Columbus, OH

Topline results from the Phase III V-MONO study of Leqvio found that twice-yearly Leqvio achieved clinically LDL-C lowering compared to both placebo and ezetimibe. Results from the Phase III V-MONO trial found that Novartis’ Leqvio (inclisiran) demonstrated noteworthy LDL-C reduction as a monotherapy in patients at low to moderate risk of atherosclerotic cardiovascular disease (ASCVD). According to the company, this is the first study to evaluate a small interfering RNA (siRNA) therapy for LDL-C reduction in this patient population. Additionally, results indicated that twice-yearly Leqvio achieved clinically meaningful and statistically significant LDL-C lowering compared to both placebo and ezetimibe in patients not on other lipid-lowering therapies.1.

Leqvio Demonstrates Significant LDL-C Reduction in Patients at Risk of Atherosclerotic Cardiovascular Disease

HELIOS-B trial shows vutrisiran reduces all-cause mortality and CV events in ATTR-CM, with benefits consistent regardless of tafamidis use. The HELIOS-B trial has returned promising results, indicating use of vutrisiran (Amvuttra), a novel RNA interference therapy, could provide significant benefit on both outcomes and quality of life for patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM).

Vutrisiran Reduces Cardiovascular Risk, Improves Quality of Life in ATTR-CM

A single blood test using hsCRP, LDL-C, and Lp(a) levels can predict cardiovascular risk for women up to 30 years, emphasizing personalized care. A single blood test could predict cardiovascular for women for up to 3 decades, according to new research presented at the European Society of Cardiology (ESC) Congress 2024.

Single Blood Test Could Predict Cardiovascular, Stroke Risk in Women for Up to 30 Years

Transcatheter mitral valve repair improved outcomes and symptoms in patients with moderate to severe mitral regurgitation and HF. Prior studies enrolled patients with more severe disease. Perspective from Carlos G. Santos-Gallego, MD; Sean Pinney, MD, FACC, FAST, FHFSA. Transcatheter mitral valve repair in addition to medical therapy led to a...

MitraClip improves outcomes in patients with less severe mitral regurgitation, heart failure

shefinds

Supplements are often taken to improve health and fill nutritional gaps, but not all are as beneficial as they seem. Some supplements, particularly when taken in excess or without proper guidance, can have unintended negative effects. For example, certain supplements can unknowingly contribute to high blood pressure and increase the risk of cardiovascular events.

4 Worst Supplements That Could Actually Lead To High Blood Pressure And Cardiovascular Events: Licorice Root & More

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Total Apex Sports & Entertainment

Big changes are in store for three zodiac signs in the month of September. The stars are shifting and many of you will be affected by this. Although the life changes that will take place with each zodiac sign are different, these changes must be fully embraced by all who are experiencing them. One of the key things to remember is that sometimes change is necessary for personal growth. Let’s see what the stars have in store for these three zodiac signs.

3 Zodiac Signs Whose Lives Will Change In September

There are tens of millions of people in the U.S. taking the cholesterol-lowering medications known as statins to prevent heart disease. This could be because the U.S. Preventative Services Task Force advises healthcare professionals to prescribe statins in patients ages 40 to 75 who have at least one risk factor for heart disease, such as diabetes or dyslipidemia, and an estimated 10-year cardiovascular risk of 10 percent or more.

Glaucoma joins growing list of statin side effects

In the United States, approximately 47% of adults have hypertension, a condition characterized by consistently elevated blood pressure. This statistic is concerning as high blood pressure is a significant risk factor for serious health issues, including heart disease, stroke, and kidney disease. Elevated blood pressure often goes unnoticed due to its asymptomatic nature, earning it the nickname “the silent killer.” Health practitioners must prioritize blood pressure monitoring and management, as early detection and treatment can prevent complications and improve overall health outcomes. By addressing hypertension, practitioners can significantly reduce the burden of cardiovascular diseases and enhance the quality of life for their patients.

9 Effective Ways to Lower Blood Pressure Naturally

LiveScience

Blood clots can be dangerous, especially if all or part of them break off and then travel through the bloodstream.

