Indianapolis Colts at Green Bay Packers: Predictions, picks and odds for NFL Week 2 game

Narrow defeats for the Green Bay Packers (0-1) and the Indianapolis Colts (0-1) spoiled their season openers, but they'll get the chance to turn the page against each other in Week 2.

Anthony Richardson came back under center for Indianapolis after an injury ended his rookie season early. However, the new additions for the Houston Texans proved why they're one of the emerging teams in the AFC, taking down their divisional foe at Lucas Oil Stadium.

Green Bay played in the first NFL Brazil game, and not only did it lose to the Philadelphia Eagles , but it likely lost Jordan Love for some time due to a late injury. With the franchise quarterback expected to miss time, Malik Willis will take his place and attempt to get the ball rolling for a team that had tremendous momentum from last season.

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Packers vs. Colts odds, moneyline, over/under

The Colts are favorites to defeat the Packers, according to the BetMGM NFL odds . Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code .

• Spread: Colts (-3.5)
• Moneyline: Colts (-175); Packers (+145)
• Over/under: 41

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Lorenzo Reyes: Colts 27, Packers 16

I just don’t know that you can back a team led by Malik Willis, given the absence of Jordan Love. I am very high on both these teams, but Green Bay is at a severe disadvantage with its backup starting. I also think Indy will feel added pressure to not fall into an 0-2 hole after a close loss against the AFC South-rival Texans.

Tyler Dragon: Colts 24, Packers 17

I would’ve picked the Packers in this game before the year. But Green Bay’s season took a turn for the worse once Jordan Love went down in the final seconds of the team’s Week 1 loss. Malik Willis has a chance to revitalize his career in the next few weeks while Love is out. However, Anthony Richardson and the Colts will get their first victory of the season Sunday.

Richard Morin: Packers 16, Colts 13

The Packers are for real, even if they have to get creative without Jordan Love for a while. The under is the only safe play here.

Jordan Mendoza: Colts 22, Packers 20

With Jordan Love likely not playing, it's anyone's guess as to how Malik Willis plays for a team that just traded for him a few weeks ago. Running back Josh Jacobs should help carry the load, but the Colts offense is better than people think. Anthony Richardson has his first signature drive to push Indianapolis to victory.

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This article originally appeared on USA TODAY: Indianapolis Colts at Green Bay Packers: Predictions, picks and odds for NFL Week 2 game