Solly Chedid, MD, presents a patient case and provides clinical insights on approaching first-line therapy selection in patients with LR-MDS and moderate to severe anemia. Case: Frontline Use of Erythroid Maturating Agent (EMA): Luspatercept. Clinical Presentation:. 70-year-old man diagnosed 6 months ago with LR-MDS with multilineage dysplasia - moderate anemia...

Approach to 1L Therapy Selection in Lower-Risk MDS

Mikkael A. Sekeres MD, MS, discusses transfusion independence rates with imetelstat in patients with low- to intermediate-1 risk myelodysplastic syndromes. Mikkael A. Sekeres MD, MS, professor of medicine and chief of the Division of Hematology, Leukemia Section at the University of Miami Health System, Sylvester Comprehensive Cancer Center, discusses transfusion independence rates with imetelstat (Rytelo) in patients with low- to intermediate-1 risk myelodysplastic syndromes (MDS).

Transfusion Independence Sustained With Imetelstat in Low-Risk MDS

Everyday Health

Fatigue, feeling dizzy or out of breath, and headaches are some of the most common signs of anemia, a blood disorder in which the body lacks sufficient levels of red blood cells.

12 Most Common Symptoms of Iron-Deficiency Anemia

Review of: Risk of nonarteritic anterior ischemic optic neuropathy in patients prescribed semaglutide. Hathaway J, Sha M, Hathaway D, et al. JAMA Ophthalmology, in press 2024. Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) prescribed to assist with weight management in patients with type 2 diabetes (T2D) or those who are overweight/obese, and there have been anecdotal reports of nonarteritic anterior ischemic optic neuropathy (NAION) in patients taking this medication. This single-center, observational study compared patients prescribed semaglutide to matched patients prescribed other medications for diabetes and found a greater risk of NAION in the semaglutide cohort, though additional studies are needed to verify this relationship and causality cannot be inferred.

Semaglutide May Be Associated With an Increased Risk of Developing NAION

Heavy or prolonged periods can cause iron deficiency anemia. Anemia may impact periods, but this requires further research. Iron deficiency anemia occurs if people do not have enough iron in the body for it to make healthy red blood cells. Heavier or longer periods can cause iron deficiency anemia. This...

What to know about anemia and periods

A complete blood count, chemistry profile, immunoglobulin test, and light chain assay are among the important blood tests doctors use to help diagnose multiple myeloma. Multiple myeloma is a type of cancer that affects the white blood cells that your bone marrow produces. Doctors can help diagnose multiple myeloma using...

How Do Blood Tests Help in Multiple Myeloma Diagnosis?

Different blood tests, including a complete blood count (CBC), iron test, or B12 test, can help diagnose anemia, which can have different causes. Anemia occurs when there are not enough healthy red blood cells or hemoglobin in the blood to transport oxygen to cells. A CBC can reveal if a...

Anemia blood test: Types and results explained

If you are an adult living with kidney disease and excess weight or obesity, you may be eligible to join a trial studying the impact of tirzepatide on kidney function. Trial Name: Tirzepatide Study of Renal Function in People With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes: Focus on Kidney Hypoxia in Relation to Fatty Kidney Disease Using Multiparametric Magnetic Resonance Imaging (TREASURE-CKD)

New Trial Studying Tirzepatide for Chronic Kidney Disease

Health

Medically reviewed by Jay N. Yepuri, MDMedically reviewed by Jay N. Yepuri, MDLiver function blood tests are tests that detect how well your liver is working. Your liver is an important organ that performs key roles, such as metabolizing fats and proteins, removing toxins from your blood, synthesizing proteins, and regulating red blood cells.Liver function tests (LFTs) can also measure the levels of different liver enzymes, proteins, and bilirubin in the blood. High or low levels of these substances may be a sign that your liver isn't functioning as properly as it should.Liver function tests are also helpful because they...

What To Expect During a Liver Function Blood Test

Moderate to severe anemia was linked to an increase in cardiac arrest or stroke compared with normal hemoglobin levels in critically ill COVID-19 patients. Moderate-to-severe anemia was linked to an elevated risk of cardiac arrest or stroke, compared with a normal hemoglobin (Hb) level, in an international registry of patients with acute COVID-19 infection in the intensive care unit (ICU).1.

