Arizona Diamondbacks at San Diego Padres odds, picks and predictions

The Arizona Diamondbacks (43-44) open a 3-game road series against the San Diego Padres (48-43) Friday. First pitch from Petco Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 4-3

The Diamondbacks are coming off a series win on the road over the Los Angeles Dodgers. They won the finale 9-3 Thursday behind 1B Christian Walker ‘s 2 homers and a 4-run 9th inning to blow the game open. They have won 4 of their last 5 games.

The Padres are 11-3 since losing 5 straight games June 14-18. They went 4-2 on their 6-game road trip and won the final 2 games of a series against the Texas Rangers, beating them 3-1 Thursday.

Diamondbacks at Padres projected starters

RHP Slade Cecconi vs. RHP Randy Vasquez

Cecconi (2-6, 5.81 ERA) makes his 12th start and 13th appearance. The rookie has a 1.26 WHIP, 1.7 BB/9 and 7.5 K/9 in 57 1/3 innings.

• Last start: No-decision, 4 IP, 3 ER, 5 H, 2 BB, 7 K in 9-4 home loss to Oakland A’s June 28
• 2024 vs. Padres: 0-1, 9.35 ERA (8 2/3 IP, 9 ER), 1.73 WHIP, 7.3 K/9 in 2 starts
• Career vs. Padres: 0-1, 7.84 ERA (10 1/3 IP, 9 ER), 1.55 WHIP, 7.0 K/9 in 3 appearances (2 starts)

Vasquez (2-4, 4.88 ERA) makes his 12th start. The rookie has a 1.67 WHIP, 2.3 BB/9 and 5.6 K/9 in 51 2/3 innings.

• Last start: No-decision, 4 IP, 1 ER, 5 H, 1 BB, 1 K in 9-2 road win over Boston Red Sox June 28
• Went 2-1 with 4.20 ERA in 6 June starts
• 2024 vs. Diamondbacks: 0-0, 4.05 ERA (6 2/3 IP, 3 ER), 6 H, 0 BB, 3 K in 1 start, a 4-3 home loss June 6
• Career vs. Diamondbacks: 0-0, 5.00 ERA (9 IP, 5 ER), 1.22 WHIP, 5.0 K/9 in 2 appearances (1 start)

Who’s going yard ? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Padres odds

Provided by BetMGM Sportsbook ; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:17 p.m. ET.

• Moneyline (ML) : Diamondbacks -115 (bet $115 to win $105) | Padres -105 (bet $105 to win $100)
• Run line (RL)/Against the spread (ATS) : Diamondbacks -1.5 (+145) | Padres +1.5 (-175)
• Over/Under (O/U) : 8.5 (O: -110 | U: -110)

Diamondbacks at Padres picks and predictions

Prediction

Padres 6, Diamondbacks 4

Moneyline

The Diamondbacks have lost their last 2 series openers. They are 21-23 on the road this season.

The PADRES ( -105 ) are 24-22 at home this season but are 9-1 in their last 10 games at Petco Park. They have won 3 of the last 4 starts for Vasquez.

The Diamondbacks are 1-3 in Cecconi’s last 4 outings.

BET PADRES ( -105 ).

Run line/Against the spread

The last 10 times the Padres covered the spread, they won the game outright.

So at -175 odds for them to cover the +1.5, you’re better off going with the moneyline.

PASS .

Over/Under

Five of the 7 games between the teams this season have had double-digit runs, including 3 of the 4 in San Diego June 6-9.

Vasquez’s last 3 starts and 4 of his last 6 have had totals of 10 or more.

The Diamondbacks have scored 5 or more runs in 4 straight games and 21 runs in the last 2 games alone.

Nine of the Padres’ last 10 wins have had more than 8 total runs.

BET OVER 8.5 ( -110 ).

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