Columbus, OH

The Conversation UK

Scientists in America have developed a nasal spray that can remove proteins in the brain associated with Alzheimer’s disease – at least, in mice. There are two proteins implicated in Alzheimer’s: amyloid and tau. Most of the drugs – included those recently approved by the US Food and Drug Administration (FDA) – focus on removing amyloid. To date, though, there has been little focus on removing tau “tangles”. However, the new nasal spray, developed by researchers at the University of Texas Medical Branch, focuses on this protein.

Nasal spray clears proteins linked to Alzheimer’s – new study

In the intricate architecture of​ the human ⁢brain, the emergence of Alzheimer’s disease often heralds a disheartening reality: a gradual and relentless‌ dismantling of memory,⁣ cognition, and identity. Yet, ⁣amidst ‌the shadows ‍cast by this formidable condition, ‍a new ray of ⁤hope has surfaced from the⁣ depths of‍ neuroscience research. ‌Recent studies are unveiling the intriguing relationship between dopamine—a neurotransmitter central to our ⁤feelings ‌of pleasure and reward—and the notorious brain plaques that characterize ‍Alzheimer’s. The idea​ that‍ this chemical messenger ‌could play a‍ pivotal role in dissolving harmful amyloid-beta plaques not only sparks ⁣curiosity but⁢ ignites a potential breakthrough in our understanding of neurodegenerative diseases. In this exploration, ​we delve⁢ into the science ‍behind dopamine’s unexpected therapeutic promise and the implications it holds for combating one ⁣of humanity’s most pressing health⁤ challenges. Join us as we unravel the layers of this complex puzzle, highlighting a⁣ path that may lead to a future where Alzheimer’s is no longer a looming specter but a challenge​ we can confidently confront.

Melting Away Alzheimer’s: How Dopamine Dissolves Harmful Brain Plaques

Blood tests that can detect 90% of Alzheimer’s cases could revolutionize access to Alzheimer’s treatment, studies say.

Alzheimer’s blood test catches 90% of early dementia cases, study finds

Stanford, CA

Neuroscientists at Stanford have linked Alzheimer’s disease to the disruption of brain metabolism via the kynurenine pathway, which is affected by amyloid plaque and tau proteins. Their research has demonstrated that drugs blocking this pathway can restore cognitive function in Alzheimer’s mice by improving brain metabolism. This discovery not...

Stanford Reverses Cognitive Decline in Alzheimer’s With Brain Metabolism Drug

It's natural to experience some cognitive decline as we age, but not all cognitive deficits are a result of dementia. There are a variety of hormonal conditions and nutrient deficiencies that can present similar symptoms. If you’re having trouble concentrating or experiencing some memory loss, don’t panic just yet—rule out...

3 Conditions That Cause Cognitive Decline (But Aren't Dementia)

shefinds

Supplements are often touted as a way to enhance overall health, but not all are created equal. While many supplements can offer benefits, some may inadvertently contribute to cognitive decline. Certain supplements, especially when taken in excess or without proper guidance, can interfere with brain function and mental clarity. It’s crucial to understand how specific supplements might affect cognitive health and to approach supplementation with informed choices.

7 Unexpected Supplements That May Actually Be Leading To Cognitive Decline, According To Experts: Folic Acid & More

Although the overall use of benzodiazepines does not appear to increase the risk of dementia, long-term use is associated with a reduction in the volume of critical brain areas, such as the hippocampus and the amygdala, according to new research published in BMC Medicine. This finding supports current medical guidelines that caution against prolonged benzodiazepine use.

Long-term benzodiazepine use linked to shrinkage in two brain regions

People often use the terms “Alzheimer’s disease” and “dementia” interchangeably, as if they were the same thing. In fact, Alzheimer’s is just one form of dementia. To put it another way, all Alzheimer’s is dementia, but not all dementia is Alzheimer’s. Just as diabetes has types 1 and 2, so does dementia have varying types, of which Alzheimer’s is one. Although all types of dementia are marked by a basic similarity in symptoms—cognitive decline—they vary in terms of causes, physiology, progression, and specific symptoms. People conflate Alzheimer’s with the umbrella term “dementia” because it’s the best-known and most often talked-about form of dementia. This is because it’s the most common form.

What’s the Difference Between Alzheimer’s and Dementia?

New York Post

Neurologist Kim Johnson Hatchett has one recommendation for folks who want to keep their brains functioning now and as they age — build strength. 

