Get updates delivered to you daily. Free and customizable.
The Conversation U.S.
Racism and discrimination lead to faster aging through brain network changes, new study finds
By Negar Fani, Emory University and Nathaniel Harnett, Harvard University,
10 days ago
Racism steals time from people’s lives – possibly because of the space it occupies in the mind. In a new study published in the journal JAMA Network Open, our team showed that the toll of racism on the brain was linked to advanced aging , observed on a cellular level.
Black women who were more frequently exposed to racism showed stronger connections in brain networks involved with rumination and vigilance. We found that this, in turn, was connected to accelerated biological aging.
Racial discrimination is a ubiquitous stressor that often goes unnoticed. It might look like a doctor questioning a Black patient’s pain level and not prescribing pain medication, or a teacher calling a Black child a “thug.” It is a constant stressor faced by Black people starting at an early age.
Rumination – reliving and analyzing an event on a loop – and vigilance , meaning being watchful for future threats, are possible coping responses to these stressors. But rumination and vigilance take energy, and this increased energy expenditure has a biological cost.
In our study of Black women, we found that more frequent racial discrimination was linked to more connectivity between two key regions. One, called the locus coeruleus , is a deep brain region that activates the stress response, promoting arousal and vigilance. The other is the precuneus , a key node of a brain network that engages when we think about our experiences and internalize – or suppress – our emotions.
These brain changes, in turn, were linked to accelerated cellular aging measured by an epigenetic “clock.” Epigenetics refers to changes that happen to our DNA from the environment. Epigenetic clocks assess how the environment affects our aging at a molecular level.
Higher clock values indicate that someone’s biological age is greater than their chronological age. In other words, the space that racist experiences occupy in people’s minds has a cost, which can shorten the lifespan.
What still isn’t known
Although we saw links between racism, brain connectivity changes and accelerated aging, we did not measure coping responses like rumination and vigilance in real time, meaning as people were experiencing them.
Our next steps are to use real-time measurement of everyday racism along with physiological measurements and neuroimaging to take a deeper dive into these research questions.
We want to know how different types of racial discrimination and coping styles influence brain and body responses. Understanding these issues better can bring more attention to prevention, such as programs that target implicit bias in physicians and teachers. It can also inform interventions like neuromodulation , which involves the use of external or internal devices to stimulate or inhibit brain activity. Neuromodulation can be used as a therapy aid to reduce stress.
The Research Brief is a short take on interesting academic work.
Negar Fani receives funding from the National Institutes of Health and Emory University School of Medicine.
Nathaniel Harnett is an Assistant Professor at McLean Hospital/Harvard Medical School. He receives funding from the National Institutes of Health, McLean Hospital, and Harvard Catalyst.
Get updates delivered to you daily. Free and customizable.
It’s essential to note our commitment to transparency:
Our Terms of Use acknowledge that our services may not always be error-free, and our Community Standards emphasize our discretion in enforcing policies. As a platform hosting over 100,000 pieces of content published daily, we cannot pre-vet content, but we strive to foster a dynamic environment for free expression and robust discourse through safety guardrails of human and AI moderation.
Comments / 0