Author(s): Robert Z. Orlowski, MD, PhD Jonathan L. Kaufman, MD. The panelists explore the evolution of treatment approaches for patients with relapsed/refractory multiple myeloma who have undergone 1-3 lines of therapy, with a particular focus on the implications of increased anti-CD38 monoclonal antibody usage in newly diagnosed or early relapse cases.

Expert Perspectives: Navigating the Evolving Treatment Landscape in Early Relapse MM

Belzutifan improved PFS and objective response compared with everolimus for patients with advanced renal cell carcinoma. Rates of treatment-related grade 3 or higher adverse events appeared similar in each group. Belzutifan significantly improved PFS and objective response compared with everolimus for patients with advanced renal cell carcinoma, according to results...

Belzutifan improves PFS, response in advanced renal cell carcinoma

Summary: Researchers have identified a natural molecule, phosphatidic acid, that reduces the sensitivity of touch-sensing ion channels, providing a promising new avenue for managing chronic pain. By increasing levels of this molecule, cells become less sensitive to touch, which was confirmed through tests on sensory neurons and in mice. This...

Molecule Discovery Could Revolutionize Chronic Pain Treatment

Alzheimer’s disease treatments aim to address symptoms such as memory loss, cognitive decline, difficulty with daily activities, and behavioral changes. While there is no current cure for Alzheimer’s disease, several medications can help manage symptoms and possibly slow its progression. Researchers are also exploring experimental treatments and off-label...

A Guide for Alzheimer’s Treatment Options

A meta-analysis demonstrated the superiority of Bruton tyrosine kinase inhibitors (BKTi) in the overall survival of patients with chronic lymphocytic leukemia compared with other therapies. Novel therapies demonstrated superior efficacy compared with immunotherapy and chemoimmunotherapy in patients with chronic lymphocytic leukemia (CLL) , according to a first-of-its-kind meta-analysis published in...

Novel Targeted Therapies Show Superiority in Relapsed/Refractory CLL

South Carolina State

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Explore Beaufort SC

The mantis shrimp is one tough customer. Beautiful and deadly are two words you don’t typically use to describe shrimp, but the mantis shrimp is definitely in a class of its own; earning a reputation as the ‘savage boxer of the sea’ and one of the most fearsome creatures in the ocean. And, they're right at home here in South Carolina.

Savage Boxer of the Sea: The Deadly Beauty of Mantis Shrimp

Everyday Health

Learn the differences between COPD and emphysema, as well as their symptoms, diagnosis methods, and treatments to improve breathing and quality of life.

Confused About COPD and Emphysema? Here's What You Need to Know

In August 2024, the FDA approved six new cancer treatments, including some that haven’t previously been approved. During the summer of 2024, the Food and Drug Administration (FDA) approved a handful of cancer treatments for patients with both solid and blood cancers. In August, the agency approved six more treatments, ranging from non-small cell lung cancer (NSCLC) to relapsed or refractory cutaneous T-cell lymphoma.

6 FDA Cancer Approvals from August 2024

Colorado State

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David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Health

Medically reviewed by Brigid Dwyer, MDMedically reviewed by Brigid Dwyer, MDThe sciatic nerve is the body’s largest and longest nerve, running from the lower back down through the back of each leg. This nerve stimulates leg muscle movement and carries sensory signals from the legs to the spine, helping you complete daily functions like walking and standing. Irritation of or damage to the sciatic nerve can lead to multiple health conditions, causing pain, numbness, tingling, and more.Anatomy of the Sciatic NerveThe sciatic nerve is a part of your peripheral nervous system, which is made up of the nerves that exist...

A Complete Guide to Your Sciatic Nerve

Early palliative care improved quality-of-life indicators including coping skills, self-management, and 2-year survival rate in adults with advanced cancer. Early palliative care improved scores in overall health status or quality of life (QOL) at 18 weeks in patients with advanced cancer, according to findings published in JAMA Network Open. In...

