Columbus, OH

Although the overall use of benzodiazepines does not appear to increase the risk of dementia, long-term use is associated with a reduction in the volume of critical brain areas, such as the hippocampus and the amygdala, according to new research published in BMC Medicine. This finding supports current medical guidelines that caution against prolonged benzodiazepine use.

Long-term benzodiazepine use linked to shrinkage in two brain regions

Restoring the energy supply of nerve cells in the brain by activating a gene called PGK1 — which encodes an enzyme of the same name — could help protect these cells from damage and thus prevent Parkinson’s disease from developing or progressing over time, according to a new study in mice.

Restoring energy supply may protect brain cells in Parkinson’s

Summary: Researchers have uncovered how the neocortex and thalamus work together to detect discrepancies between expected and actual sensory events, revealing key insights into brain function. By selectively amplifying unexpected sensory input, the brain generates prediction error signals crucial for learning and adaptation. This discovery could lead to a better...

How the Brain Detects Surprises

New Haven, CT

More than two decades ago, a research team in the lab of David Hafler, a Yale researcher who at the time was at Harvard, discovered a type of T cell in humans that suppresses the immune system; they later found that these so-called regulatory T cells, when defective, are an underlying cause of autoimmune disease, specifically multiple sclerosis (MS). For many years, however, the mechanism behind this dysfunction has remained unclear.

Study reveals molecular mechanism behind MS and other autoimmune diseases

A major study using brain MRIs from over 31,000 adults suggests that type 2 diabetes and prediabetes may lead to accelerated brain aging. Those with diabetes, especially when uncontrolled, showed brains that were significantly older than their chronological age. However, lifestyle choices like exercise and avoiding smoking and excessive drinking may mitigate these effects.

Diabetes Can Accelerate Brain Aging – New Study Shows How To Stop It

Findings from a recent study analyzing 3 cohorts suggested that certain proteins in the cerebrospinal fluid may have potential as biomarkers or therapeutic targets in progressive supranuclear palsy. A recent cross-sectional study using DNA slow off-rate modified aptamers (SOMAmers) proteomics demonstrated that axon guidance pathway proteins and various other molecular...

Axon Guidance Pathway Proteins Identified as Potential Biomarkers for Progressive Supranuclear Palsy

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Total Apex Sports & Entertainment

Virgo season will progress well on August 27. Three struggling zodiac signs will tap Gemini’s immense energy which will help them end their grief. The Half Moon will test their resolve to heal and desire to continue facing hardships. Still, Gemini’s healing vibe will inspire them to end their hardships and change existing circumstances.

3 Zodiac Signs Whose Hardships End on August 27, 2024

Everyday Health

Spoon-shaped nails and a swollen, smooth tongue are unusual signs of iron deficiency. Learn more about the other odd signs of low iron levels.

7 Weird Signs of Iron Deficiency

Fatigue, feeling dizzy or out of breath, and headaches are some of the most common signs of anemia, a blood disorder in which the body lacks sufficient levels of red blood cells.

12 Most Common Symptoms of Iron-Deficiency Anemia

Summary: Researchers have developed an innovative device that can diagnose glioblastoma, an aggressive brain cancer, in under an hour using a novel biochip. The chip leverages electrokinetic technology to detect active Epidermal Growth Factor Receptors (EGFRs) in extracellular vesicles from a small blood sample. This method offers high sensitivity and...

Blood Sample Allows for Rapid Detection of Brain Cancer

People often use the terms “Alzheimer’s disease” and “dementia” interchangeably, as if they were the same thing. In fact, Alzheimer’s is just one form of dementia. To put it another way, all Alzheimer’s is dementia, but not all dementia is Alzheimer’s. Just as diabetes has types 1 and 2, so does dementia have varying types, of which Alzheimer’s is one. Although all types of dementia are marked by a basic similarity in symptoms—cognitive decline—they vary in terms of causes, physiology, progression, and specific symptoms. People conflate Alzheimer’s with the umbrella term “dementia” because it’s the best-known and most often talked-about form of dementia. This is because it’s the most common form.

What’s the Difference Between Alzheimer’s and Dementia?

