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Supplements are often taken to improve health and fill nutritional gaps, but not all are as beneficial as they seem. Some supplements, particularly when taken in excess or without proper guidance, can have unintended negative effects. For example, certain supplements can unknowingly contribute to high blood pressure and increase the risk of cardiovascular events.

4 Worst Supplements That Could Actually Lead To High Blood Pressure And Cardiovascular Events: Licorice Root & More

Everyday Health

Learn about advanced COPD stages, symptoms, and treatments, plus pulmonary rehab, palliative care, and hospice planning.

Managing Advanced COPD: What to Expect

Thrombocytopenia is an atypically low platelet count. Acquired thrombocytopenia is caused by conditions that develop throughout your life instead of genes inherited from birth. Acquired thrombocytopenia can develop for many different reasons, such as:. thrombotic thrombocytopenic purpura, which is a medical emergency that can lead to serious internal bleeding. People...

Overview of Acquired Thrombocytopenia

Approval of Livdelzi is based on results from the Phase III RESPONSE study, which demonstrated improved key biochemical markers and reduced pruritus. The FDA has granted accelerated approval to Livdelzi (seladelpar), Gilead’s treatment for primary biliary cholangitis (PBC) in adults who either have an inadequate response to ursodeoxycholic acid (UDCA) or cannot tolerate it. According to the company, the approval was based on positive results from the Phase III RESPONSE study, where Livdelzi significantly improved key biochemical markers and reduced pruritus, a debilitating symptom of PBC. Accelerated approval was based on a reduction of ALP.1.

FDA Grants Accelerated Approval to Gilead’s Livdelzi for the Treatment of Primary Biliary Cholangitis

FOR APPOINTMENTS CALL: (956) 362-ENDO (3636) Fatty liver, also known as Steatotic Liver Disease, refers to the deposit of fat particles within the liver that in some patients may cause chronic inflammation and if not corrected even lead to liver cirrhosis. It is present in roughly one out of every three individuals and now represents the most common indication for liver transplantation in women and patients over the age of 65, however, often remains undiagnosed. Risk factors for the development of fatty liver are metabolic diseases such as pre-diabetes, type 2 diabetes mellitus, high cholesterol, obesity, and hypertension.

FATTY LIVER AND CIRRHOSIS: WHAT YOU NEED TO KNOW

The president and CEO at Alzheon shared recent insights into neurodegenerative diseases that suggest a single toxic trigger may be responsible for conditions like Alzheimer disease, leading to potential early intervention and treatment strategies. [WATCH TIME: 10 minutes]. WATCH TIME: 10 minutes. "This is the dawn of the new era...

Altering Alzheimer Care Landscape With New, Advanced Therapeutics: Martin Tolar, MD, PhD

Patients with locally advanced muscle-invasive bladder cancer may benefit from dose-dense gemcitabine and cisplatin. The treatment of preoperative dose-dense gemcitabine and cisplatin chemotherapies was well-tolerated and effective in patients with locally advanced muscle-invasive bladder cancer; however, more research is needed, an expert told CURE®. “The dose-dense part means to...

Dose-Dense Chemo for Muscle-Invasive Bladder Cancer May Be Feasible

The study was not adequately powered to assess a significant association with cancer mortalities. A new study has found a negative correlation between serum vitamin D and mortality in patients with gout and a U-shaped relationship in patients with hyperuricemia (HUA).1. “Though there are several major advances in gout treatment,...

Vitamin D Associated With Lower Risk of Mortality in Patients With Gout, Hyperuricemia

Colorado State

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David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

In the last 6 months prior to PDAC diagnosis, visceral and subcutaneous adipose tissue decreased by 12.9% and 14.7%, respectively. LDL, total cholesterol and triglycerides also decreased before diagnosis. In the 36 months prior to diagnosis of pancreatic ductal adenocarcinoma, researchers observed “predominant changes” in patients’ body composition and biochemical...

Body fat, metabolic changes before pancreatic cancer diagnosis may aid in early detection

Alkhouri explains the value of AGILE 3+ and AGILE 4, reviewing key findings from a recent study applying the scores to NHANES data to estimate MASLD fibrosis and cirrhosis. Although several noninvasive tests have emerged as potential alternatives to liver biopsy for determining the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD)-related fibrosis and cirrhosis, their overall accuracy and positive predictive value lead to potentially inaccurate estimations.1.

