The FDA on Thursday signed off on Citius Pharmaceuticals’ Lymphir (denileukin diftitox-cxdl) for the treatment of patients with relapsed or refractory cutaneous T cell lymphoma, who have undergone at least one prior line of systemic therapy. Lymphir is Citius’ first FDA-approved product and currently the only treatment for cutaneous...

Citius Scores FDA Approval in Cutaneous T Cell Lymphoma

Servier has expanded its IDH drug armamentarium with the FDA approval for an IDH1/2 dual inhibitor. The approval represents the first major treatment advance in low-grade brain cancer in more than two decades. The new FDA approval is for Servier’s Voranigo, or vorasidenib, for adult and children ages 12 and...

Servier snags FDA approval for Voranigo, the first targeted therapy for a common type of brain tumor

Investigators assessed alemtuzumab plus UCART22 in relapsed/refractory B-cell acute lymphoblastic leukemia as part of the phase 1 BALLI-01 trial. The FDA has granted orphan drug designation to the investigational agent alemtuzumab (CLLS52) in the treatment of patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL), according to a press release from the developer, Cellectis.1.

Lymphodepleting Alemtuzumab Earns FDA Orphan Drug Status in R/R B-ALL

Cancer Health

FDA approves vorasidenib for Grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation. On August 6, 2024, the Food and Drug Administration approved vorasidenib (Voranigo, Servier Pharmaceuticals LLC), an isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor, for adult and pediatric patients 12 years and older with Grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation, following surgery including biopsy, sub-total resection, or gross total resection.

FDA Approves New Targeted Therapy for Brain Cancer

The U.S. Food and Drug Administration (FDA) has approved IPX203, a novel extended-release formulation of levodopa and carbidopa, for Parkinson’s disease. Amneal Pharmaceuticals will be marketing the newly approved therapy under the brand name Crexont, which is expected to be available to patients in the U.S. in September. “The...

FDA approves extended-release levodopa/carbidopa, now Crexont

Chicago, IL

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Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

The Hill

The Food and Drug Administration approved the first needle-free alternative to the EpiPen on Friday, a single-use epinephrine nasal spray for the emergency treatment of allergic reactions, including anaphylaxis. The agency said it approved Neffy, from ARS Pharmaceuticals, for use in adult and pediatric patients who weigh at least 30...

FDA approves epinephrine nasal spray, a needle-free alternative to EpiPen

WEDNESDAY, Aug. 7, 2024 (HealthDay News) — For patients with preoperative iron deficiency anemia (IDA), intravenous (IV) iron treatment is associated with a significant reduction in 30-day postoperative mortality and morbidity compared with red blood cell (RBC) transfusion, according to research published online July 22 in Anesthesia & Analgesia.

Preoperative IV Iron Treatment Better for Iron Deficiency Anemia

The National Comprehensive Cancer Network now recommends Rytelo for patients with myelodysplastic syndrome who require blood transfusions. The National Comprehensive Cancer Network (NCCN) now recommends Rytelo (imetelstat) as a treatment for patients with lower-risk myelodysplastic syndrome (MDS) who have symptomatic anemia. The NCCN is comprised of leading oncology centers. They...

NCCN Recommends Rytelo for Anemia in Patients With MDS

Ohio State

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The Lantern

On Tuesday, licensed Ohio dispensaries began legally selling non-medical marijuana to consumers; however, the drug’s possession, growth and/or usage are still prohibited on Ohio State’s campus. Credit: Jefferee Woo/Tampa Bay Times/TNS [Original caption: Four citizen-led petitions with proposals to update Dallas’ charter hit the 20,000 valid signature threshold to make it on the Nov. 5 election ballot, including one that would ban police officers from arresting or citing people carrying less than four ounces of marijuana.] As of Tuesday, students 21 and older can now legally purchase marijuana in Ohio.

