A company seeking to treat post-traumatic stress disorder with a combination of MDMA and talk therapy just suffered a major setback from the U.S. Food and Drug Administration. Lykos Therapeutics, the firm aiming for FDA approval, said on Friday that it received a rejection letter from the agency, which called for more research into the potential treatment’s safety and efficacy. Lykos said in response that it wants the FDA to reconsider the decision, adding that it will request a meeting to “further discuss the agency’s recommendations for a resubmission.” MDMA, also known as molly and ecstasy, is a lab-made drug developed more than a century ago by a chemist at the German pharmaceutical giant Merck.

FDA Holds Back MDMA Psychedelic Therapy Over Safety, Efficacy Concerns

CBS San Francisco

The Food and Drug Administration declined Friday to approve an application to treat post-traumatic stress disorder using the drug midomafetamine, also known as MDMA or the street drug ecstasy, citing "significant limitations" with the data submitted to the agency.Drugmaker Lykos Therapeutics had asked the FDA to approve its MDMA capsules as part of a therapy regimen they argued could be a breakthrough for treating challenging cases of PTSD. Lykos said the FDA asked for another phase 3 trial to study the safety and efficacy of MDMA. "The FDA request for another study is deeply disappointing, not just for all those who dedicated...

FDA rejects MDMA for treating PTSD, calls for redo of study, drugmaker says

Apple Valley News Now

WASHINGTON — Federal health regulators on Friday declined to approve the psychedelic drug MDMA as a therapy for PTSD, a major setback for groups seeking a breakthrough decision in favor of using mind-altering substances to treat serious mental health conditions.

FDA rejects psychedelic MDMA as treatment for PTSD, calling for additional study

Axios

The Food and Drug Administration on Friday rejected a controversial treatment for post-traumatic stress disorder that combines ecstasy with psychotherapy. Why it matters: The decision is a major blow to psychedelic therapy advocates and investors, who pressed for the MDMA-assisted therapy to become the first psychedelic treatment approved for clinical use in the United States.

FDA rejects ecstasy treatment for PTSD

Medical News Today

Recent research suggests that people who are more active in the evenings may have better brain function than those who are most active in the mornings. However, the most important takeaway is that sufficient sleep is crucial to brain health.

‘Night owls’ appear to have better brain function, new study finds

The US Sun

A SINGLE-dose nasal spray treatment could 'wash away' build ups of toxic proteins associated with Alzheimer’s disease from brain cells and improve memory, scientists say. The study - performed on mice - paves the way for new treatments against Alzheimer's and dementia, researchers at the University of Texas Medical Branch said.

Single-dose nasal spray ‘washes the brain’ of toxic Alzheimer’s proteins – paving the way for breakthrough treatment

In this study, 49.5 percent of participants had taken a benzodiazepine at some point over the past 15 years. After a follow-up interval averaging 11.2 years, 13.3 percent had developed dementia. The researchers conclude, “Overall use of benzodiazepines is not associated with increased dementia risk.”. They also find, separately,...

Long-Term Use of Benzodiazepines and Dementia Risk

Louisiana State

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Adams County, MS

Mississippi News Group

Written with artificial intelligence assistance. July 26, 2024 – According to the Darkhorse Press, a late-night raid led by the Adams County Sheriff’s Office Special Operations Group resulted in significant drug and firearm seizures, as well as multiple arrests.

Early Morning Drug Bust Leads to Multiple Arrests in Adams County

Nantucket, MA

One of the country’s largest offshore wind farms, Vineyard Wind, is generating nothing but bad PR after a turbine broke and shards of it fell into the ocean off the coast of Massachusetts last month. Debris from the massive blade washed ashore in nearby Nantucket, known for its affluent,...

Accident throws wrench in offshore wind turbines

ADHD is a very common diagnosis in children and adolescents. (Adults can have it, too). So, many families have questions. They want to know whether there are natural ways to soothe the ADHD brain without relying solely on meds. Luckily, there are natural solutions that may help with ADHD symptoms.

Natural Remedies for ADHD in Children

Community Voices represent independent, third-party users who have joined our contributor program but not yet verified their accounts. Community Voices are expected, like all users, to adhere to our Community Standards.

