Opening lines: Toledo a 9.5-point underdog at Mississippi State

For the first time this season, the University of Toledo enters a football game as the betting underdog.

In early lines released by online sportsbooks, Toledo is a 9.5-point underdog for Saturday’s 7:30 p.m. contest at Southeastern Conference opponent Mississippi State. A Rockets victory earns a bettor $295 on a $100 bet, while those who want to bet Mississippi State to win need to put down $375 to win $100. The over/under is 57.5 points.

Michigan, which fell to 17th in the Associated Press Top 25 following its loss Saturday to Texas, is favored by 23.5-24 points over Arkansas State.

Notre Dame, now 18th after losing to Northern Illinois on Saturday, is favored by 11.5-12.5 points at Purdue.

Here’s a deeper look at the betting lines at a sampling of online sportsbooks. Bowling Green and Ohio State are both off this week.

Toledo (2-0) at Mississippi State (1-1), 7:30 p.m., ESPNU

DraftKings: Mississippi State favored by 9.5, Total 57.5. Toledo money line +295. Mississippi State money line -375.

ESPN Bet: Mississippi State favored by 9.5, Total 57.5. Money line not set.

FanDuel: Mississippi State favored by 9.5, Total 57.5. Toledo money line +245. Mississippi State money line -310.

Arkansas State (2-0) at No. 17 Michigan (1-1), noon, BTN

DraftKings: Michigan favored by 24. Total 45.5. Arkansas State money line +1300. Michigan money line -2800.

ESPN Bet: Michigan favored by 24. Total 45.5. Money line not set.

FanDuel: Michigan favored by 23.5. Total 45.5. Arkansas State money line +1400. Michigan money line -4000.

No. 18 Notre Dame (1-1) at Purdue (1-0), 3:30 p.m., CBS

DraftKings: Notre Dame favored by 12. Total 45.5. Notre Dame money line -500. Purdue money line +380.

ESPN Bet: Notre Dame favored by 12.5. Total 45.5. Money line not set.

FanDuel: Notre Dame favored by 11.5. Total 45.5. Notre Dame money line -530. Purdue money line +390.