Researchers Jenny Ting, PhD, the William Kenan Distinguished Professor of Genetics and professor microbiology and immunology at the UNC School of Medicine, and Kaixin Liang, PhD, a postdoctoral researcher in the Ting lab, have identified how the COVID-19 virus causes death in the cells lining the human airways. Their findings,...

COVID-19 Causes a “Cell Death Cascade” in Airway Cells

West Virginia State

Writers represent independent, third-party users who have joined our contributor program and self-verified their accounts. Writers are expected, like all users, to adhere to our Community Standards.

writer

Norfolk, VA

Cheryl E Preston

Four Virginians were confirmed to be onboard when the Titanic sank on April 14, 1912. Phillip Acts and Selini Decker, who lived a few blocks apart in Norfolk, died when the ship sank. Richmond native Robert Decker and Eloise Smith, who later moved to Richmond from West Virginia, survived.

There's a reason no remains from the Virginia Titanic victims will ever be found

KAUST’s NanoRanger provides quick, precise diagnosis of Mendelian genetic disorders, identifying critical genetic breakpoints efficiently. Despite rapid advances in genetic testing in recent decades, more than half of people worldwide with suspected Mendelian genetic disorders do not have an accurate molecular diagnosis. Others endure more than six years of tests before a diagnosis is given. Now, KAUST researchers and scientists across Saudi Arabia have developed NanoRanger, an accurate and rapid method for genetically diagnosing such diseases in a few hours.

NanoRanger Redefines Speed and Precision in Genetic Diagnostics

Chicago, IL

Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Soft drinks often contain a key ingredient, such as caffeine, and one or more additives, such as benzoate or sorbate (as preservatives), and/or acesulfame K, saccharin, or aspartame (as artificial sweeteners). Aspartame is prone to degradation once in solution. Its degradation products could interfere with the quantification of other additives.

HPLC Analysis of Soft Drinks Using Alliance™ iS HPLC System

Austin, TX

The Next-Generation Microelectronics Manufacturing program, known as NGMM, aims to unlock accessible prototyping for the chips of tomorrow with a new agreement to establish the first-ever national center for advancing U.S.-based microelectronics manufacturing. DARPA will work with the University of Texas at Austin and its existing Texas Institute for Electronics...

DARPA Establishing National Center for Advancing U.S.-Based Microelectronics Manufacturing

The majority of rare diseases have a genetic cause. The underlying genetic alteration can be found more and more easily, for example by means of exome sequencing (ES), leading to a molecular genetic diagnosis. ES is an examination of all sections of our genetic material (DNA) that code for proteins. As part of a Germany-wide multicenter study, ES data was collected from 1,577 patients and systematically evaluated. This made it possible to diagnose a total of 499 patients, with 34 patients showing new, previously unknown genetic diseases. The study thus makes a significant contribution to the initial description of new diseases. In addition, software based on the use of artificial intelligence (AI) was used for the first time on a broad scale to support clinical diagnosis. The "GestaltMatcher" AI system can assist in the assessment of facial features with regard to the classification of congenital genetic syndromes. The results of the study, in which 16 universities and university hospitals were involved, including the University of Bonn, have now been published in the renowned journal "Nature Genetics".

Study of 1,577 Patients Identifies 34 New Genetic Diseases

Most robotic systems developed to date can either tackle a specific task with high precision or complete a range of simpler tasks with low precision. For instance, some industrial robots can complete specific manufacturing tasks very well but cannot easily adapt to new tasks. On the other hand, flexible robots designed to handle a variety of objects often lack the accuracy necessary to be deployed in practical settings.

New learning-based method trains robots to reliably pick up and place objects

Over the last 40 years, molecular blood-based biomarkers have become increasingly important in the diagnosis, treatment and management of disease. In particular, the last decade has seen a rapid increase in the number of DNA-related tests, fueled by the revolution in DNA sequencing which has dramatically reduced costs such that a full genome can be sequenced for a few hundred dollars.

Leveraging Proteomics for Clinical Biomarker Discovery

The immune system defends the body against invading bacteria and viruses, as well as the spread of tumor cells. Unfortunately, the necessary immune response of the body causes unwanted damage that the body must heal. After combating these dangers, the immune system needs to be dampened again, otherwise, persistent inflammation or even the development of an autoimmune disease can occur. The reduction of the immune response and the initiation of tissue healing is partly achieved by tissue-resident immune cells, in particular regulatory T cells. However, it has not yet been sufficiently researched how tissue-resident immune cells differ from immune cells in the blood and whether different immune cell types in the tissue undergo common adaptation programs.

