A multicenter, randomized, double-blind, placebo-controlled trial done performed in the the United Kingdom June 2014 to October 2017), enrolled 207 adult patients with symptomatic, radiographic KOA and knee pain (severity ≥4 out of 10) on most days in the past 3 months, after an inadequate response to analgesic medications.

Pain Reduction with Methotrexate in Knee Osteoarthritis

Kansas City, MO

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Kentucky Vibes.net

Disclaimer: This article was written with the help of A.I. software. Kansas City Chiefs quarterback Patrick Mahomes, known for his prowess on the football field, made a personal announcement during a press conference on Tuesday. The three-time Super Bowl champion revealed that he and his wife, Brittany Mahomes, are expecting their third child and that this will be their last.

Patrick Mahomes Reveals He's 'Done' Having Kids with Wife Brittany Mahomes After Baby No. 3

Developed by Vertex Pharmaceuticals, suzetrigine is a promising new class of pain medicine that has been gaining attention for its innovative mechanism of action and reported efficacy; suzetrigine might offer hope for those struggling with acute pain issues who want to avoid opioids and NSAIDs. The reliance on opioids and...

A New Class of Medicine for Pain Relief On The Horizon

Ohio State

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The Lantern

On Tuesday, licensed Ohio dispensaries began legally selling non-medical marijuana to consumers; however, the drug’s possession, growth and/or usage are still prohibited on Ohio State’s campus. Credit: Jefferee Woo/Tampa Bay Times/TNS [Original caption: Four citizen-led petitions with proposals to update Dallas’ charter hit the 20,000 valid signature threshold to make it on the Nov. 5 election ballot, including one that would ban police officers from arresting or citing people carrying less than four ounces of marijuana.] As of Tuesday, students 21 and older can now legally purchase marijuana in Ohio.

Dispensary sales of recreational marijuana began Tuesday; possession and usage still prohibited on Ohio State’s campus

Orlando, FL

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Akeena

If you’ve been enjoying the vibrant food scene in Thornton Park, you might have heard some bittersweet news—Graffiti Junktion, the spot known for its top-notch burgers and laid-back vibe, has officially closed. After 16 years of serving up some of the best burgers in Orlando, the eatery has said its goodbyes. Here’s a closer look at why this cherished spot is shutting down and what it means for the community.

Favorite Florida Burger Place Closed Because Wages and Costs Went Up

Herbie J Pilato

Actor Clarence Williams III, best known as the super cool undercover cop Lincoln "Linc" Hayes on TV's classic crime drama, The Mod Squad, died three years ago from colon cancer at 81 years old. This is the story of a talent that lives on.

The Tragic Death of 'Mod Squad'/'Purple Rain' Actor Clarence Williams III: Three Years Later

Florida State

Red Lobster, the popular seafood chain, has confirmed additional closures in Florida, adding to its recent wave of shutdowns following the company’s bankruptcy filing in May. The latest round of closures includes two more Florida locations, highlighting the ongoing struggles of the iconic restaurant chain.

Popular seafood chain announces more closures in Florida

NBC News

The Food and Drug Administration has approved ARS Pharmaceuticals’ nasal spray as the first needle-free emergency treatment for potentially fatal allergic reactions, the agency said on Friday. The spray, which will be sold under the brand name Neffy, is seen as an alternative to EpiPen and other autoinjectors like...

FDA approves nasal spray as first needle-free treatment for anaphylaxis

WASHINGTON - On Friday, the U.S. Food and Drug Administration approved a nasal spray for the emergency treatment of allergic reactions – the first needle-free alternative to shots like EpiPen. The nasal spray, marked as neffy, is intended as an emergency treatment for adult and pediatric patients who weigh...

FDA approves neffy nasal spray as alternative to EpiPen

After being forced to cancel recent tour performances, famed Guns N' Roses guitarist Slash, who just turned 59, shared the tragic news that led to his decision:. The music legend took to social media on July 22, 2024, mentioning the death of his stepdaughter Lucy-Bleu Knight.

