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    San Francisco 49ers at Minnesota Vikings: Predictions, picks and odds for NFL Week 2 game

    By Jordan Mendoza, USA TODAY,

    8 hours ago

    Who will move on to 2-0 when the San Francisco 49ers (1-0) and Minnesota Vikings (1-0) square off?

    Christian McCaffrey didn't play, but the 49ers didn't skip a beat when they crushed the New York Jets on "Monday Night Football." Backup Jordan Mason had the best game of his young career and San Francisco looked every bit of a team looking to change its Super Bowl misfortune into a title victory.

    Perhaps the most surprising performance in Week 1 was Sam Darnold, who looked like a prime quarterback leading the Vikings to a win over the New York Giants. There were questions if the offense could do enough this season, but if Minnesota plays like how it did in Week 1, it could be a sneaky playoff team.

    PROP TALK: These are the best prop bets for NFL games this week

    Vikings vs. 49ers odds, moneyline, over/under

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    • Spread: 49ers (-6)
    • Moneyline: 49ers (-275); Vikings (+220)
    • Over/under: 45.5

    Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered with Thursday Night Football odds and Monday Night Football odds .

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    FEELING LUCKY? Here are the best parlay bets and odds for NFL games this week

    https://img.particlenews.com/image.php?url=296hl8_0vSWirMT00
    The line of scrimmage between the Minnesota Vikings and the San Francisco 49ers during the game at U.S. Bank Stadium. Jeffrey Becker-USA TODAY Sports

    NFL Week 2 odds, predictions and picks

    Dolphins vs. Bills | Ravens vs. Raiders | Panthers vs. Chargers | Cowboys vs. Saints | Lions vs. Buccaneers | Packers vs. Colts | Jaguars vs. Browns | Vikings vs. 49ers | Patriots vs. Seahawks | Titans vs. Jets | Commanders vs. Giants | Cardinals vs. Rams | Chiefs vs. Bengals | Broncos vs. Steelers | Texans vs. Bears | Eagles vs. Falcons

    Lorenzo Reyes: 49ers 33, Vikings 12

    I don’t see Sam Darnold — even with his solid game against the Giants — keeping pace with the 49ers offense. Regardless of whether Christian McCaffrey plays, San Francisco could get whatever yards it wanted against the Jets, a far better defense than Minnesota’s.

    Tyler Dragon: 49ers 30, Vikings 20

    The 49ers looked like they were ready to make a return trip to the Super Bowl after an early Week 1 statement. WR Justin Jefferson is going to be a matchup problem for San Francisco’s secondary, but that’s Minnesota’s only advantage. The 49ers are still the top team in the NFC.

    Richard Morin: 49ers 27, Vikings 21

    The spread is a bit risky here, but I could see the Vikings finding a rhythm on offense in this one. The 49ers will win, but the over might be the play.

    Jordan Mendoza: 49ers 24, Vikings 20

    After Monday's performance without Christian McCaffrey, it's tough seeing anyone able to take down the reigning NFC champions. Last season, Minnesota surprised San Francisco at home. While this game should be close, the 49ers shouldn't falter this time around. The defense holds on to move to 2-0.

    MOST VALUABLE BET: Who is the favorite to win NFL MVP in 2024?

    This article originally appeared on USA TODAY: San Francisco 49ers at Minnesota Vikings: Predictions, picks and odds for NFL Week 2 game

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    Comments / 2
    Add a Comment
    William Schmitz
    5h ago
    fake football
    JustMe
    7h ago
    They’re giving the Vikings 6 points, wow. That’s a great bet to take. No Mccaffrey either. It’s the Vikings home opener and darnold will outplay purdy.
    View all comments
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