Early Palliative Care May Improve Quality of Life in Advanced Cancer

Massachusetts State

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Dianna Carney

Sandy Paws Rescue Inc., a foster-based rescue in Massachusetts, has recently introduced a tiny 8lb dog named Bingo who is looking for her forever home. Bingo is a 3-year-old Shih Tzu mix with an adorable appearance and a sweet disposition. However, she needs a patient and understanding owner who recognizes that "dogs are not toys, and not all dogs love to be picked up right away," explains Sandy Paws Rescue Inc. This little lady requires some decompression time upon arriving at her new home to settle in comfortably.

Meet The Sweet Little Lady Looking For Love

A panel of medical experts explore how to evaluate and adjust rheumatoid arthritis treatment by adhering to ACR guidelines for conventional synthetic DMARDs and advanced therapies, focusing on optimizing patient care and treatment outcomes. Video content above is prompted by the following:. Conventional synthetic disease-modifying antirheumatic drugs (csDMARDS), including methotrexate,...

Evaluating and Adjusting Rheumatoid Arthritis Treatment: Adhering to ACR Guidelines for csDMARDs and Advanced Therapies

Florida State

Jacksonville, FL

Jacksonville Today

Jacksonville Sheriff T.K. Waters said he will consider more DUI patrols if voters legalize recreational marijuana use in Florida. Voters will consider Amendment 3 in November. It would allow adults 21 or older to possess, purchase or use marijuana products and marijuana accessories for non-medical purposes.

More DUI patrols possible if marijuana issue passes

Ohio State

The Lantern

On Tuesday, licensed Ohio dispensaries began legally selling non-medical marijuana to consumers; however, the drug’s possession, growth and/or usage are still prohibited on Ohio State’s campus. Credit: Jefferee Woo/Tampa Bay Times/TNS [Original caption: Four citizen-led petitions with proposals to update Dallas’ charter hit the 20,000 valid signature threshold to make it on the Nov. 5 election ballot, including one that would ban police officers from arresting or citing people carrying less than four ounces of marijuana.] As of Tuesday, students 21 and older can now legally purchase marijuana in Ohio.

Dispensary sales of recreational marijuana began Tuesday; possession and usage still prohibited on Ohio State’s campus

PET scans that determine whether men with prostate cancer are eligible for Pluvicto treatment can provide additional clues on how they may respond to the drug, according to a study published August 20 in Radiology. In an analysis of clinical trial data, researchers found that uptake by tumors of the...

PET scans predict patient response to Pluvicto

Acute clinical events with stable MRI were more likely among patients with multiple sclerosis who had longer disease duration, received highly effective disease-modifying therapies, and who presented with fatigue. This article was originally published on NeurologyLive®. In a new multicenter observational cohort study published in JAMA Neurology, approximately one-fourth...

Stable MRI in Multiple Sclerosis Reveals Relapses as Acute Clinical Events

Dr. Faith A. Richardson

Multiple Sclerosis is a progressive disease such as demyelinating and affects the motor and sensory neurons. The disease will cause cycles of remission, which causes the condition to worsen. When exacerbation starts etiology is reviewed, which includes the cause? The cause at this time is not clear, yet some experts believe that viral infections and autoimmune disease plays a part in Multiple Sclerosis cause.

Associating Back Pain and Multiple Sclerosis

Los Angeles, CA

Herbie J Pilato

It's been four decades since Emmy-nominated actor Lloyd Haynes died of lung cancer at only 52 years old. Best known for his compassionate performance as history teacher Pete Dixon on television's groundbreaking, academic-geared dramedy, Room 222 (ABC, 1969-1974), Haynes was beloved by his fans, family, friends and colleagues alike. This is his story.

In Memory of 'Room 222' TV Actor Lloyd Haynes: 4 Decades After His Tragic Death From Lung Cancer

Diabetic retinopathy (DR) usually takes several years to develop. In many cases, it may take at least 5 years for the condition to develop after a diagnosis of diabetes. However, the onset, progression, and extent of vision loss can vary widely. The risk of DR can. the longer a person...

How quickly can diabetic retinopathy develop?

NewsBreak

Navigating Treatment Options for HER2+ BC: A Need for Customization

Adrienne Waks, MD, discusses the unmet needs in early-stage HER2-positive breast cancer. The DAPHNe trial (NCT03716180) investigated the prevalence and dynamics of circulating tumor DNA (ctDNA)...

Navigating Treatment Options for HER2+ BC: A Need for Customization

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