Legendary Rock Guitarist Slash Turns 59 and Cancels Tour Amid the Tragic Death of His Stepdaughter

Two premature babies died within weeks of each other after neglect by a hospital, an inquest jury has found. Westminster Coroners’ Court heard Elena Ali and Sunny Parker-Propst were both given sodium nitrite instead of sodium bicarbonate in 2020 while under the care of staff at Chelsea and Westminster Hospital.

Babies died after hospital neglect - inquest jury

Actor Buddy Ebsen, who died at age 95 in 2003, found fame by starring in two of the most popular classic television shows in history: The Beverly Hillbillies (CBS, 1962 to 1971) and Barnaby Jones (CBS, 1973 to 1980). On the Hillbillies, he played former Tennessee country mountain-folk-turned-wealthy Beverly Hills resident Jed Clampett. On Barnaby Jones, he was one of TV's most senior, slyest, health-conscious detectives. Ebsen, however, almost became even more famous for a certain big-screen classic film in which he ultimately did not appear.

'Beverly Hillbillies" Actor Buddy Ebsen Was "Bitter" about not playing the Tin Man in 'Wizard of Oz'

Lake Mary, FL

If you're a fan of hearty breakfasts and brunches in Florida, you might have had Keke’s Cafe on your radar. Known for its generous portions and friendly service, Keke’s has been a go-to spot for many. However, the Lake Mary location recently hit a bump in the road, resulting in a temporary shutdown following a state inspection that uncovered 15 violations.

Breakfast Eatery Closed in Florida for Roaches, Dirty Hands, and Cold Foods Over 41 Degrees

Interesting Engineering

Patients experienced a significant reduction in pain, improved their quality of life, and even showed signs of cartilage regrowth.

Stem cell shot reverses osteoarthritis, repairs knee cartilage, cuts pain by 58%

Learn more about canine elbow dysplasia, and how to treat it in this week's episode of The Vet Blast Podcast. On this week's episode of The Vet Blast Podcast, our host Adam Christman, DVM, MBA, and special guest David L. Dycus, DVM, MS, CCRP, DACVS (Small Animal), break down managing canine dyspaslia with an emphasis on the importance of a multimodal approach. Throughout the episode, Dycus and Christman highlight treatment options, including new options, conservative management, and when a surgical intervention could be needed.

What do you know about canine elbow dysplasia?

Chicago, IL

Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Georgia State

Tallahassee, FL

Daily Coffee Press

The FBI is investigating the disappearance of a now 13-year-old girl who went missing from Florida last year and has ties to Georgia and Tennessee. A $15,000 reward is being offered to anyone with information that can lead to her location.

FBI Investigating Disappearance of 12-Year-Old Girl Who Has Ties to Georgia

Chronic pain, particularly neuropathic pain resulting from nerve damage, significantly impacts quality of life for many individuals. Conventional treatments, such as opioids, often come with severe side effects like addiction, tolerance, and constipation, making them less ideal for long-term management. Recent research published in the journal PAIN explores an alternative:...

Cannabis terpenes offer new hope for neuropathic pain relief

South Carolina State

Explore Beaufort SC

The mantis shrimp is one tough customer. Beautiful and deadly are two words you don’t typically use to describe shrimp, but the mantis shrimp is definitely in a class of its own; earning a reputation as the ‘savage boxer of the sea’ and one of the most fearsome creatures in the ocean. And, they're right at home here in South Carolina.

Savage Boxer of the Sea: The Deadly Beauty of Mantis Shrimp

ABC News

The FDA rejected an application for the drug MDMA, in combination with therapy, as treatment for PTSD on Friday.

FDA rejects MDMA in combination with therapy as treatment for PTSD

NewsBreak

Pain relief for koalas: a study on acetaminophen use

What analgesics can be given to a koala? A study conducted by investigators in Australia has your answers. Koalas are accident prone marsupials. Many of them...

Pain relief for koalas: a study on acetaminophen use

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