What causes blood clots?

An aortic root aneurysm is a bulge in the first section of the aorta, where the artery joins the heart and aortic valve. Treatment for an aortic root aneurysm can help prevent serious complications. The aorta is the main artery that transports blood away from the heart to supply the...

What is an aortic root aneurysm?

Georgia State

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Atlanta, GA

Daily Coffee Press

A 40-year-old man has been sentenced to over 28 years in prison for distributing significant amounts of fentanyl and other controlled substances to dealers in the Middle Georgia region. Authorities revealed that investigators uncovered evidence linking the drugs provided by the defendant, 40-year-old Lagary Williams, also known as "Frog," from Atlanta, to a fatal overdose.

Atlanta Man Sentenced to 28 Years for Supplying Deadly Fentanyl Linked to Fatal Overdose

In a head-to-head comparison, drinks containing erythritol, a sweetener in stevia and keto products, raised the risk of blood clots while sugar water did not.

Zero calorie sweetener linked to blood clots and risk of heart disease, study finds

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Shin

Statins are widely recognized for their role in lowering low-density lipoprotein (LDL) cholesterol and reducing the risk of heart disease. But new research from the Cholesterol Treatment Trialists’ Collaboration (CTSU) has revealed that these life-saving medications may come with a small but significant drawback—an increased risk of developing diabetes, particularly in individuals already predisposed to the condition.

Statins and Diabetes: New Comprehensive Research Confirms Elevated Risk

A genetics-based platelet reactivity score can help identify people with a hyperreactive platelet phenotype who may have increased risk for a cardiovascular event, according to research published in Nature Communications. In two high-risk cohorts, researchers reported an association between an above-median Platelet Reactivity Expression Score (PRESS) and increased risk for...

Top in cardiology: Platelet score predicts heart trouble; chronic noise and hypertension

The largest glaucoma diagnosis postponement was seen in the early menopause group (3.6 years) and the smallest observed in the late menopause group (2.7 years). Photo: Schering. Click image to enlarge. Researchers at Atlanta’s Emory University recently investigated ways in which estrogen may aid in delaying development of open-angle glaucoma....

Hormone Therapy in Postmenopausal Women Linked with Later Glaucoma Diagnosis

An abnormal buildup of fat in the liver, referred to as fatty liver disease, was found to be common in a small group of children and adults with spinal muscular atrophy (SMA), regardless of their disease type or severity. Patient-derived liver cells confirmed that such accumulation was a result of...

Fatty liver disease may be common complication of SMA: Small study

Verywell Health

Constipation may increase the risk of heart problems, particularly in people with high blood pressure. Existing research has linked constipation to blood clots and heart disease. Lifestyle changes, such as eating a high-fiber diet and exercising regularly, can improve both constipation and overall health outcomes. Constipation doesn’t only make you...

Constipation Is Linked to a Higher Risk of Heart Problems

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The Best Time of Day To Take Your Blood Pressure Meds To Lower Your Heart Attack Risk, According to Cardiologists

High cholesterol can cause the arteries to narrow, leading to serious complications, such as heart disease, heart attack, and stroke. Lowering high cholesterol can help prevent complications. High cholesterol can lead to excess cholesterol in the blood, which can cause a buildup of fatty deposits, or plaque, in the arteries.

Potential complications of high cholesterol

Research on over 24,000 men revealed that low testosterone levels significantly increase the risks of death from all causes and cardiovascular issues, underlining the hormone’s impact on aging men’s health. A systematic review and meta-analysis revealed that men with low baseline levels of endogenous serum testosterone face a...

Low Testosterone in Men Linked to Increased Risk for Death

NewsBreak

M-TEER Reduces Cardiovascular Risk, Improves Quality of Life in HF with Mitral Regurgitation

RESHAPE-HF2 shows mitral transcatheter edge-to-edge repair (M-TEER) reduces heart failure hospitalizations and improves quality of life vs optimal medical therapy alone. Results of RESHAPE-HF2 suggest use...

M-TEER Reduces Cardiovascular Risk, Improves Quality of Life in HF with Mitral Regurgitation

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