Mountain View, CA

GT-02287, an oral small molecule from Gain Therapeutics, was found to be safe and well tolerated in healthy volunteers. It was also able to reach its target area, the brain, showing it has potential as a treatment for Parkinson’s disease linked to the GBA gene. The company plans to...

Gain readies for Phase 1b trial of Parkinson’s therapy GT-02287

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Total Apex Sports & Entertainment

September will be a month of healing for various zodiac signs. Uranus retrograde started on Sunday. It brings peace of mind and good luck to many people. Even so, the New Moon in Virgo on September 2 allows specific signs to organize things and end confusion. Have you found answers to all your questions?

3 Zodiac Signs With Intense Healing Energy | September 2, 2024

The FDA has granted fast track designation to [18F]PI-2620 for 3 neurodegenerative conditions, highlighting its potential to improve early diagnosis and treatment. According to a new announcement, the FDA has granted fast track designation to [18F]PI-2620, a tau positron emission tomography (PET) diagnostic, for several neurodegenerative diseases, including Alzheimer disease (AD), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD).1,2 This designation highlights the significant potential of [18F]PI-2620, developed in collaboration with AC Immune SA and Life Molecular Imaging, to improve diagnosis of these 3 neurodegenerative diseases.

FDA Grants Fast Track Designation to PI-2620 Tau-PET Diagnostic Scan for Neurodegenerative Diseases

Researchers at Yale have identified a protein that triggers loss of immune regulation associated with multiple sclerosis and other diseases. This discovery, which highlights the role of environmental factors like high salt intake, offers a new target for developing universal autoimmune treatments. Groundbreaking Discoveries in Autoimmune Research. More than two...

How Salt Triggers Multiple Sclerosis and Other Autoimmune Diseases: Yale’s Groundbreaking Discovery

Multiple sclerosis (MS) affects the brain and spinal cord limiting movement, vision, and others. Known as an autoimmune disorder, this chronic disease of the central nervous system slows or blocks signals between the brain and the rest of the body. The cause for this blocked signal is due to the deterioration of the myelin sheath around nerves, which helps move signals throughout the body. Symptoms include numbness, tingling, lack of coordination, difficulty walking, blurry vision, vertigo, slurred speech, cognitive problems, and others. Unfortunately, there is no cure for MS, but there are treatments to slow progression and manage symptoms. Scientists are still trying to understand the mechanism behind MS and develop treatments that will improve quality of life for patients.

Specialized Brain Cells Found to Drive Multiple Sclerosis

Stanford, CA

Neuroscientists at Stanford have linked Alzheimer’s disease to the disruption of brain metabolism via the kynurenine pathway, which is affected by amyloid plaque and tau proteins. Their research has demonstrated that drugs blocking this pathway can restore cognitive function in Alzheimer’s mice by improving brain metabolism. This discovery not...

Stanford Reverses Cognitive Decline in Alzheimer’s With Brain Metabolism Drug

Earth.com

A team of researchers from multiple universities, including the University of Virginia, has recently developed a system that identifies genetic markers of autism in brain images. The ingenious part? This system does so with an impressive accuracy between 89 and 95 percent.



The findings create ripples in the world of medicine. They signal a future where medical professionals can potentially identify, classify, and treat autism and related neurological conditions without waiting for behavioral cues. 



The implications of such a development are profound. The research could ultimately facilitate earlier interventions, drastically altering the experiences of those affected by autism.



Autism and genetics



"Autism is traditionally...

Scientists make history by cracking the Autism code

The company's vaccine consists of an mRNA sequence encoding a stabilized prefusion F glycoprotein. Coming off the heels of an FDA approval this past May, Moderna’s has received approval from the European Commission for its respiratory syncytial virus (RSV) vaccine, brand named mRESVIA. Hailing the approval, Moderna CEO Stéphane Bancel, stated that the approval was “an important milestone for public health and highlights Moderna’s mRNA leadership…marking the first time an mRNA vaccine has been approved for a disease beyond COVID-19 in Europe.”

Moderna's Vaccine Gets EU Approval for RSV

Scientists from the University of Sheffield have discovered a new sensory capability in bacteria which could transform treatments for bacterial infections. It was previously thought that bacteria are too small to directly sense differences in chemical concentration. However, contrary to decades of established scientific belief, a new study has shown bacteria can in fact directly sense their chemical environment across the length of their cell bodies with an unprecedented degree of precision.

New discovery of how bacteria navigate their environment could change how we treat infection

Researchers identify how brain circuits in mice amplify sensory prediction errors through a unique interaction between the neocortex and thalamus, shedding light on mechanisms that may contribute to ASDs and SSDs. Scientists at the Sainsbury Wellcome Centre at UCL have discovered how the neocortex and thalamus work together to detect...

