[At the International AIDS Conference], HPTN 084 researchers presented new safety and pharmacokinetic (PK) findings for long-acting injectable cabotegravir (CAB-LA) [Apretude] when used before and during pregnancy. The findings show that CAB-LA used as pre-exposure prophylaxis (PrEP) was generally well tolerated and generally safe for both pregnant cisgender women and their babies. In addition, PK findings suggest that no dose changes are needed when using CAB-LA during pregnancy. To date, none of the women who became pregnant and continued to receive CAB acquired HIV during pregnancy.

Long-Acting Cabotegravir PrEP Is Safe During Pregnancy

Christian Azubike Enwuru1, Adenike Shola Aiyedobgon2, Morakinyo Bamikole Ajayi1 &. BMC Women's Health volume 24, Article number: 415 (2024) Cite this article. This study was undertaken to determine the prevalence of Bacterial Vaginosis (BV), Trichomonas Vaginalis (TV) co-infection, and the antibacterial sensitivity profile of bacterial isolates. Methods. The study was...

Bacterial vaginosis (BV) and Trichomonas vaginalis (TV) co-infection, and bacterial antibiogram profile of pregnant women studied in Lagos, Nigeria

A unique HIV cure case will be among the scientific highlights of AIDS 2024, the 25th International AIDS Conference, which will take place in Munich, Germany and virtually from 22 to 26 July. For the first time, scientists will share information about the “next Berlin Patient”, who appears to be...

First-of-its-kind HIV Cure Case Among Scientific Highlights at AIDS 2024

An overview of the complex relationships between herpes simplex virus, human papillomavirus, cytomegalovirus and HIV. Chronic viral infections from diseases such as between herpes simplex virus (HSV), human papillomavirus (HPV) and cytomegalovirus (CMV) can have a serious impact on those with immune systems already compromised by HIV, according to a session held today at the International AIDS Conference in Munich, Germany. The session featured three speakers who discussed each of these diseases.

Chronic Viral Infections Common in Those with HIV | AIDS 2024

Fetal station refers to the position your baby is in within your pelvis in late pregnancy and during labor. Your prenatal care provider might check your baby's station as your due date nears or during labor. Your baby's fetal station will change as you progress through the stages of labor....

What Pregnant People Should Know About Fetal Station

BabyCenter

A chemical pregnancy is a very early loss – so early that you may not know you were pregnant. Here's why it happens.

What is a chemical pregnancy?

Splenic vein thrombosis is a blockage in the splenic vein due to a blood clot. The splenic vein carries blood away from the spleen and parts of the stomach and pancreas. The spleen is an organ that filters and stores blood and produces white blood cells. A blood clot — also called a thrombus — in the splenic vein can cause blood to back up into the spleen, leading to various serious complications.

What to know about splenic vein thrombosis

Clackamas County, OR

ABC News

An Oregon hospital system is facing a lawsuit after more than 2,000 patients were possibly exposed to HIV and hepatitis.

Patients sue hospital system after thousands possibly exposed to HIV, hepatitis

Lenacapavir (Sunlenca), Gilead Sciences’ twice-yearly capsid inhibitor, demonstrated 100% efficacy for HIV prevention in a large study of young cisgender women in Africa. Oral PrEP is highly effective for people who can take it consistently, but additional options are still needed for people who have difficulty using daily pills. The Phase III PURPOSE 1 trial enrolled more than 5,300 women in South Africa and Uganda. They were randomly assigned to receive injectable lenacapavir once every six months or the daily PrEP pills Descovy (tenofovir alafenamide/emtricitabine) or Truvada (tenofovir disoproxil fumarate/emtricitabine) in a 2:2:1 ratio. There were zero new infections in the lenacapavir group, 39 in the Descovy group and 16 in the Truvada group. All three PrEP methods were well tolerated, and no new safety concerns were identified. A parallel study (PURPOSE 2) is testing lenacapavir PrEP for cisgender and transgender men, trans women and nonbinary people in the United States and six other countries; results are expected in late 2024 or early 2025.

Prevention: Twice-Yearly PrEP

Scripps News

We're closer to a cure for HIV than ever before. Scripps News examines the fight against a virus that has killed millions of people around the world in the last generation.

Scripps News Reports: The Cure for HIV

Cardiovascular complications are among the most common comorbidities affecting people with HIV (PWH), with studies showing increased risk for myocardial infarction, heart failure, and sudden cardiac death in these individuals despite treatment with antiretroviral therapy (ART).1 Compared with people without HIV, PWH have demonstrated up to twice the risk for cardiovascular disease,2 and this difference is not clearly linked to traditional risk factors or ART.1.

