The 2024-25 NFL season has begun which means fantasy football is back! The fantasy landscape has already changed since the preseason due to breakout players and major injuries across the league. This makes it the appropriate time of year to begin deferring from some of the players originally drafted to be starters and play some of the players that have overperformed this season as opposed to performing at their preseason expectation. Since every week is important it would be irresponsible to start a player with a rough matchup over a player with a more favorable one that is ranked or projected to perform similarly. Here are fantasy football Week 4 running back rankings.