Dr Sekeres shares his thoughts about the choice between an EMA and a telomerase inhibitor in the RS-negative patient. With the advent of new options for treatment after ESAs for patients with LR-MDS, please share your thoughts about the choice between an EMA and a telomerase inhibitor in the RS-negative patient.

Second-line Treatment for RS-negative Lower-Risk MDS: Choosing Between EMA and Telomerase Inhibitor Options

Review of: Incidence of uveitis in patients with axial spondylarthritis treated with biologics or targeted synthetics: A systematic review and network meta-analysis. Bechman K, Yang Z, Adas M, et al. Arthritis and Rheumatology, May 2024. Treatment with certain immunomodulator therapies could help reduce the risk of anterior uveitis in patients...

Immunomodulators May Reduce Uveitis Risk in Patients With Axial Spondyloarthritis

Florida State

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Akeena

Red Lobster, the popular seafood chain, has confirmed additional closures in Florida, adding to its recent wave of shutdowns following the company’s bankruptcy filing in May. The latest round of closures includes two more Florida locations, highlighting the ongoing struggles of the iconic restaurant chain.

Popular seafood chain announces more closures in Florida

Orlando, FL

If you’ve been enjoying the vibrant food scene in Thornton Park, you might have heard some bittersweet news—Graffiti Junktion, the spot known for its top-notch burgers and laid-back vibe, has officially closed. After 16 years of serving up some of the best burgers in Orlando, the eatery has said its goodbyes. Here’s a closer look at why this cherished spot is shutting down and what it means for the community.

Favorite Florida Burger Place Closed Because Wages and Costs Went Up

Lake Mary, FL

If you're a fan of hearty breakfasts and brunches in Florida, you might have had Keke’s Cafe on your radar. Known for its generous portions and friendly service, Keke’s has been a go-to spot for many. However, the Lake Mary location recently hit a bump in the road, resulting in a temporary shutdown following a state inspection that uncovered 15 violations.

Breakfast Eatery Closed in Florida for Roaches, Dirty Hands, and Cold Foods Over 41 Degrees

North Carolina State

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Town Talks

A recent social media update from Cherokee, the site of North Carolina's first and only cannabis dispensary, announced that adult-use recreational marijuana is coming soon. The Aug. 1 post is a landmark occasion. The Great Smoky Cannabis Co., run by Qualla Enterprises backed by the Eastern Band of Cherokee, will become the first N.C. recreational marijuana dispensary to fully open to adults over the age of 21.

Will recreational marijuana be legal in NC? What to know after Cherokee approved sales

Interesting Engineering

Patients experienced a significant reduction in pain, improved their quality of life, and even showed signs of cartilage regrowth.

Stem cell shot reverses osteoarthritis, repairs knee cartilage, cuts pain by 58%

South Carolina State

Explore Beaufort SC

The mantis shrimp is one tough customer. Beautiful and deadly are two words you don’t typically use to describe shrimp, but the mantis shrimp is definitely in a class of its own; earning a reputation as the ‘savage boxer of the sea’ and one of the most fearsome creatures in the ocean. And, they're right at home here in South Carolina.

Savage Boxer of the Sea: The Deadly Beauty of Mantis Shrimp

Booneville, MS

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Mississippi News Group

A Booneville man finds himself in jail after children in his care tested positive for drugs according to a press release from the Booneville Police. After being indicted by the Prentiss County Grand Jury, 22 year old Dustin Blade Asher of Booneville has been charged with Two Counts of Child Endangerment. This charge relates to two children in his care testing positive for drugs, according to the Boonevile police.

Booneville Man Arrested For Child Endangerment After Children Test Positive For Drugs

Valrico, FL

Hey there, Floridians! If you're a fan of fresh produce and a farmer's market vibe, you might have some mixed feelings about the news from Valrico. The Fresh Market, known for its focus on organic options and quality meats and cheeses, is set to close its doors in the Lithia Crossings shopping center.

