Opioid receptors located in the dorsal peduncular nucleus uniquely contribute to the rewarding effects of opioids. Opioids, such as the widely prescribed painkiller oxycodone, are notorious for their high addiction potential. In 2022, opioid overdoses claimed the lives of nearly 85,000 people in the U.S., as reported by the Centers for Disease Control. Despite this, opioids continue to be prescribed at concerning rates, especially in Southern states, largely due to the scarcity of effective alternatives.

Scientists Uncover Hidden Mechanism Behind Opioid Addiction – Discovery Could Revolutionize Addiction Treatment

About The Study: In this longitudinal cohort study of economically and racially diverse U.S. youth, there was evidence of differential susceptibility and resilience for mental health problems during the pandemic that was associated with prepandemic mental health and sociodemographic characteristics. These differences are critical to understand for recovery and may yield novel insights into causes of youth mental health problems.

Longitudinal changes in youth mental health from before to during the COVID-19 pandemic

Roughly a third of all Americans will experience an anxiety disorder at some point in their lives. While leading anti-anxiety medications are generally effective and well-tolerated, they come with problematic drawbacks. In a new study, researchers discovered a signaling pathway that when slowed down via a therapeutic injection, effectively halted anxious behaviors in mice.

Researchers discover an entirely new way to treat anxiety

Picture this scene: You’re lying wide awake at 2 a.m. despite having gone to bed four hours earlier. You toss and turn. But no matter what sleep position you attempt or how many guided meditations you listen to, you just can’t catch a break. Maybe that post-dinner espresso...

Could Xanax Actually Help You Sleep?

Health

Medically reviewed by Aleesha Grier, PsyDMedically reviewed by Aleesha Grier, PsyDAttention-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BD) are two separate mental health conditions that affect behaviors and daily life. ADHD is a behavioral disorder that causes problems with attention, hyperactivity, and impulsive actions. BD is a mood disorder that causes episodes of manic highs and depressive lows. ADHD and BD conditions share similar symptoms, but there are key differences, such as the available treatment options.Symptoms of ADHD vs. Bipolar DisorderADHD and bipolar disorder share some common symptoms. For example, they both affect a person’s ability to pay attention and concentrate. This...

How To Tell the Difference Between ADHD and Bipolar Disorder

Real Housewives of Dubai star Caroline Stanbury revealed that she “projectile vomited” at a bar while she was on Ozempic. Nausea, vomiting, diarrhea, and upset stomach are side effects associated with Ozempic and can become worse when the medication is combined with alcohol. However, research shows that Ozempic...

‘Real Housewives’ Star Says Drinking Alcohol While on Ozempic Made Her ‘Projectile Vomit’

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Total Apex Sports & Entertainment

Virgo season will progress well on August 27. Three struggling zodiac signs will tap Gemini’s immense energy which will help them end their grief. The Half Moon will test their resolve to heal and desire to continue facing hardships. Still, Gemini’s healing vibe will inspire them to end their hardships and change existing circumstances.

3 Zodiac Signs Whose Hardships End on August 27, 2024

Over 12,000 feet below the surface of the sea, in a region of the Pacific Ocean known as the Clarion-Clipperton Zone (CCZ), million-year-old rocks cover the seafloor. These rocks may seem lifeless, but nestled between the nooks and crannies on their surfaces, tiny sea creatures and microbes make their home, many uniquely adapted to life in the dark.

Marine science oxygen produced in the deep sea raises questions about extraterrestrial life

The FDA approved Zurnai, the first nalmefene hydrochloride auto-injector for the emergency treatment of known or suspected opioid overdose in adults and pediatric patients 12 years of age and older. The agency approved the first nasal spray formulation of nalmefene in May 2023. Drug overdose persists as a major public...

FDA Approves First Nalmefene Hydrochloride Auto-Injector to Reverse Opioid Overdose

Coffee County, GA

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Daily Coffee Press

Last week, two individuals from Coffee County were charged with trafficking methamphetamine following a search at a residence on Willacoochee Highway. On August 13, detectives with the Coffee County Drug Unit conducted an operation involving Charles Black, which led to a search of his residence on Willacoochee Highway. According to the report, Black left his residence before the warrant was served and was subsequently detained.

