrow Transplantation, she summarized the current treatment landscape for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) and follicular lymphoma (FL). For our recent coverage of the European Hematology Association 2024 Congress,...

Advancements in R/R Lymphoma: Bispecific Antibodies in Focus

Researchers have demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy may improve progression-free survival in patients with oligometastatic pancreatic cancer, according to a recent study published by Ludmir et al in the Journal of Clinical Oncology and previously presented at the 2024 ASCO Gastrointestinal Cancers Symposium (Abstract 603). Background.

Metastasis-Directed Radiation Therapy Plus Chemotherapy in Oligometastatic Pancreatic Cancer

In the last 6 months prior to PDAC diagnosis, visceral and subcutaneous adipose tissue decreased by 12.9% and 14.7%, respectively. LDL, total cholesterol and triglycerides also decreased before diagnosis. In the 36 months prior to diagnosis of pancreatic ductal adenocarcinoma, researchers observed “predominant changes” in patients’ body composition and biochemical...

Body fat, metabolic changes before pancreatic cancer diagnosis may aid in early detection

rolling out

Cancer is a daunting diagnosis that affects millions of people worldwide. For those with a family history of cancer, the stakes are even higher. Regular screenings and tests can be life-saving by detecting cancer early when it is most treatable. Here are three crucial tests that men and women with a family history of cancer should consider:

3 crucial tests for men and women with family history of cancer

NewsBreak

New directions in targeting the multifaceted BRAF in cancer

“Here we discuss the diverse forms of BRAF alterations found in human cancers and the strategies to inhibit them in patients harboring cancers of distinct origins.”....

New directions in targeting the multifaceted BRAF in cancer

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