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Long COVID Data Easier to Access
Secure data from more than 14,000 adults who participate in National Institutes of Health (NIH) observational research on long COVID are now available to authorized researchers through BioData Catalyst (BDC). BDC is a cloud-based ecosystem developed by the National Heart, Lung, and Blood Institute (NHLBI), part of the NIH, to accelerate research on heart, lung, blood and sleep disorders.
Prevention: Ultra-Long-Acting PrEP
An ultra-long-acting formulation of cabotegravir may offer an HIV pre-exposure prophylaxis (PrEP) and treatment option that could be administered three times a year. The approved formulation of cabotegravir for PrEP (Apretude) is administered by a health care provider every other month, while cabotegravir plus rilpivirine (Cabenuva) for treatment is given monthly or every other month. In a Phase I trial, the new formulation—dubbed CAB-ULA— given by subcutaneous or intramuscular injection achieved comparable drug exposure levels but lasted longer in the body. Its pharmacokinetic profiles were flatter, indicating slower absorption. Pharmacokinetic modeling predicted that intramuscular CAB-ULA given at least four months apart would achieve higher drug exposure than the current formulation given every two months. CAB-ULA was generally well tolerated. Intramuscular CAB-ULA will now progress to late-stage trials, and more testing of the subcutaneous formulation—which could potentially be self-administered—is planned.
Consequential Scientist
Alison Rodger, MD, is one of the most consequential HIV scientists in the history of the disease. Her research, much of it done at University College London, demonstrated definitively that a person with an undetectable viral load does not transmit HIV via sex. Anecdotal evidence from serodiscordant couples had already...
Add Lemon to Your Water
Adding lemon to your water has many benefits. It helps burn more calories. It also relieves many digestion problems. Lemon’s antiaging properties make it great for the skin. Have a toothache or bad breath? Lemon water can help. If you have tonsil issues, it’s good to gargle lemon water...
Heart of the Matter
Alicia Diggs, MPH, is a busy woman. Currently wrapping up her PhD in public health education, she’s driven by a desire to improve the health care system for women and people of color. A Philadelphia native now residing in Burlington, North Carolina, Diggs splits her time between her academic...
New Effort to Include People With HIV or on PrEP in Clinical Trials [VIDEO]
When clinical trial researchers write their guidelines and decide on eligible participants, most continue to copy and paste outdated boilerplate language from the early days of the AIDS epidemic. As a result, clinical trials exclude people living with HIV as well as those who are HIV negative but take antiretrovirals as pre-exposure prophylaxis (PrEP) to prevent HIV. Similarly, LGBTQ people—also referred to as SGMs for “sexual and gender minorities”—are underrepresented in clinical studies.
Twice-Yearly Lenacapavir PrEP Prevents HIV in Women
The twice-yearly HIV capsid inhibitor lenacapavir demonstrated 100% efficacy for preventing acquisition of the virus in a large study of young cisgender women in Africa, Gilead Sciences announced yesterday. The PURPOSE 1 trial showed that lenacapavir pre-exposure prophylaxis (PrEP), administered by subcutaneous injection once every six months, significantly reduced HIV...
Robert Gallo, Codiscoverer of HIV, Takes His Research to Tampa
Robert Gallo, MD, the influential virologist who codiscovered HIV and developed a test for the virus, will be joining the University of South Florida (USF) faculty as director of a new virology center, according to a USF news release. USF also announced that it will play host to the international...
Learning How to Live and Die With Long COVID
This story was originally published by High Country News. he heady scent of wet creosote hung in the air the morning we skirted impossible alluvial fans on our way to the lowest point in North America. Since the Pleistocene, Badwater Basin, 236 feet below sea level, has primarily been a salt flat, but deluges from Hurricane Hilary and a recent atmospheric river had filled the pan with billions of gallons of water. Lake Manly was a zombie, back from the dead. Many said it was the largest it had been for decades. Pushed by strong winds in March, it even drifted two miles north, like some kind of restless soul.
Biden Leans Into Health Care, Asking Voters To Trust Him Over Trump
Angling to tap into strong support for the sweeping health law he helped pass 14 years ago, one of President Joe Biden’s latest reelection strategies is to remind voters that former President Donald Trump tried to repeal the Affordable Care Act. “Folks, he’s coming for your health care, and...
Americans With HIV Are Living Longer. Federal Spending Isn’t Keeping Up.
Malcolm Reid recently marked the anniversary of his HIV diagnosis on Facebook. “Diagnosed with HIV 28 years ago, AND TODAY I THRIVE,” he wrote in a post in April, which garnered dozens of responses. Reid, an advocate for people with HIV, said he’s happy he made it to...
San Francisco Tries Tough Love by Tying Welfare to Drug Rehab
Raymond Llano carries a plastic bag with everything he owns in one hand, a cup of coffee in the other, and the flattened cardboard box he uses as a bed under his arm as he waits in line for lunch at Glide Memorial Church in San Francisco. At 55, he hasn’t had a home for 15 years, since he lost a job at Target.
Dennis Shares His MDR HIV Treatment Journey
Paid advertisement from ViiV Healthcare. Please note: The content in this testimonial is from a person living with HIV-1 sharing his personal experience about his diagnosis and his treatment with RUKOBIA (fostemsavir). Individual results may vary. What is RUKOBIA?. RUKOBIA is a prescription medicine used with other human immunodeficiency virus-1...
Infectious H5N1 Influenza Virus in Raw Milk Rapidly Declines With Heat Treatment
The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research conducted by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. However, small, detectable amounts of infectious virus remained in raw milk samples...
Urged on by LGBTQ+ Activists, California Cities Weigh Stricter Smoking Rules
California has long been at the forefront of the fight against smoking, but some local officials in the San Francisco Bay Area, backed by activists who are especially concerned about high rates of smoking in the LGBTQ+ community, are spearheading proposals to further restrict how tobacco is sold and where it is smoked.
AIDS/LifeCycle 2024 Bike Ride Raises Nearly $11M for HIV Services
With seven days and 545 miles behind them, cyclists in the 2024 AIDS/LifeCycle ride raised $10,984,492 for HIV services. The annual event, which ended June 8, is coproduced by and supports the San Francisco AIDS Foundation (SFAF) and the Los Angeles LGBT Center. The first ride took place in 1994,...
Progress Against Anal Cancer Opens Door to Screening and Prevention
When Daniel G. Garza was diagnosed with anal cancer a decade ago, he had never heard of the disease. “Do you mean colorectal cancer?” he asked the doctor. The doctor explained that Garza had a tumor on his anal sphincter. At the time, Garza had been living with HIV for 14 years. But he did not know that gay and bisexual men, especially those with HIV, have an increased risk of anal cancer.
New Definition for Long COVID Could Aid in Consistent Diagnosis, Documentation and Treatment
A new National Academies of Sciences, Engineering, and Medicine report says the federal government, state and local authorities, clinicians, medical societies and organizations, public health practitioners, employers, educators, and others should adopt a new definition for “Long COVID” — that it is an infection-associated chronic condition that occurs after COVID-19 infection and is present for at least three months as a continuous, relapsing and remitting, or progressive disease state that affects one or more organ systems.
Experts Warn of Serious Health Impacts From Climate Change
Pregnant women, newborns, children, adolescents and older people are facing serious health complications due to climate change, according to a new collection of papers published in the Journal of Global Health, and yet the specific needs of these groups have been largely neglected in the climate response. The articles document...
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