San Francisco Giants at Cincinnati Reds odds, picks and predictions

The San Francisco Giants (54-56) and Cincinnati Reds (52-56) open a 3-game set at Great American Ball Park Friday. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 2-1

The Giants got back in the win column with a 1-0 victory over the visiting Oakland A’s Wednesday while cashing as -192 favorites. RHP Logan Webb pitched a shutout for the 2nd time in his career, and 2B Brett Wisely drove in the sole run of the game with a 5th-inning sacrifice fly.

The Reds snapped a 2-game winning streak with a 13-4 loss against the Chicago Cubs Wednesday as -150 home favorites. RF Jake Fraley hit a 3-run homer in the 5th inning, and LHP Nick Lodolo allowed 8 ER in 5 2/3 innings to pick up the loss.

Giants at Reds projected starters

LHP Kyle Harrison vs. LHP Andrew Abbott

Harrison (6-4, 3.69 ERA) makes his 19th start. He has a 1.28 WHIP, 3.04 BB/9 and 8.29 K/9 through 97 2/3 innings.

• Last start: Win, 6 2/3 IP, 1 ER, 1 H, 2 BB, 11 K in 11-4 home victory against Colorado Rockies Friday
• Career vs. Reds: 1-0, 2.38 ERA (11 1/3 IP, 3 ER), 1.15 WHIP, 12.7 K/9 in 2 starts, including 0-0 with 5.40 ERA (5 IP, 3 ER) in 1 start this year

Abbott (9-7, 3.38 ERA) makes his 22nd start. He has a 1.26 WHIP, 3.46 BB/9 and 6.85 K/9 through 117 innings.

• Last start: Loss, 4 IP, 4 ER, 8 H, 2 BB, 2 K in 4-0 loss at Tampa Bay Rays Saturday
• Career vs. Giants: 2-1, 2.76 ERA (16 1/3 IP, 5 ER), 1.10 WHIP, 7.7 K/9 in 3 starts, including 1-0 with 3.60 ERA (5 IP, 2 ER) in 1 start this season

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Giants at Reds odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:35 a.m. ET.

• Moneyline (ML): Giants -110 (bet $110 to win $100) | Reds -110 (bet $110 to win $100)
• Run line (RL)/Against the spread (ATS): Giants -1.5 (-155) | Reds +1.5 (-188)
• Over/Under (O/U): 9 (O: -120 | U: +100)

Giants at Reds picks and predictions

Prediction

Giants 3, Reds 2

BET GIANTS (-110).

The Giants are 6-2 in their last 8 games, including 5-1 in their last 6. They face a Reds team that is 2-3 in its last 5 games and has been inconsistent offensively. Cincinnati has scored 1 run or fewer in 2 of its last 5 games and 4 runs or fewer 3 times over that span. While Friday night should be a strong battle between 2 lefties, San Francisco holds the advantage.

PASS.

There is better value on the moneyline for San Francisco.

BET UNDER 9 (+100).

Harrison has allowed 1 ER or fewer in each of his last 3 starts. The Giants have hit the Under in 6 of their last 10 games overall, including 4 of their last 5. They’ve also scored 2 or fewer runs in back-to-back games.

The Reds have hit the Under in 7 of their last 10 games, including 5 of their last 6. They’ve scored 4 runs or fewer in 4 of their last 6 games.

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