NewsNinja

‘Any meat items my dogs refuse to eat, I no longer eat.’ It’s said that animals have a “sixth sense,” which affords them an insight human beings cannot match. There are clips of security camera earthquake footage where pets can be seen wigging out seconds before tremors begin.

‘It ain’t food anymore.’: Dairy Queen customer warns against chicken after his dog refuses to eat it

Multiple sclerosis (MS) is a chronic autoimmune disease — one in which the body erroneously attacks itself — that affects the central nervous system. Specifically, MS develops when the immune system attacks myelin, a fatty substance that makes up a protective coating around nerve fibers called the myelin sheath. This can result in a variety of symptoms that vary between people, ranging in severity from mild to disabling.

Diagnosed With Multiple Sclerosis — What Should I Do Now?

Lewy Body Dementia (LBD), sometimes called Dementia with Lewy Bodies, is the third most common form of dementia (after Alzheimer’s disease and vascular dementia), affecting approximately 1.3 million American adults and accounting for up to 30% of dementia cases. Like Alzheimer’s and vascular dementia, LBD is progressive and irreversible, and is marked by mental decline. It often occurs alongside other forms of dementia.

What is Lewy Body Dementia?

Women with vs. without cognitive impairment had more intense menopause symptoms. Lower BMI, sexual activity, exercise, hormone therapy use and higher education were tied to lower cognitive impairment odds. Severe menopause symptoms, such as hot flashes and depressive mood, were associated with mild cognitive impairment for postmenopausal women, researchers reported...

Severe menopause symptoms linked to cognitive impairment in later life

Cancer Health

Psychedelic drugs such as psilocybin cause acute changes in how people perceive time, space, and the self. In ongoing experimental research, a single psilocybin dose under controlled conditions is showing promise for relieving mental health symptoms such as depression. These therapeutic effects can last long after the acute effects of the drug wear off. But it’s not clear how these drugs affect the workings of the brain and lead to the drugs’ therapeutic effects.

How Psychedelic Drugs Alter the Brain

Massachusetts State

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Dianna Carney

Sandy Paws Rescue Inc., a foster-based rescue in Massachusetts, has recently introduced an adorable dog named Sushi who is looking for her forever home. Sushi is a 2-3 year-old, 49lb American bully with a friendly demeanor and a love for people. According to Sandy Paws Rescue Inc., "Sushi is friendly with all people she meets! She is fostered with a high energy smaller dog and a cat, and is doing well with both (mostly ignores them—she’s more focused on her people!)."

Meet Sushi: The Loving Dog Who Was Severely Neglected Now Looking For Love

IMU-838 daily doses of 30-mg and 45-mg suppressed the development of gadolinium-enhancing lesions by 78% and 74% compared with the placebo at 24 weeks in relapsing-remitting multiple sclerosis. New data from the phase 2 EMPhASIS trial (NCT03846219) published in Neurology Neuroimmunology & Neuroinflammation showed that vidofludimus calcium formulation (IMU-838) given...

IMU-838 Shows Reduction of Brain Lesions in Phase 2 EMPhASIS Trial for Relapsing-Remitting Multiple Sclerosis

The Marijuana Herald

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According to researchers at the University of Bonn and the Hebrew University of Jerusalem, the long-term, low-dose administration of tetrahydrocannabinol (THC) can reverse aging processes in the brain and may have broader anti-aging effects. The study, recently published in the journal ACS Pharmacology & Translational Science, sheds light on the complex role of the protein … 
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Study Finds THC Reverses Brain Aging and Enhances Cognition in Animal Model

Medical News Today

Researchers identified an enzyme that regulates glucose metabolism in the brain and discovered that a cancer drug may help treat early-stage Alzheimer's. Treatment with the cancer drug restored function in the hippocampus in an Alzheimer's mouse model.

Could a cancer drug help treat early Alzheimer’s? Study offers clues

NewsBreak

Study Links Gene Variations to Brain Changes in Essential Tremor

Summary: Researchers identified how gene variations lead to brain changes associated with essential tremor, a common movement disorder affecting over 60 million people worldwide. The study...

Study Links Gene Variations to Brain Changes in Essential Tremor

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