Watch: Jesse Eisenberg, Kieran Culkin tour Poland in 'A Real Pain'

Sept. 25 (UPI) -- Searchlight Pictures released a preview of Jesse Eisenberg 's A Real Pain on Wednesday.

Eisenberg portrays straight-laced David, who tours Poland with his wild cousin Benji, portrayed by Kieran Culkin .

"Our grandma was from here, so Dave arranged for us to join this geriatric Polish tour with you fine people," Benji says in the trailer . "...I've just been in a real funk, I guess, since she died."

Despite the heavy subject matter, the movie also promises comedic moments , such as when the duo miss their exit because Benji doesn't want to wake a peacefully-sleeping David.

"The adventure takes a turn when the odd-couple's old tensions resurface against the backdrop of their family history," an official description reads.

In addition to Eisenberg and Culkin, the film also stars Will Sharpe, Jennifer Grey , Kurt Egyiawan, Liza Sadovy and Daniel Oreskes.

The film, directed by Eisenberg, premieres in theaters in fall.