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NewsNinja

A lady is cautioning others about purchasing budget earrings from Amazon, Shein, and H&M, after she experienced keloid formations on her earlobes due to wearing them. On a TikTok post that has garnered more than 334,000 likes, Sailor Rozema (@sailor.rozema), a content creator, shares a warning with her community of "dangly earring girls": the inexpensive jewelry found in fast fashion can have negative impacts on your well-being.

‘I’ll never be wearing earrings for the rest of my life’: Customer warns against buying from Shein

There’s currently no cure for epilepsy. While medications can limit or eliminate seizures in many people, sometimes epilepsy doesn’t respond to medications. Understanding the mechanisms behind epilepsy can help researchers develop more effective medications and surgery. Epilepsy is a brain disorder that causes recurring seizures. During a seizure,...

Is it Possible to Cure Epilepsy?

A pharmacist explains the nuances between these two popular prescription sleep aids. Lunesta (eszopiclone) and Ambien (zolpidem) are prescription medications commonly used to treat insomnia (difficulty sleeping). This article covers the differences between these medications, their effectiveness, and important safety information. FDA Warning. Ambien and Lunesta have a black box...

Lunesta vs Ambien: Which Is Better?

A recent study on mice found that chronic social isolation reduces the activity of neurons in the anterior insular cortex region of the brain, resulting in impaired social memory. Treatment with (R)-ketamine counteracted this reduction, restoring social memory functioning in these mice. The paper was published in Molecular Psychiatry. Humans...

Study finds (R)-ketamine restores cognitive deficits induced by chronic social isolation

A recent study published in the International Journal of Geriatric Psychiatry reveals a significant link between depression and an increased risk of developing dementia. Conducted over 15 years, the study found that people with depression at the start of the study were 74% more likely to develop dementia than those without depression. Additionally, the onset of dementia occurred about two years earlier in individuals with depression. These findings underscore the importance of early detection and treatment of depression to potentially prevent future cognitive decline.

This common mental health condition increases the risk of dementia by 74%, study finds

Writers represent independent, third-party users who have joined our contributor program and self-verified their accounts. Writers are expected, like all users, to adhere to our Community Standards.

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J. Souza

A retired military officer who had been struggling with post-traumatic stress disorder (PTSD) tragically died after jumping from the world’s largest cruise ship last month, authorities confirmed.

Cruise Passenger Who Jumped from World's Largest Ship After Dispute Suffered with PTSD

Georgia State

Atlanta, GA

Daily Coffee Press

A 40-year-old man has been sentenced to over 28 years in prison for distributing significant amounts of fentanyl and other controlled substances to dealers in the Middle Georgia region. Authorities revealed that investigators uncovered evidence linking the drugs provided by the defendant, 40-year-old Lagary Williams, also known as "Frog," from Atlanta, to a fatal overdose.

Atlanta Man Sentenced to 28 Years for Supplying Deadly Fentanyl Linked to Fatal Overdose

The Marijuana Herald

The Marijuana Herald - Marijuana news and information
In 2024, a growing body of research has highlighted the potential therapeutic benefits of psilocybin, the psychedelic compound found in “magic mushrooms”. These studies, published in various peer-reviewed journals, have explored psilocybin’s effects on mental health conditions such as depression, anxiety, obsessive-compulsive disorder (OCD), and even Alzheimer’s disease, among other ailments. With that in mind, … 
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The post 10 Important Psilocybin (Magic Mushroom) Studies Published in 2024 appeared first on The Marijuana Herald.

10 Important Psilocybin (Magic Mushroom) Studies Published in 2024

Colorado State

David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Blood tests that can detect 90% of Alzheimer’s cases could revolutionize access to Alzheimer’s treatment, studies say.

Alzheimer’s blood test catches 90% of early dementia cases, study finds

NewsBreak

The MDMA therapy movement is having a rough trip

What’s worse than a rejection? Two rejections, back to back. Fresh off a thumbs-down from the FDA, the psychedelic therapies company Lykos Therapeutics says it’ll challenge...

The MDMA therapy movement is having a rough trip

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