The Conversation UK

Scientists in America have developed a nasal spray that can remove proteins in the brain associated with Alzheimer’s disease – at least, in mice. There are two proteins implicated in Alzheimer’s: amyloid and tau. Most of the drugs – included those recently approved by the US Food and Drug Administration (FDA) – focus on removing amyloid. To date, though, there has been little focus on removing tau “tangles”. However, the new nasal spray, developed by researchers at the University of Texas Medical Branch, focuses on this protein.

Nasal spray clears proteins linked to Alzheimer’s – new study

Stanford, CA

Neuroscientists at Stanford have linked Alzheimer’s disease to the disruption of brain metabolism via the kynurenine pathway, which is affected by amyloid plaque and tau proteins. Their research has demonstrated that drugs blocking this pathway can restore cognitive function in Alzheimer’s mice by improving brain metabolism. This discovery not...

Stanford Reverses Cognitive Decline in Alzheimer’s With Brain Metabolism Drug

Researchers created an annotated library of gene readouts from 1.3 million brain cortex cells, focusing on individuals with and without Alzheimer’s disease. This comprehensive atlas, intended to enhance molecular understanding of cognitive resilience and vulnerability, reveals potential strategies for inducing cognitive resilience artificially. Less than a decade ago, when...

Unlocking Alzheimer’s Mysteries: Insights From Mapping 1.3 Million Brain Cells

A dopamine-based technique to tackle Alzheimer’s disease has been uncovered, potentially revolutionizing the way we diagnose, manage, and treat this debilitating condition. The innovative approach promises to change the landscape of Alzheimer’s treatment and offers new hope to millions affected by the disease. Unlocking the science. The esteemed...

Dopamine may help restore memory in Alzheimer’s patients

WEKU

Early in life, the protein Reelin helps assemble the brain. Later on, it appears to protect the organ from Alzheimer’s and other threats to memory and thinking.

A protein called Reelin keeps popping up in brains that resist aging and Alzheimer’s

A new study published in the journal Physiology & Behavior has found that adolescent rats modeled with autism-like symptoms showed significant improvements in brain function and cognitive abilities after regular treadmill exercise. These findings suggest that even low-intensity exercise could offer benefits for individuals with autism spectrum disorder, potentially enhancing cognitive flexibility through changes at the molecular level.

New autism research sheds light on how exercise boosts brain function

In the intricate architecture of​ the human ⁢brain, the emergence of Alzheimer’s disease often heralds a disheartening reality: a gradual and relentless‌ dismantling of memory,⁣ cognition, and identity. Yet, ⁣amidst ‌the shadows ‍cast by this formidable condition, ‍a new ray of ⁤hope has surfaced from the⁣ depths of‍ neuroscience research. ‌Recent studies are unveiling the intriguing relationship between dopamine—a neurotransmitter central to our ⁤feelings ‌of pleasure and reward—and the notorious brain plaques that characterize ‍Alzheimer’s. The idea​ that‍ this chemical messenger ‌could play a‍ pivotal role in dissolving harmful amyloid-beta plaques not only sparks ⁣curiosity but⁢ ignites a potential breakthrough in our understanding of neurodegenerative diseases. In this exploration, ​we delve⁢ into the science ‍behind dopamine’s unexpected therapeutic promise and the implications it holds for combating one ⁣of humanity’s most pressing health⁤ challenges. Join us as we unravel the layers of this complex puzzle, highlighting a⁣ path that may lead to a future where Alzheimer’s is no longer a looming specter but a challenge​ we can confidently confront.

Melting Away Alzheimer’s: How Dopamine Dissolves Harmful Brain Plaques

It's natural to experience some cognitive decline as we age, but not all cognitive deficits are a result of dementia. There are a variety of hormonal conditions and nutrient deficiencies that can present similar symptoms. If you’re having trouble concentrating or experiencing some memory loss, don’t panic just yet—rule out...