Two Charged with Trafficking Methamphetamine After Search in Coffee County

A new scientific review of 148 studies enrolling over 4.3 million adult chronic pain patients treated with prescription opioid painkillers has found that nearly one in ten patients experiences opioid dependence or opioid use disorder and nearly one in three shows symptoms of dependence and opioid use disorder. This review provides a more accurate -- and more concerning -- rate of opioid misuse than has previously been calculated. It was conducted by researchers at the University of Bristol, funded by the National Institute for Health and Care Research (NIHR), and appears in the scientific journal Addiction.

Prescription Painkiller Misuse in Chronic Pain Patients

About The Study: Patients with post–COVID-19 mRNA vaccination myocarditis, contrary to those with post–COVID-19 myocarditis, show a lower frequency of cardiovascular complications than those with conventional myocarditis at 18 months. However, affected patients, mainly healthy young men, may require medical management up to several months after hospital discharge.

Long-term prognosis of patients with myocarditis attributed to COVID-19 mRNA vaccination, SARS-CoV-2 infection, or conventional etiologies

Tracey Tee, 48, and her business partner spent nearly a decade building a successful brand and traveling across the country performing parent-focused comedy sets. "And then Covid [and] the lockdowns happened," she says. "Within two weeks, we had to cancel nearly 100 shows for 2020, and lost everything. Almost a 10-year business just slipped through our fingers like sand. And the grief of that, especially what felt like an epic failure that just wasn't our fault, was intense and then compounded with the lockdown."

48-year-old founded 'Moms on Mushrooms' to share the practice of microdosing for mental health

Chemotherapy is a type of cancer treatment that uses medications to kill fast-growing cancer cells. Depression may be one of the possible side effects of chemotherapy. Chemotherapy medications travel through the body and can mistakenly attack and damage healthy cells. This can leave a person with several side effects, which can be painful, change a person’s appearance, and affect their mood.

Chemotherapy and depression: Is there a connection?

South Carolina State

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Florida State

Akeena

Recent data from the U.S. Census Bureau reveals a significant trend: Florida is experiencing a substantial outflow of residents. According to the latest figures, over 275,000 individuals left Florida for other states in 2022.

Florida Sees Surge in Departures as Hundreds of Thousands Move Out

New York City, NY

NEW YORK, NY (AUGUST 26, 2024) — A team of scientists from The New York Stem Cell Foundation (NYSCF) Research Institute and Case Western Reserve University has created the largest reported collection of stem cell models from multiple sclerosis (MS) patients and used them to identify unique ways in which glia – integral support cells in the brain – contribute to the disease.

Human stem cell models point to glia as key players in multiple sclerosis

The Lens

This year’s area of low oxygen in the Gulf of Mexico is larger than average, the National Oceanic and Atmospheric Administration (NOAA) announced on Thursday. The “dead zone” is approximately 6,705 square miles , as measured last week. Within NOAA’s 38 years of measuring the dead zone, this year’s assessment marks the 12th-largest area of low to no oxygen, which can kill fish and marine life.

Gulf ‘dead zone’ larger than average, larger than expected for 2024, scientists announce

LA JOLLA, CA—Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify proteins—and their specific parts—that future drugs should target. But when used on their own, past approaches haven’t been detailed enough to spotlight all potential protein targets, leading to some being missed.

New way to potentially slow cancer growth

Gillian May

I’m a former nurse and recovering alcoholic, and I’ve been concerned by the lack of health education given to the general public about the dangers of mixing alcohol with certain medications. The common practice is to place warnings on medications that they should not be combined with alcohol. Although some doctors will provide warnings and some education, they often don’t because education takes up a lot of time in a busy healthcare environment. Plus, many doctors underestimate the ability of patients to retain education. Lastly, discussing this may prompt people to stop taking their vital medications so it becomes a risk/benefit issue.

Opinion: Why You Shouldn’t Mix These Medications With Alcohol

Colorado State

David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

NewsBreak

Could psychedelic-assisted therapy change addiction treatment?

PISCATAWAY, NJ – After years of being seen as dangerous “party drugs,” psychedelic substances are receiving renewed attention as therapies for addiction -- but far more...

Could psychedelic-assisted therapy change addiction treatment?

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