Reducing the Risk of CVD in Patients with HIV

On Tuesday at IAS’s AIDS 2024 in Munich, Germany, HIV.gov continued its daily coverage. Here are four updates:. Louis Shackelford of the HIV Vaccine Trials Network spoke with Dr. Carl Dieffenbach, Director of the Division of AIDS at National Institute of Health’s National Institute of Allergy and Infectious Diseases. They discussed the case report of the “Next Berlin patient,” a person living with HIV who is now in remission off of antiretroviral therapy following a stem cell transplant. Dr. Dieffenbach explained that this transplant was unique because both the donor and the recipient had a genetic makeup not previously seen in similar HIV cure case reports. They also discussed how this approach is only possible in unique circumstances when someone has a condition such as a cancer that requires a stem cell transplant, and discussed other approaches being explored for scalable HIV cure. Among them, he discussed the use of HIV broadly neutralizing antibodies—antibodies that bind to parts of HIV that remain relatively stable even when it mutates—in cure research. Finally, they discussed a new analysis from a large study of long-acting injectable cabotegravir (CAB-LA) for HIV pre-exposure prophylaxis (PrEP). Watch their conversation below and on YouTube:

Watch HIV.gov’s Day 2 at #AIDS2024: U=U University, NIH Updates & More

North Carolina State

Community Voices represent independent, third-party users who have joined our contributor program but not yet verified their accounts. Community Voices are expected, like all users, to adhere to our Community Standards.

community_voice

Town Talks

In North Carolina, the divorce process can be challenging, particularly due to the mandatory one-year separation requirement. This law mandates that couples must live separately for at least a year before filing for divorce, a rule that can be frustrating for many.

You might be granted a divorce in North Carolina if your spouse is ‘incurably insane.’ Here’s how

Ocilla, GA

Contributors represent independent, third-party users who have joined our contributor program and self-verified their accounts. They have also demonstrated their experience writing hard news for other outlets. Contributors are expected, like all users, to adhere to our Community Standards.

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Daily Coffee Press

Last Thursday, agents from the South Central Drug Task Force (SCDTF) made an arrest following a successful execution of a search warrant at a residence in Ocilla. According to officials, the search yielded a significant quantity of drugs, including tablets suspected to contain fentanyl, associated with a criminal street gang.

Successful Drug Bust in Ocilla Leads to Arrest Linked to 'Local Criminal Street Gang'

CBS News

Cancer cases among men are expected to surge globally in the coming years, with an estimated 93% increase in deaths by 2050, according to a new study. Dr. Jon LaPook explains.

Cancer cases and deaths expected to surge among men in coming decades

Secondary hypertension is when a person has high blood pressure due to another condition, such as kidney disease. Treating the underlying condition may reverse it. Genetic factors, diet, sedentary lifestyle, poor sleep, smoking, alcohol misuse, and obesity can cause primary hypertension. Secondary hypertension stems directly from another condition, such as...

What to know about secondary hypertension

The following is a summary of “Clinical manifestations and immune markers of non-HIV-related CMV retinitis,” published in the August 2024 issue of Infectious Disease by Passarin et al. Cytomegalovirus (CMV) retinitis primarily affected HIV-positive individuals with CD4+ cell counts below 50 cells/mm3 since the 1980s HIV epidemic. Researchers...

Clinical Manifestations and Immune Markers of Non-HIV-Related CMV Retinitis Identified

There is no single test to diagnose Sjögren disease. Doctors will carry out a range of tests, such as blood, eye, and salivary gland tests, to look for signs of the disorder and rule out other conditions. Sjögren disease is an autoimmune disorder that causes dry eyes and mouth....

How do doctors diagnose Sjögren disease?

Thanks to antiviral medications, HIV infection is no longer a death sentence. With a cocktail of drugs, people with HIV can keep the virus in check. Introduced more recently, PrEP, or pre-exposure prophylaxis, can guard uninfected people from potential infections. The pills, taken with a sip off water, have protected...

A Novel Treatment Slashes HIV Up To 10,000-Fold in Monkeys With Just a Single Dose

A single shot of an experimental injection dramatically reduces levels of the monkey form of HIV in nonhuman primates for at least 30 weeks, according to a study published today in Science. The new research suggests that the lab-made shot has the potential to offer a simple and durable alternative to the current standard treatment for people living with HIV, which is effective but demanding.

New HIV Treatment Approach Shows Promise in Monkeys

NewsBreak

HIV-Positive People Can Safely Breastfeed [VIDEOS]

+Life is a multi-platform brand inspired by journalist Karl Schmid’s personal story of living with shame and fear around his own HIV diagnosis. In his interview...

HIV-Positive People Can Safely Breastfeed [VIDEOS]

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