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ScienceAlert


Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for  Parkinson's disease from cell-to-cell in the brain.
Promisingly, an FDA-approved  cancer drug that targets another protein called Lag3 – which interacts with Aplp1 – blocks the spread in mice, suggesting a potential therapy may already exist.



					
			

In a new paper, an international team of scientists describes how the two proteins work together to help harmful alpha-synuclein protein clumps get into brain cells.
"Now that we know how Aplp1 and Lag3 interact, we have a new way of understanding how alpha-synuclein contributes to...

Parkinson's Discovery Suggests We May Already Have an FDA-Approved Treatment

Daily Mail

Hopes that a treatment for Parkinson's is on the horizon have been raised after research suggested tetanus jabs guard against the incurable disease.

Parkinson's disease could be treated with tetanus jabs - after new research found those who had the shot were half as likely to be diagnosed with the condition

Thyroid dysfunction may lead to mental health symptoms like anxiety and brain fog. An overactive thyroid is more likely to cause these symptoms, and management typically involves regulating thyroid hormone levels. The thyroid gland produces hormones involved in important body functions, from your metabolism to cognitive tasks and mood regulation.

Thyroid Disease and Anxiety: Is There a Link?

LiveScience

By analyzing the proteins in the blood, a new blood test and AI tool can identify which at-risk patients are most likely to develop Parkinson's disease.

New blood test could flag Parkinson's disease years before symptoms, study hints

The thyroid makes hormones that help regulate critical body functions like growth and development, body temperature, heart rate, menstrual cycle and weight. If the thyroid becomes underactive and stops producing these hormones, it can spell serious trouble for our health. There are a few things that can cause an underactive...

Hashimoto’s: An often misdiagnosed thyroid disorder

Anxiety doesn’t directly cause IBS, but it may make your symptoms worse. Overlapping genetic pathways and two-way communication between your gut and your brain could help explain the link between these two conditions. It’s fairly common to notice gastrointestinal (GI) symptoms when you’re feeling anxious. Known as having a...

Your Guide to Navigating Anxiety and Irritable Bowel Syndrome

A major cause of inflammatory bowel disease (IBD) has been discovered by UK scientists. They found a weak spot in our DNA that is present in 95% of people with the disease. It makes it much easier for some immune cells to go haywire and drive excessive inflammation in the bowels.

Major cause of inflammatory bowel disease found

BuzzFeed News

After Taylor Swift and Kylie Jenner were called “climate criminals” for flying private, Jennifer Lopez is being widely mocked for taking a two-hour commercial flight.

People Are Defending Jennifer Lopez After She Was Brutally Dragged For Taking A Two-Hour Commercial Flight

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Total Apex Sports & Entertainment

People handle situations in different ways. Some zodiac signs are dramatic while others love peace. Someone can decide to never visit a salon again after they have a painful experience. Drama is part of life, but some people love exaggerating things. Their dramatic nature repels other signs who prefer addressing differences diplomatically.

3 Zodiac Signs Who Are The Most Dramatic

SurvivorNet

Former “Good Morning America” host Charlie Gibson, 81, was a fixture on TV sets for millions of Americans during the ‘80s and ‘90s; towards the end of his broadcast career, he became a cancer advocate.

Former ‘Good Morning America’ Host Charlie Gibson, 81, Anchorman to Cancer Advocate and, His Latest Project Getting Kids to Read

The early signs of dementia in women include memory loss and confusion. Dementia is a collective term that describes various symptoms of cognitive decline, such as forgetfulness, confusion, and changes in behavior. It is not a specific disease but a group of conditions characterized by impairment of at least two brain functions, such as memory loss and judgment.

Early signs of dementia in women

Deciding on which zodiac signs are the most dangerous is not an easy task as there could be many ways of determining what is considered dangerous. Dangerous of course could be a very subjective idea. Your own sign could also weigh heavily in making this list as certain signs, as we know, tend to be more compatible with some than others. So, what am I going to make these predictions based on? I am thinking that looking at the most formidable and dangerous people in our history might be a good way to make the determination of the most dangerous signs. Let’s see what we can learn.

3 Zodiac Signs That Are Born to be Bad

Although Kim Kardashian claims she has “no recollection” of dancing with Britney Spears’ manager, Cade Hudson, at Khloé Kardashian’s 40th birthday party, someone managed to record the interesting interaction and she posted it. In her Instagram Stories on Sunday, the reality TV star and Skims...

Kim Kardashian Gets Drunk, Dances With Britney Spears’ Manager in Wild Video

Stiff-person syndrome has gotten a lot of attention since Celine Dion announced in 2022 that she had been diagnosed with the neurological disorder. The iconic singer has made few public appearances and statements since then, but when she does it often raises questions about what stiff-person syndrome is and how it's treated.

Stiff-Person Syndrome Is More Painful Than You Think — Here's What to Know

Van Halen on stage on the 2004 Summer Tour (Photo by KMazur/WireImage for Van Halen) Former Van Halen frontman Sammy Hagar has reflected on the 2004 tour that saw him unite with the band after eight years – and it paints a sorry picture of Eddie Van Halen’s issues with addiction at the time. In a recent interview with AXS TV, Hagar even claims that his experience on 2004 Summer Tour was “the worst experience” of his life.

“It was horrible. He did horrible things to people” Sammy Hagar recalls what Eddie Van Halen was like on Van Halen’s 2004 World Tour

Back pain is a global problem, with estimates suggesting there are more than a half-billion cases worldwide. Although there are various causes of back pain, it often results from a traumatic event. You probably know the feeling: Bending over may send a shock of pain, standing too long causes a...

Walk Your Back Pain Away

Austin, TX

The Mirror US

Kelsey Riddle, 26, discovered she had cancer on her birthday as she was in the midst of crafting a thesis for her graduate program

Doctors told me my symptoms were allergies before I was diagnosed with cancer

Parkinson’s disease is a chronic brain disorder that leads to abnormal brain functions and can affect the nervous system. As a result, patients with Parkinson’s have issues with pain, movement, sleep, and mental health. Common symptoms include tremors, painful muscle contractions, stiffness, loss of balance, slow movement, reduced coordination, difficulty speaking, and others. Unfortunately, there is no cure for Parkinson’s and symptoms worsen over time. However, there are therapies that regulate symptoms to slow disease progression and improve quality of life.

Cancer Immunotherapy Applied to Parkinson's Disease

The US Sun

WENDY Williams had $55 million in the bank before her guardian, Sabrina Morrissey, took over and told her she had no money left, per court documents. In an affidavit submitted to a New Jersey court and exclusively obtained by The U.S. Sun, Wendy‘s best friend of 44 years, Regina Schell, claimed to have seen the […]

Wendy Williams ‘had $55m in bank’ before guardian took over & told her she had ‘no money’ left, court docs claim

Insider

I'm sober, and my husband still drinks. I was nervous to go to an all-inclusive resort together on vacation, but we both enjoyed our trip.

My husband and I went to an all-inclusive resort. He drinks, and I'm sober, but I didn't feel like I was missing out.

NewsBreak

Developing Anxiety After Age 50 Linked to Parkinson’s Disease

July 1, 2024 – Being diagnosed with an anxiety disorder later in life may mean up to a doubled risk of also getting Parkinson’s disease. Parkinson’s...

Developing Anxiety After Age 50 Linked to Parkinson’s Disease

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