Anemia Increases Cardiac Arrest, Stroke Risk in COVID-19 Admissions

In the European Journal of Case Reports in Internal Medicine, physicians discussed the case of a patient with paroxysmal nocturnal hemoglobinuria (PNH) that presented as Plasmodium falciparum infection. A 27-year-old man was admitted for fever and chills, chronic fatigue, dyspnea, and chest pain. His past medical history included chronic anemia...

Case Report: PNH Can Make Patients With PNH Susceptible to Parasitic Infection

Research on over 24,000 men revealed that low testosterone levels significantly increase the risks of death from all causes and cardiovascular issues, underlining the hormone’s impact on aging men’s health. A systematic review and meta-analysis revealed that men with low baseline levels of endogenous serum testosterone face a...

Low Testosterone in Men Linked to Increased Risk for Death

Hypoglycemia symptoms include having anxiety, emotional instability, dizziness, and lightheadedness. Here's a list with more signs to watch for.

10 Warning Signs of Low Blood Sugar

The following is a summary of “Kidney volume and risk of incident kidney outcomes,” published in the June 2024 issue of Nephrology by Wu et al. Low total kidney volume (TKV) increases the risk of chronic kidney disease (CKD). Researchers conducted a prospective study investigating the nonlinear relationships,...

Lower Kidney Volume Linked to Increased Risk of Incident CKD

A genetics-based platelet reactivity score can help identify people with a hyperreactive platelet phenotype who may have increased risk for a cardiovascular event, according to research published in Nature Communications. In two high-risk cohorts, researchers reported an association between an above-median Platelet Reactivity Expression Score (PRESS) and increased risk for...

Top in cardiology: Platelet score predicts heart trouble; chronic noise and hypertension

Acute kidney injury, when the kidneys suddenly stop working properly, impacts many with diabetes. Here’s what to know about the condition, which is usually reversible. Acute kidney injury (AKI) is a sudden decline in kidney function. The condition is different from chronic kidney disease (CKD), but occurs more frequently...

Acute Kidney Injury: Causes, Treatment, and Prevention

The MACI Arthro can be administered through small incisions using custom instruments to repair cartilage defects in the knee. The FDA has approved Vericel Corporation’s MACI for repairing cartilage defects in the knee. According to the company, MACI uses a patient’s own cells cultured on a porcine collagen membrane. This method, also known as MACI Arthro, can be administered through small incisions using custom instruments, providing a substantial improvement in full-thickness cartilage defects up to 4 cm² in size, offering a less invasive option, according to the company.1.

FDA Approves Arthroscopic Delivery of Vericel’s MACI for Knee Cartilage Defects

This is the first installment of a 6-part series on the management of polycystic ovary syndrome (PCOS). In this installment, Danielle R. Stratton, DNP, RN, PPCNP-BC, will discuss the basics of the syndrome and the psychosocial impact it can have from diagnosis to later life. Polycystic ovary syndrome (PCOS) is...

Polycystic Ovary Syndrome: Psychosocial Effects

Among patients with fibromyalgia, there was a moderate negative correlation between vitamin D and physical functioning as well as between magnesium and stiffness. An exploratory study evaluating the link between specific micronutrients and the symptoms of fibromyalgia revealed vitamin D and magnesium played a role in physical function and stiffness among patients.1.

Vitamin D, Magnesium Deficiency Linked to Worse Fibromyalgia Symptoms

LiveScience

Women with severe endometriosis are 10 times more likely to get ovarian cancer, while people with endometriosis of any severity are four times as likely, a study suggests. But patients shouldn't panic.

Endometriosis may quadruple risk of ovarian cancer, study finds

NewsBreak

Key Takeaways and Unmet Needs in Lower-Risk MDS Anemia Management

Solly Chedid, MD, shares insights on optimizing anemia management in patients with lower-risk MDS and outlines remaining unmet needs in treating anemia. Case: Frontline Use of...

Key Takeaways and Unmet Needs in Lower-Risk MDS Anemia Management

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