Neural Surprises: Scientists Discover New Brain Mechanism

A new study has settled a prolonged dispute within the medical community by showing that mutations associated with clonal hematopoiesis heighten the risk of atherosclerosis in affected individuals. In addition to the established risk factors for cardiovascular disease—such as high blood pressure, high cholesterol, diabetes, obesity, smoking, and lack of...

Scientists Discover “Completely Different” New Risk Factor for Heart Disease

In August 2023, Gut, a journal published by BMJ, released a study of over 24,000 patients with Parkinson’s disease, finding that certain gastrointestinal disorders — such as difficulty swallowing, constipation, and irritable bowel syndrome (IBS) — might specifically predict Parkinson’s disease. The study aimed to methodically test Braak’s hypothesis, first postulated in 2003, which states that an unknown virus or bacteria in the gut could be a cause of Parkinson’s disease.

A Systems Approach To Parkinson's Disease

Being a health writer, I have a good grasp of how our immune system works. I’ve written about it often, including how to know if your immune system isn’t working properly, how to slow immune system aging and how inflammation can turn your immune system harmful. And when...

Boost your cancer-killing white blood cells in 30 minutes

What are some skywatching highlights in September 2024?. Five planets each make appearances, the Harvest supermoon shows us a partial eclipse, then slices through the Pleiades. Plus International Observe the Moon Night and solar sail sightings!. A Harvest Supermoon Eclipse. A partial lunar eclipse makes the full supermoon on September...

Don’t Miss September’s Stunning Supermoon Eclipse

Sepsis, a life-threatening syndrome induced by infection, has been a leading cause of hospitalization and death in U.S. healthcare settings and accounts for more hospital admissions and spending than any other condition.1,2 Early and effective diagnosis and treatment of sepsis, along with prevention, have been a patient-safety focus to improve outcomes and reduce mortality. Unfortunately, sepsis remains a significant challenge within the medical community due to its elusive nature and rapid progression.2 The heterogeneous presentation of sepsis often impedes efforts for early diagnosis and management.3.

Precision Medicine in Sepsis Diagnosis

Discoveries in the Arctic point to potential antivirulence antibiotics that could help overcome bacterial resistance. Antibiotics are vital to modern healthcare; without them, anyone with open wounds or undergoing surgery would face a constant risk of dangerous infections. Yet, the rapid evolution of new resistant strains of bacteria has significantly outpaced the discovery of fundamentally new antibiotics, leading to today’s global antibiotic resistance crisis.

Scientists Discover Promising Antibiotic Compounds Deep in the Arctic Sea

The Marijuana Herald

The Marijuana Herald - Marijuana news and information
A new study published in the journal BMJ Mental Health reveals promising insights into the effects of cannabidiol (CBD) on key biomarkers associated with schizophrenia. Conducted by researchers from Germany’s Central Institute of Mental Health, Goethe University Frankfurt, the University of Goettingen, and Australia’s University of Sydney, the randomized clinical trial explored how varying doses … 
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Study Finds THC Amplifies CBD’s Role in Improving Schizophrenia Symptoms

Researchers at Oak Ridge National Laboratory have uncovered groundbreaking chemistry in molten uranium trichloride, challenging conventional knowledge and paving the way for advancements in nuclear reactor design and waste management. The Department of Energy’s Oak Ridge National Laboratory is a world leader in molten salt reactor technology development — and...

Hotter Than Lava: The Surprising Science of Molten Uranium

Atomic clocks have been used for decades – but now, even greater precision has become possible: presenting the world’s first nuclear clock. Scientists have achieved a significant breakthrough by creating the world’s first nuclear clock using thorium atomic nuclei, enhancing the precision of time measurement. This innovative technology, though in its prototype phase, promises to surpass traditional atomic clocks in accuracy, potentially revolutionizing timekeeping and scientific measurements across various disciplines.

Precision Meets Power in the World’s First Thorium Nuclear Clock

A study reveals that higher PFAS levels during pregnancy correlate with greater weight and body fat at age 50, emphasizing the importance of reducing exposure to these harmful chemicals during pregnancy for long-term health benefits. Women with higher levels of per- and polyfluoroalkyl substances (PFAS) during pregnancy may experience long-term...

Exposure to Chemicals in Everyday Products During Pregnancy May Increase Risk of Obesity, Heart Disease Later in Life

NewsBreak

Crafting Tomorrow’s Cures: Unleashing Billions of Molecules To Accelerate Drug Discovery

Recent breakthroughs in DNA-encoded chemical libraries (DEL) have revolutionized the production of new molecular therapies, enabling the synthesis and testing of billions of substances rapidly. The...

Crafting Tomorrow’s Cures: Unleashing Billions of Molecules To Accelerate Drug Discovery

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