First look: Miami at Louisville odds and lines

The 6th-ranked Miami Hurricanes (6-0, 2-0 ACC) travel to meet the unranked Louisville Cardinals (4-2, 2-1) Saturday at L&N Federal Credit Union Stadium. Kickoff is scheduled for noon ET (ABC/ESPN+). Below, we look at Miami vs. Louisville odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

The Hurricanes are coming off a bye following 2 wins with controversial finishes — at home against Virginia Tech and on the road at Cal. After opening the season 3-1 against the spread (ATS) in the first 4 games, the Hurricanes are 0-2 ATS in the past 2 outings. The Over has cashed at a 5-0-1 pace.

Louisville eased by Virginia 24-20 in Charlottesville Saturday, but it failed to cover as a 7-point favorite. After opening 3-0 ATS in the first 3 games, the Cardinals have failed to cover in the past 3 outings. The Cardinals are back home where they’re 3-1 SU/ATS in 4 games, with the Over going 3-1, too.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Miami at Louisville odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Monday at 7:07 a.m. ET.

• Moneyline (ML): Miami -175 (bet $175 to win $100) | Louisville +145 (bet $100 to win $145)
• Against the spread (ATS): Miami -4 (-110) | Louisville +4 (-110)
• Over/Under (O/U): 61.5 (O: -110 | U: -110)

2024 betting stats

• ML: Miami 6-0 | Louisville 4-2
• ATS: Miami 3-3 | Louisville 3-3
• O/U: Miami 5-0-1 | Louisville 4-2

Miami vs. Louisville head-to-head

Miami leads the all-time series 11-4-1, but the Cardinals won the most recent meeting 38-31 as a 1-point underdog at Hard Rock Stadium in Miami Gardens last November.

The last time these teams met in Louisville, the ‘Canes came away with a 47-34 win Sept. 19, 2020.

The Cardinals have won 4 of the past 6 meetings since Sept. 16, 2006, including a meeting in the 2013 Russell Athletic Bowl in Orlando.

Play our free daily Pick’em Challenge and win! Play now!

For more sports betting picks and tips

SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Clemson / Colorado / Duke / Florida / Florida State / Georgia / Iowa / Kentucky / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / UCLA / USC / Washington / Wisconsin / Recruiting / Transfer portal / College Football Playoffs / College Sports Wire / High School