The phase 3 inMIND trial evaluating tafasitamab in combination with lenalidomide and rituximab in relapsed or refractory follicular lymphoma showed promising progression-free survival findings, according to topline results. This article was originally published by Targeted Oncology®. The pivotal phase 3 inMIND trial (NCT04680052) of tafasitamab-cxix (Monjuvi), a humanized Fc-modified...

Phase 3 Trial of Tafasitamab in Follicular Lymphoma Meets Primary End Point

Reuters

GDANSK (Reuters) - BioNTech on Monday said the U.S. Food and Drug Administration (FDA) has lifted a partial clinical hold on an early stage study of its experimental cancer drug.

BioNTech says FDA lifts partial hold on its cancer drug trial

The FDA has approved first-line amivantamab plus lazertinib for locally advanced or metastatic EGFR-mutated non–small cell lung cancer. The FDA has approved amivantamab-vmjw (Rybrevant) in combination with lazertinib (Lazcluze) for the first-line treatment of adult patients with locally advanced or metastatic non–small cell lung cancer (NSCLC) harboring EGFR exon 19 deletions or exon 21 L858R substitution mutations, as detected by an FDA-approved test.1.

FDA Approves First-Line Amivantamab Plus Lazertinib for EGFR+ Advanced NSCLC

Approval is based off results from the Phase III MARIPOSA study, which showed Rybrevant in cominbation with Lazcluze reduced the risk of disease progression or death by 30% versus osimertinib. The FDA has approved Johnson & Johnson’s Rybrevant (amivantamab-vmjw) plus Lazcluze (lazertinib) for the treatment of adult patients with locally...

FDA Approves Rybrevant Combination for Advanced Non-Small Cell Lung Cancer

Ohio State

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The Lantern

On Tuesday, licensed Ohio dispensaries began legally selling non-medical marijuana to consumers; however, the drug’s possession, growth and/or usage are still prohibited on Ohio State’s campus. Credit: Jefferee Woo/Tampa Bay Times/TNS [Original caption: Four citizen-led petitions with proposals to update Dallas’ charter hit the 20,000 valid signature threshold to make it on the Nov. 5 election ballot, including one that would ban police officers from arresting or citing people carrying less than four ounces of marijuana.] As of Tuesday, students 21 and older can now legally purchase marijuana in Ohio.

Dispensary sales of recreational marijuana began Tuesday; possession and usage still prohibited on Ohio State’s campus

Georgia State

Atlanta, GA

Daily Coffee Press

A 40-year-old man has been sentenced to over 28 years in prison for distributing significant amounts of fentanyl and other controlled substances to dealers in the Middle Georgia region. Authorities revealed that investigators uncovered evidence linking the drugs provided by the defendant, 40-year-old Lagary Williams, also known as "Frog," from Atlanta, to a fatal overdose.

Atlanta Man Sentenced to 28 Years for Supplying Deadly Fentanyl Linked to Fatal Overdose

Colorado State

David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Jacksonville, FL

Jacksonville Today

A historic marker could be erected to honor the victims of the racist mass shooting at the Dollar General store in Jacksonville’s New Town neighborhood nearly a year ago. If approved by the Jacksonville City Council, a marker would be installed at Kings Road and Canal Street on Aug. 25, a day before the first anniversary of the shooting, when a white gunman took the lives of three Black people.

Memorial considered to honor Dollar General victims

Mild-to-moderate IPF may cause adaptive changes in feeding that are closely linked to nutritional status, lung function, and the severity of dyspnea. Swallowing is an intricate process that necessitates the coordinated activity of muscles in the mouth, pharynx, larynx, and esophagus, explained a study published online in BMC Pulmonary Medicine. Dysphagia, a condition marked by difficulty swallowing, can significantly exacerbate respiratory diseases by potentially increasing lung disease exacerbations and hastening the decline in pulmonary function. This study sought to examine swallowing dynamics in patients with idiopathic pulmonary fibrosis (IPF) and its association with tongue pressure, pulmonary function, and overall health status.

Addressing the Knowledge Gap: Idiopathic Pulmonary Fibrosis and Swallowing

Acute Monoblastic Leukemia is a rare but aggressive type of cancer affecting the blood and bone marrow. It primarily involves monoblasts, which are immature white blood cells. This disease progresses rapidly, requiring prompt diagnosis and treatment. Symptoms often include fatigue, fever, and frequent infections. Risk factors can range from genetic predispositions to previous chemotherapy treatments. Understanding this condition is crucial for early intervention and better outcomes. In this post, we'll explore 20 essential facts about Acute Monoblastic Leukemia, shedding light on its causes, symptoms, treatments, and more. Stay informed to better recognize and combat this challenging disease.

20 Facts About Acute Monoblastic Leukemia

In August 2024, the FDA approved six new cancer treatments, including some that haven’t previously been approved. During the summer of 2024, the Food and Drug Administration (FDA) approved a handful of cancer treatments for patients with both solid and blood cancers. In August, the agency approved six more treatments, ranging from non-small cell lung cancer (NSCLC) to relapsed or refractory cutaneous T-cell lymphoma.

6 FDA Cancer Approvals from August 2024

Denver, CO

In addition to collecting more than 8,000 used needles in the past year from Denver drug users, the Harm Reduction Action Center passed out 10,000 meth pipes and “snort kits,” according to a newsletter sent to its supporters Thursday. They also connected about 1,700 people to medical, mental health and substance abuse treatment.

Denver group hands out 10K meth pipes, ‘snort kits,’ connects 1,700 to treatment annually

Researchers have demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy may improve progression-free survival in patients with oligometastatic pancreatic cancer, according to a recent study published by Ludmir et al in the Journal of Clinical Oncology and previously presented at the 2024 ASCO Gastrointestinal Cancers Symposium (Abstract 603). Background.

Metastasis-Directed Radiation Therapy Plus Chemotherapy in Oligometastatic Pancreatic Cancer

Virginia State

Community Voices represent independent, third-party users who have joined our contributor program but not yet verified their accounts. Community Voices are expected, like all users, to adhere to our Community Standards.

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Kentucky Vibes.net

Disclaimer: This article was written with the help of A.I. software. On July 28, 2024, a TikTok video posted by Erica W., known as @tasteofmelanin on the platform, garnered significant attention after she exposed disturbing racist decorations in an Airbnb rental. The incident occurred in a rental property that Erica had booked, although the exact location remains unspecified. The video has since gone viral, prompting widespread concern and leading to the removal of the listing from Airbnb's platform.

Airbnb Listing Taken Down After Black Woman Finds Hanging Monkeys and Cotton Used As Decor

Breyanzi demonstrated an overall high response rate in adults with relapsed or refractory follicular lymphoma in a Phase II study. The European Medicines Agency (EMA) has validated a Type II variation application that expands the indication for Breyanzi, a Bristol Myers Squibb product, to include treatment of adults with relapsed or refractory follicular lymphoma (FL) who have received two or more prior lines of systemic therapy (1). The validation, which confirms the completion of the therapy’s submission to EMA and allows scientific review to begin, was announced by Bristol Myers Squibb in a press release on Aug. 19, 2024.

Bristol Myers Squibb Follicular Lymphoma Therapy Gets Expanded EMA Indication

Healthline

R-ICE is a treatment for non-Hodgkin's and Hodgkin's lymphoma. It combines four chemotherapy drugs that kill cancer cells and is often used prior to a stem cell transplant. Learn more.

What Is the R-ICE Chemotherapy Protocol?

South Carolina State

Explore Beaufort SC

The mantis shrimp is one tough customer. Beautiful and deadly are two words you don’t typically use to describe shrimp, but the mantis shrimp is definitely in a class of its own; earning a reputation as the ‘savage boxer of the sea’ and one of the most fearsome creatures in the ocean. And, they're right at home here in South Carolina.

Savage Boxer of the Sea: The Deadly Beauty of Mantis Shrimp

SurvivorNet

Non smoker diagnosed Wirth lung cancer and EGFR medications used

Dismissed By Doctors, Distance Runner Mom, 43, Diagnosed With Lung Cancer– She Never Smoked

The Lens

This year’s area of low oxygen in the Gulf of Mexico is larger than average, the National Oceanic and Atmospheric Administration (NOAA) announced on Thursday. The “dead zone” is approximately 6,705 square miles , as measured last week. Within NOAA’s 38 years of measuring the dead zone, this year’s assessment marks the 12th-largest area of low to no oxygen, which can kill fish and marine life.

Gulf ‘dead zone’ larger than average, larger than expected for 2024, scientists announce

Small cell lung cancer (SCLC) is a fast-growing cancer that develops in cells within the lung. A range of medical tests and procedures are available to help doctors diagnose SCLC and create an appropriate treatment plan. Lung cancer is a complex disease comprising various subtypes. A person who receives a...

How do doctors diagnose small cell lung cancer?

NewsBreak

Phase 2 Trial of Nab-Sirolimus in Solid Tumors Stops Due to Futility

An independent data monitoring committee assessed that the PRECISION1 trial of nab-sirolimus in solid tumors would not meet an efficacy threshold to support the agent’s accelerated...

Phase 2 Trial of Nab-Sirolimus in Solid Tumors Stops Due to Futility

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