Grocery chain known for Organic options and quality meats is set to close its doors in Florida

Chicago, IL

Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Ohio State

The Lantern

On Tuesday, licensed Ohio dispensaries began legally selling non-medical marijuana to consumers; however, the drug’s possession, growth and/or usage are still prohibited on Ohio State’s campus. Credit: Jefferee Woo/Tampa Bay Times/TNS [Original caption: Four citizen-led petitions with proposals to update Dallas’ charter hit the 20,000 valid signature threshold to make it on the Nov. 5 election ballot, including one that would ban police officers from arresting or citing people carrying less than four ounces of marijuana.] As of Tuesday, students 21 and older can now legally purchase marijuana in Ohio.

Dispensary sales of recreational marijuana began Tuesday; possession and usage still prohibited on Ohio State’s campus

Study findings suggest the need for individualized management of patients with IgAN following COVID-19 infection based on baseline renal function status. Findings from a recent study are providing clinicians with an overview of the impact of mild to moderate COVID-19 infection on subsequent kidney function in patients with IgA nephropathy (IgAN).1.

Kidney Function in IgA Nephropathy Not Impacted by Mild, Moderate COVID-19 Infection

Ocilla, GA

Daily Coffee Press

Last Thursday, agents from the South Central Drug Task Force (SCDTF) made an arrest following a successful execution of a search warrant at a residence in Ocilla. According to officials, the search yielded a significant quantity of drugs, including tablets suspected to contain fentanyl, associated with a criminal street gang.

Successful Drug Bust in Ocilla Leads to Arrest Linked to 'Local Criminal Street Gang'

In part 1 of our interview with Anna Sureda, MD, PhD, president of the European Group for Blood and Marrow Transplantation, she summarized the current treatment landscape for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) and follicular lymphoma (FL). For our recent coverage of the European Hematology Association 2024 Congress,...

Advancements in R/R Lymphoma: Bispecific Antibodies in Focus

Tennessee State

John M. Dabbs

NASHVILLE, Tenn. — The Tennessee Department of Health (TDH) has issued a health alert to clinicians statewide following reports of severe acute illnesses and adverse effects of consuming Diamond Shruumz™ brand chocolate bars, cones, and gummies. The warning comes after the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) received reports of serious health issues linked to these mushroom-containing edible products.

Tennessee Health Alert: Severe Illnesses Linked to Diamond Shruumz™ Products

Patients with treatment-resistant depression who received repetitive transcranial magnetic stimulation (rTMS) experienced greater reduction and remission of symptoms than those who received another trial of an antidepressant, according to a report in AJP. “rTMS should be considered as a viable treatment option at an early stage of the treatment algorithm...

TMS More Effective Than Next-Step Antidepressant Treatment, Study Shows

Denver, CO

David Heitz

More dangerous substances are entering the Denver drug supply, Harm Reduction Action Center warned in a newsletter this week. “The Iron Law of Prohibition posits that as law enforcement becomes more intense, the potency of prohibited substances increases,” HRAC Executive Director Lisa Raville wrote in the newsletter. That is exactly what is happening, she said.

Dangerous substances entering Denver drug supply

Intranasal administration is a novel delivery method for the treatment of inflammatory human diseases. London-based Tiziana Life Sciences recently received fast track designation from the FDA for intranasal foralumab in the treatment of nonactive secondary progressive multiple sclerosis (SPMS). The company’s lead candidate is a fully human anti-CD3 monoclonal antibody currently in a phase 2a trial for the potential treatment of nonactive SPMS.

Intranasal Foralumab Receives Fast Track Designation for Nonactive Secondary Progressive MS

The drug showed a strong safety profile and met primary endpoints, showing efficacy in slowing clinical and biological decline and supporting further investigation in a phase 2/3 trial. In a new analysis of the phase 2 PIONEER trial (NCT04251182), treatment with investigational T3D-959 (T3D Therapeutics) resulted in statistically significant impacts...

Alzheimer Agent T3D-959 Demonstrates Disease-Modifying Effects in Phase 2 PIONEER Trial

NewsBreak

Patient Treatment Goals for Lower-Risk MDS

Dr Sekeres discusses treatment goals for...

Patient Treatment Goals for Lower-Risk MDS

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