Dispensary sales of recreational marijuana began Tuesday; possession and usage still prohibited on Ohio State’s campus

Sanford, FL

Akeena

Soul food, a favorite from the South, is loved by many Floridians who used to live up North. Florida is home to popular soul food places like Seth's and Happy Soul. Unfortunately, another favorite, Angel's Soul Food in Sanford, has been closed after a state inspection.

Florida soul food restaurant found with debris, "Mold-Like" substance, and raw sewage on the floor

South Carolina State

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Explore Beaufort SC

The mantis shrimp is one tough customer. Beautiful and deadly are two words you don’t typically use to describe shrimp, but the mantis shrimp is definitely in a class of its own; earning a reputation as the ‘savage boxer of the sea’ and one of the most fearsome creatures in the ocean. And, they're right at home here in South Carolina.

Savage Boxer of the Sea: The Deadly Beauty of Mantis Shrimp

Newark, NJ

Morristown Minute

NEWARK, N.J. – An Essex County man has been charged with numerous offenses related to narcotics distribution and firearms trafficking. Kyrell Domnie, 39, of Irvington, known by the alias "Fly Ky," was charged by complaint and appeared before U.S. Magistrate Judge Cathy L. Waldor in Newark federal court on July 17, 2024. He remains detained following the hearing.

Convicted Felon Faces Multiple Narcotics and Firearms Charges

Colorado State

David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Dr. Qin Rao, an ABMS board certified internal medicine physician specializing in gastroenterology and hepatology, spoke with Healthline about when people with ulcerative colitis (UC) might consider biologic therapy to manage their condition. What are biologics, and how do they work for ulcerative colitis?. Biologics are medications, usually given as...

An Expert Explains When to Consider Biologics for Ulcerative Colitis (UC)

M Henderson

Here's another recipe for fudge that's very easy to make. You can double it, or quadruple it, for more servings. 4 tablespoons cocoa or cacao powder (I like 2 tablespoons of each)

3-Ingredient Fudge

Georgia State

Appling County, GA

Daily Coffee Press

A 40-year-old man from Appling County, Christopher Eric Stone, with a significant criminal history, was recently sentenced to over five years in prison after pleading guilty to possession of methamphetamine with intent to distribute, according to officials from the Department of Justice.

Georgia Man Sentenced to Over 5 Years for in Federal Prison for Meth Distribution

Denver, CO

More dangerous substances are entering the Denver drug supply, Harm Reduction Action Center warned in a newsletter this week. “The Iron Law of Prohibition posits that as law enforcement becomes more intense, the potency of prohibited substances increases,” HRAC Executive Director Lisa Raville wrote in the newsletter. That is exactly what is happening, she said.

Dangerous substances entering Denver drug supply

Tennessee State

John M. Dabbs

NASHVILLE, Tenn. — The Tennessee Department of Health (TDH) has issued a health alert to clinicians statewide following reports of severe acute illnesses and adverse effects of consuming Diamond Shruumz™ brand chocolate bars, cones, and gummies. The warning comes after the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) received reports of serious health issues linked to these mushroom-containing edible products.

Tennessee Health Alert: Severe Illnesses Linked to Diamond Shruumz™ Products

Florida State

Who would have thought that a chain known for its endless shrimp promotion could find itself in such a pickle? But here we are—Florida-based Red Lobster, which has been reeling from financial troubles, may have finally found a lifeline. After a surprising $11 million loss in the third quarter of 2023 due to that very shrimp deal, Red Lobster filed for bankruptcy in May 2024. And now, there’s a glimmer of hope on the horizon.

A Florida based chain that filed for bankruptcy has reportedly found a potential buyer

NewsBreak

FDA Approves Improved Denileukin Diftitox in Cutaneous T-Cell Lymphoma

Following voluntary withdrawal in 2014, denileukin diftitox is now available again for the treatment of patients with cutaneous T-cell lymphoma who have received at least 1...

FDA Approves Improved Denileukin Diftitox in Cutaneous T-Cell Lymphoma

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