Naim Alkhouri, MD: Using AGILE Scoring to Estimate MASLD Fibrosis, Cirrhosis

The following is a summary of “Treatment of lichen sclerosus with hydroxychloroquine: a Mayo Clinic experience,” published in the July 2024 issue of Dermatology by Akpala et al. Limited study exists on hydroxychloroquine’s efficacy in treating anogenital and extragenital lichen sclerosus, conditions associated with increased scarring and cancer...

Efficacy, Response Rates, and Adverse Effects of Hydroxychloroquine for Anogenital Lichen Sclerosus

A new study found that older patients with atrial functional mitral regurgitation who underwent mitral valve surgery had significantly better outcomes than those who received medical management alone, including lower rates of heart failure hospitalization and death. Patients with atrial functional mitral regurgitation (AFMR) who undergo mitral valve (MV) surgery...

Surgery Improves Outcomes for Patients With Atrial Functional Mitral Regurgitation

Summary: Johns Hopkins Kimmel Cancer Center researchers have developed Esopredict, a PCR-based test that helps gastroenterologists assess the risk of Barrett’s esophagus progressing to esophageal cancer. Takeaways:. Personalized Risk Assessment: The Esopredict test analyzes DNA methylation changes to help determine a patient’s likelihood of progressing from Barrett’s esophagus to...

New PCR Test Enhances Risk Assessment for Barrett’s Esophagus Progression

Denver, CO

In addition to collecting more than 8,000 used needles in the past year from Denver drug users, the Harm Reduction Action Center passed out 10,000 meth pipes and “snort kits,” according to a newsletter sent to its supporters Thursday. They also connected about 1,700 people to medical, mental health and substance abuse treatment.

Denver group hands out 10K meth pipes, ‘snort kits,’ connects 1,700 to treatment annually

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Cooking With Maryann

This recipe is sooo tasty! It truly is for garlic lovers! It involves sautéing onions and mushrooms in butter and oil until golden, then adding wine to reduce. Garlic, thyme, and parsley are stirred in for flavor, followed by seasoning with salt and pepper. The dish is garnished with additional parsley and served warm, making for a savory, aromatic side. Here's what you'll need to make it:

Garlic Mushrooms in Brown Butter Herb Sauce

South Carolina State

Colleton County, SC

Explore Beaufort SC

Some beachgoers were in for a surprise this week when a bizarre looking prehistoric fish washed ashore in Colleton County along Edisto Beach at Edisto Beach State Park. It turned out to be an atlantic sturgeon.

Rare Atlantic sturgeon washes ashore on South Carolina beach

Acute Intermittent Porphyria (AIP) is a rare genetic disorder that affects the production of heme, a vital component of hemoglobin. This condition can cause severe abdominal pain, vomiting, and neurological issues. AIP often goes undiagnosed due to its varied symptoms, which can mimic other illnesses. Understanding this disorder is crucial for those affected and their families. This blog post will provide 30 facts about Acute Intermittent Porphyria to help you grasp its complexities. From its genetic roots to treatment options, these facts will shed light on this mysterious condition. Ready to learn more? Let's dive in!

30 Facts About Acute Intermittent Porphyria

Kentucky State

Northern Kentucky Tribune

Gov. Andy Beshear sent a letter to Anne Milgram, administrator for the U.S. Drug Enforcement Administration (DEA) on Wednesday, expressing his support of the U.S. Department of Health and Human Services’ recommendation that the DEA ease restrictions on marijuana.

Gov. Andy Beshear pens letter to DEA in support of easing federal restrictions on marijuana

July 23, 2024 - Many Americans taking Proton Pump Inhibitors (PPIs) to manage acid reflux may be unaware of a significant side effect: chronic fatigue. Recent findings have highlighted the connection between PPI use and vitamin B12 deficiency, which can lead to persistent tiredness and other health issues.

Proton Pump Inhibitors Linked to Fatigue Due to Vitamin B12 Deficiency

NewsBreak

Givlaari safe, effective for acute hepatic porphyria: Real-world data

Givlaari (givosiran) safely led to a complete resolution of annual attacks in people with acute hepatic porphyria (AHP), according to real-world data from a case series...

Givlaari safe, effective for acute hepatic porphyria: Real-world data

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