Notre Dame vs. Louisville: Predictions, odds, how to watch Saturday's game

The Notre Dame Fighting Irish will host the Louisville Cardinals in nonconference Week 5 matchup.

The Fighting Irish (3-1) are ranked No. 14 in the US LMB Coaches Poll this week after a 28-3 victory over Miami of Ohio. The Cardinals (3-0) are ranked No. 17 after a 31-19 victory over Georiga Tech last week.

Louisville quarterback Tyler Shough completed 13 of 19 passes for 269 yards and two touchdowns in the victory. The Cardinals didn't produce much on the ground, with Donald Chaney Jr. serving as the leading rusher with 23 yards on 10 carries.

Notre Dame quarterback Riley Leonard completed 16 of 25 passes for 154 yards and a touchdown against the Redhawks. He also contributed on the ground with 143 yards and two touchdowns on12 carries last week.

Here's what to know about the Notre Dame-Louisville Week 5 matchup on Saturday:

College football 2024: Notre Dame vs. Louisville predictions

College Football News : Notre Dame 26, Louisville 17

Pete Fiutak writes "This is the game Notre Dame appears to have circled. It appears to be one of those teams that needs that type of challenge-us-please thing happening. Be sort of stunned if this isn’t the most physical the Irish have been all year, especially on the defensive front."

Sports Illustrated : Notre Dame 24, Louisville 21

James Parks writes "Shough will find some creases on the back end of this defense that will make things tense for the home crowd, but the Irish have the bodies to contest the Louisville offense in scoring position and hold it to field goals instead of touchdowns."

Sports Book Wire: Notre Dame 21, Louisville 17

Ryan Dodson writes "Because of potentially soggy conditions, Notre Dame has a big-time advantage being at home with a better running game."'

SCHEDULE: Keep up with all the scores and stats for Week 5 games

Notre Dame vs. Louisville odds, lines:

Notre Dame is the favorite to defeat Louisville in Saturday's college football matchup, according to the BetMGM college football odds .

Odds as of Friday.

• Spread : Notre Dame (-7)
• Moneylines : Notre Dame (-275); Louisville (+220)
• Over/under : 45.5

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How to watch Notre Dame vs. Louisville:

• Date: Saturday, Sept. 28
• Where: Notre Dame Stadium (Notre Dame, Indiana)
• Time: 3:30 p.m. ET
• Stream: Peacock

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This article originally appeared on USA TODAY: Notre Dame vs. Louisville: Predictions, odds, how to watch Saturday's game