“Jumping Genes” Help Regulate Tissue-Residing Immune Cells

Research shows humans often perceive attractive people as more intelligent, healthier, better leaders and more trustworthy. It turns out this bias extends to the insect world. A new study by scientists at the USC Dornsife College of Letters, Arts and Sciences reveals that data reported on a popular community science platform is biased. On iNaturalist, butterflies with captivating markings, easily identifiable features or those that are familiar species are reported more frequently than obscure species with no distinct qualities.

Researchers Appeal to Community Scientists To Take Pictures of Ugly Butterflies, Too

The SPIRA-A integrated fixation system is an anterior lumbar interbody fusion device with an open matrix design. Camber Spine has earned U.S. Food and Drug Administration (FDA) 510(k) clearance for its SPIRA-A integrated technology. SPIRA-A Integrated is now indicated for one or more levels from L1-S1 as an adjunct to...

FDA Clears Camber Spine's SPIRA-A Integrated ALIF

Cancer cells can hijack cell cycles to exponentially increase their numbers, a process called proliferation. Cancer drugs can stop the growth of cancer cells by jumpstarting a complex chain of genetic and cellular events. But often, this story is more complex, involving treatments that don’t work as well as had been hoped.

How Do Cancer Cells Divide Despite Treatment?

Better understanding of this natural formation process offers potential for technical developments. A new interdisciplinary study led by molecular biologist Florian Raible from the Max Perutz Labs at the University of Vienna provides exciting insights into the bristles of the marine annelid worm Platynereis dumerilii. Specialized cells, so-called chaetoblasts, control the formation of the bristles. Their mode of operation is astonishingly similar to that of a technical 3D printer. The project is a collaboration with researchers from the University of Helsinki, Vienna University of Technology and Masaryk University in Brno. The study was recently published in the renowned journal Nature Communications.

Nature’s Precision 3D Printer: The Artful Construction of Worm Bristles

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD). The study, recently published in Nature Communications, demonstrates the effectiveness of their novel gene...

Gene Therapy Approach Shows Promise for Muscular Dystrophy

The Associated Press

CHICAGO--(BUSINESS WIRE)--Jul 24, 2024-- ADLM 2024 Clinical Lab Expo--Siemens Healthineers has pushed the boundaries of medical engineering to improve patient care for more than 125 years. At the ADLM 2024 Clinical Lab Expo (from July 30-Aug. 1 at McCormick Place, Chicago, Booth #501), Siemens Healthineers will demonstrate what’s achievable for laboratory testing with human-centered engineering and automation. New capabilities from Siemens Healthineers bring unmatched automation to laboratories of all sizes. Enhancements to the Atellica Portfolio underscore sustainability, leading workflow efficiency, AI-enabled intelligence, and advanced analytics to turn data into practical clinical insights. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20240724071941/en/ (Graphic: Business Wire)

Human-Centered Engineering in the Lab Can Close the Distance Between Providers and Care: Siemens Healthineers to Exhibit How at ADLM 2024

USC scientists have discovered a way to turn the body’s B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine’s most formidable foes. The research, published Monday in Nature Biomedical Engineering, describes a...

Researchers Turn B Cells Into Antibody Factories To Combat HIV and Cancer

AMBOTS, a spin-off from the AM3 Lab at the University of Arkansas, was established with the goal of achieving fully autonomous manufacturing, in contrast to today’s automated but repetitive processes. The company envisions a future where custom-designed products are 3D printed on demand at low cost through a process known as swarm manufacturing. In an interview with 3Druck.com, founder Wenchao Zhou gives an insight into additive manufacturing with mobile 3D printing robots.

From assembly line to swarm manufacturing with 3D printing robots – Interview with AMBOTS founder Wenchao Zhou

When picturing next-generation wearables and robotics, the foam filling in your couch cushions is likely not the first thing that comes to mind. However, Rice University engineers have shown that something as simple as the flow of air through the airy, meshlike structure of open-cell foam can be used to perform digital computation, analog sensing and combined digital-analog control in soft textile-based wearable systems.

Foam fluidics showcase team's creative approach to circuit design

Denver, CO

Forging lead times present an obstacle the U.S. Navy wishes to overcome in obtaining the projectile housings for artillery rounds, says Big Metal Additive. The company has developed and proven out a process using directed energy deposition (DED) via a robot to make these housings through additive manufacturing. One robot and one lathe can produce housings at the rate of six per day, and the company is getting ready for an eventual AM factory that will make these rounds by the hundreds per day. I learned more about this work during a visit to Big Metal Additive in Denver, Colorado.

Video: 5" Diameter Navy Artillery Rounds Made Through Robot DED Instead of Forging

NewsBreak

New Bioprinting Technology Paves Way for Human-Compatible 3D-Printed Organs

A research team at the University of Virginia School of Engineering and Applied Science has developed what it believes could be the template for the first...

New Bioprinting Technology Paves Way for Human-Compatible 3D-Printed Organs

Comments / 0