3 Conditions That Cause Cognitive Decline (But Aren't Dementia)

A collaborative study conducted by Duke-NUS and the NUS Mechanobiology Institute brings new hope for treating neurodevelopmental disorders by reactivating dormant neural stem cells and revealing additional mechanisms involved in brain development. Researchers at Duke-NUS Medical School and the Mechanobiology Institute at the National University of Singapore have identified a...

Breakthrough Discovery Awakens Dormant Brain Cells, Offering New Hope for Autism and Cerebral Palsy

Although the overall use of benzodiazepines does not appear to increase the risk of dementia, long-term use is associated with a reduction in the volume of critical brain areas, such as the hippocampus and the amygdala, according to new research published in BMC Medicine. This finding supports current medical guidelines that caution against prolonged benzodiazepine use.

Long-term benzodiazepine use linked to shrinkage in two brain regions

Everyday Health

Discover how neuroplasticity, the brain's ability to reorganize and form new connections, helps maintain cognitive health, recover from injury, and possibly delay cognitive decline.

Why Neuroplasticity Is Considered Your Brain's Superpower

The connection between migraines and cardiovascular health has been a topic of ongoing research for many years. While it is well-documented that migraines can be associated with an elevated risk of serious cardiovascular events like stroke, heart disease, and heart attack, the specific relationship between cardiovascular risk factors and the incidence of migraines remains less understood. A recent study published in Neurology explores this in depth.

Migraines and their link with cardiovascular health

shefinds

Supplements are often touted as a way to enhance overall health, but not all are created equal. While many supplements can offer benefits, some may inadvertently contribute to cognitive decline. Certain supplements, especially when taken in excess or without proper guidance, can interfere with brain function and mental clarity. It’s crucial to understand how specific supplements might affect cognitive health and to approach supplementation with informed choices.

7 Unexpected Supplements That May Actually Be Leading To Cognitive Decline, According To Experts: Folic Acid & More

Philadelphia, PA

Parade

Find out what dementia experts have to say about the connection.

A New Study Says This Commonly-Prescribed Medication Could Help Lower Dementia Risk By 50%

Maintaining brain health is essential for leading a long, vibrant life. As we age, the risk of cognitive decline and neurodegenerative diseases like Alzheimer’s increases, making it crucial to adopt preventive measures early on. The brain, bein...

Neuroscientist Says You Should Add These 3 Ingredients to Your Water for Better Brain Health—They Help Prevent Alzheimer's: Magnesium & More

A significant connection has been identified between severe menopause symptoms and cognitive impairment in postmenopausal women, according to findings from a study published in Menopause, the journal of The Menopause Society. A significant connection has been identified between severe menopause symptoms and cognitive impairment in postmenopausal women, according to findings...

Severe menopause symptoms linked to increased risk of cognitive decline in postmenopausal women

UPI News

Fish oil seen as possible way for high-risk seniors to avoid Alzheimer's

Saint Louis, MO

People with multiple sclerosis (MS) are far less likely than those without the condition to have the molecular hallmarks of Alzheimer’s disease, according to new research from Washington University School of Medicine in St. Louis. The discovery suggests a new avenue of research through which to seek Alzheimer’s treatments,...

Multiple sclerosis appears to protect against Alzheimer’s disease

A new experimental technique used to activate brain stem cells may be able to treat autism and cerebral palsy, creating new neural pathways that could help millions of children worldwide, if it is perfected. In a study published late last month in the journal Science Advances, a team of researchers...

Brain Cell Activation Technique May Help Treat Autism, Cerebral Palsy: Study

Alzheimer’s disease treatments aim to address symptoms such as memory loss, cognitive decline, difficulty with daily activities, and behavioral changes. While there is no current cure for Alzheimer’s disease, several medications can help manage symptoms and possibly slow its progression. Researchers are also exploring experimental treatments and off-label...

A Guide for Alzheimer’s Treatment Options

NewsBreak

Drugs that improve brain metabolism could help Alzheimer’s patients

Among the many ways neuroscientists think Alzheimer’s disease may strip away brain function is by disrupting the glucose metabolism needed to fuel the healthy brain. In...

Drugs that improve brain metabolism could help Alzheimer’s patients

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