Hatchett, who has nearly 9,000 TikTok followers, imparted her advice to keep moving for the sake of your body and brain in a recent post, “The scariest thing I see as a neurologist is the gradual weakening of America. Not moving your muscles . . . has an effect on every aspect of your life and most importantly your brain.”



In an interview this week with Self, Hatchett shared how physical activity is more tightly linked to...

I’m a neurologist — this is the scariest thing people do to their brains

A new study substantiates the link between untreated high blood pressure and an increased risk of Alzheimer’s disease for adults 60 and older. 

The research, published Wednesday in the online issue of Neurology, the medical journal of the American Academy of Neurology, is a review of 14 international studies involving 31,250 people.

Participants, who were 72 years old on average, were followed for around four years for cognitive changes and dementia diagnoses.





Of the contingent studied, 1,415 developed Alzheimer’s disease.

Why your body is going through devastating changes at these two ages: Stanford study

Researchers found that participants with untreated high blood pressure had an increased...

Common condition linked to a 36% higher risk for Alzheimer’s disease

Alzheimer’s disease treatments aim to address symptoms such as memory loss, cognitive decline, difficulty with daily activities, and behavioral changes. While there is no current cure for Alzheimer’s disease, several medications can help manage symptoms and possibly slow its progression. Researchers are also exploring experimental treatments and off-label...

A Guide for Alzheimer’s Treatment Options

rolling out

High blood pressure, also known as hypertension, is a silent but serious health condition that affects millions of people worldwide. Despite its prevalence, many individuals underestimate the dangers associated with untreated hypertension. One of the most severe consequences of refusing to take prescribed blood pressure medication is the increased risk of stroke. In this article, we will explore why managing blood pressure is crucial, the potential outcomes of neglecting medication, and the link between hypertension and stroke. By understanding these risks, individuals can make informed decisions about their health and the importance of adhering to medical advice.

Why refusing to take blood pressure medication might lead to stroke

HuffPost

"What affects your heart will affect your brain, and we see that time and time again,” one expert noted.

Dementia Researchers Discover 2 New Dementia Risk Factors — Here's What They Are

Woman's World

Imagine a simple blood test that could reveal if you’re at risk for Alzheimer’s disease, years before symptoms become severe. A new study shows that this could be a reality. For those at risk, this breakthrough could mean an earlier and more accurate diagnosis. And if accurate blood tests are used, wait times for treatment ...

New Alzheimer’s Test Shows 90% Accuracy in Diagnosing Early-Stage Dementia—Who Should Get It and When

Health

Medically reviewed by Brigid Dwyer, MDMedically reviewed by Brigid Dwyer, MDDementia is a broad term that describes the loss of cognitive abilities like thinking, remembering, using language, and making decisions. Lewy body dementia (LBD) is one type of dementia, named after the scientist who discovered this variation. This type of dementia is thought to be caused by a buildup of a specific protein in the brain.  There are two types of LBD: dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD). In general, both types of LBD are caused by the same accumulation of protein in the brain and...

Signs and Symptoms of Lewy Body Dementia

Everyday Health

Hypoglycemia symptoms include having anxiety, emotional instability, dizziness, and lightheadedness. Here's a list with more signs to watch for.

10 Warning Signs of Low Blood Sugar

LiveScience

Scientists found that two brain-made chemicals, including oxytocin, may play a role in increasing blood pressure after repeated periods of low oxygen.

'Love hormone' oxytocin may be missing link between sleep apnea and high blood pressure

Los Angeles, CA

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Herbie J Pilato

Adam Rich was born on October 12, 1968, lived a troubled life, and died on January 7, 2023, at only 54 years old. This is his story. He lived in the Granada Hills area of Los Angeles with his parents and younger brother. The Rich family resided for a time in Florida where Adam studied acting at the local gym.

A Look Back at the Tragic Life and Death of Former Child Star Adam Rich (TV's 'Eight is Enough')

The genetic risk of developing Alzheimer’s disease is more strongly influenced by the mother’s side than the father’s side, a recent study has discovered. Alzheimer’s disease steals memories, independence and the capacity to connect with loved ones. In 2020, over 55 million people worldwide were living with dementia. Alzheimer’s disease is the most common form of dementia, accounting for 60-70% of all dementias.

Maternal genetics play bigger role in Alzheimer’s risk, study finds

Zyn pouches are the latest nicotine craze in the world of cigarette substitutes. They're touted as a panacea for addiction to smoking and vaping. Philip Morris boasts selling more than 130 million containers in the first quarter of this year. But health experts and government officials are looking to crackdown on the sale of these pouches.

A drug that restores brain metabolism could help treat Alzheimer's

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