SportsbookWire's NFL Week 2 picks: ML, ATS and O/U predictions for all games

Week 2 kicks off with an AFC East showdown in South Florida Thursday night as the Miami Dolphins host the Buffalo Bills in a meeting of 1-0 rivals.

There are 5 more matchups involving 1-0 teams facing off Sunday.

They include the Dallas Cowboys hosting the New Orleans Saints, the Detroit Lions welcoming the Tampa Bay Buccaneers, the San Francisco 49ers at the Minnesota Vikings, the Seattle Seahawks at the New England Patriots and the Chicago Bears at the Houston Texans in the prime-time game.

The week concludes with the Atlanta Falcons (0-1) at the Philadelphia Eagles (1-0) on Monday Night Football at 8:20 p.m. ET (ABC / ESPN).

Before getting to SportsbookWire.com staff’s Week 2 NFL picks, here’s a quick rundown of Week 1.

Favorites went 13-3 straight up and 9-7 against the spread, while the Over was 9-7.

NFL Week 2 staff picks

Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds and check out more NFL expert picks and predictions from SportsbookWire.com.

WIN YOUR FANTASY FOOTBALL LEAGUE!

The Huddle has been turning players like you into winners for over 25 years. This season, it’s your turn. Custom fantasy football rankings, sleepers and tools are just a click away. Save 25% off the Internet’s best-kept secret. Subscribe now!

For more sports betting picks and tips

SportsbookWire.com and BetFTW. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:

BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWire | TitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire