Columbus, OH

An overview of the complex relationships between herpes simplex virus, human papillomavirus, cytomegalovirus and HIV. Chronic viral infections from diseases such as between herpes simplex virus (HSV), human papillomavirus (HPV) and cytomegalovirus (CMV) can have a serious impact on those with immune systems already compromised by HIV, according to a session held today at the International AIDS Conference in Munich, Germany. The session featured three speakers who discussed each of these diseases.

Chronic Viral Infections Common in Those with HIV | AIDS 2024

A Year of Hepatitis Advances to Mark World Hepatitis Day. Viral hepatitis affects the lives of about one in twenty people in the world, resulting in over a million deaths each year. NIAID is working on many ways to prevent and treat the different types of hepatitis, including the development of vaccines and improved therapeutics and diagnostics.

NIAID Research to Eliminate the Threat of Viral Hepatitis Across the Globe

Lenacapavir (Sunlenca), Gilead Sciences’ twice-yearly capsid inhibitor, demonstrated 100% efficacy for HIV prevention in a large study of young cisgender women in Africa. Oral PrEP is highly effective for people who can take it consistently, but additional options are still needed for people who have difficulty using daily pills. The Phase III PURPOSE 1 trial enrolled more than 5,300 women in South Africa and Uganda. They were randomly assigned to receive injectable lenacapavir once every six months or the daily PrEP pills Descovy (tenofovir alafenamide/emtricitabine) or Truvada (tenofovir disoproxil fumarate/emtricitabine) in a 2:2:1 ratio. There were zero new infections in the lenacapavir group, 39 in the Descovy group and 16 in the Truvada group. All three PrEP methods were well tolerated, and no new safety concerns were identified. A parallel study (PURPOSE 2) is testing lenacapavir PrEP for cisgender and transgender men, trans women and nonbinary people in the United States and six other countries; results are expected in late 2024 or early 2025.

Prevention: Twice-Yearly PrEP

Current or previous use of the antiretroviral drug abacavir was associated with an elevated risk of major adverse cardiovascular events (MACE) in people with HIV, according to an exploratory analysis from a large international clinical trial primarily funded by the National Institutes of Health (NIH). There was no elevated MACE risk for the other antiretroviral drugs included in the analysis. The findings will be presented at the 2024 International AIDS Conference (AIDS 2024) in Munich, Germany.

Exploratory Analysis Associates HIV Drug Abacavir With Elevated Cardiovascular Disease Risk

San Francisco, CA

Long-acting injectable antiretrovirals can be a feasible treatment or prevention option for homeless and unstably housed people who have trouble using daily pills. A pilot study looked at 33 people who started HIV treatment or pre-exposure prophylaxis (PrEP) at the Maria X. Martinez Health Resource Center in San Francisco, which provides low-barrier care augmented by satellite sites and street medicine teams that deliver injections at syringe access programs, shelters and tent encampments. Most used drugs, primarily methamphetamine, and mental health problems were common. Of the 18 people with HIV—including 14 with a detectable viral load—most received Cabenuva (long-acting cabotegravir and rilpivirine) monthly or every other month, but four used injectable cabotegravir plus lenacapavir. All but one achieved or maintained viral suppression. In addition, 15 people started Apretude (injectable cabotegravir alone) for PrEP. All remained HIV negative. Adherence was good, with just 8% of scheduled injections delayed more than a week.

Treatment: Long-Acting Injectables

Christian Azubike Enwuru1, Adenike Shola Aiyedobgon2, Morakinyo Bamikole Ajayi1 &. BMC Women's Health volume 24, Article number: 415 (2024) Cite this article. This study was undertaken to determine the prevalence of Bacterial Vaginosis (BV), Trichomonas Vaginalis (TV) co-infection, and the antibacterial sensitivity profile of bacterial isolates. Methods. The study was...

Bacterial vaginosis (BV) and Trichomonas vaginalis (TV) co-infection, and bacterial antibiogram profile of pregnant women studied in Lagos, Nigeria

Antiretroviral therapy (ART) has been a game-changer for people with HIV. But HIV is skilled at “hiding” and can reappear in the blood stream shortly after ART is stopped. That’s why NIAID and partners are investigating strategies to completely clear HIV from a person’s body, effectively curing them, or to reduce it to levels that can be suppressed by their own immune systems.

Broadly Neutralizing Antibodies Evaluated in Many HIV Cure Strategies

Austin, TX

AIDS Healthcare Foundation (AHF) opened a new HIV clinic in Austin, Texas, that provides comprehensive care, including HIV testing, treatment, medical services, a pharmacy and services related to sexually transmitted infections (STIs), reports Fox 7. Austin Mayor Kirk Watson joined other local and state officials at the Friday ribbon cutting....

HIV Health Care Center Opens in Austin, Texas [VIDEO]

Miami, FL

Lamar McMullen of Miami is positively evangelical about long-acting injectables for HIV treatment. Currently, only one such medication is approved for injection every other month; others in the pipeline are intended to last even longer. Since giving up his once-a-day pill for a long-acting injectable, McMullen has been pleased with the results.

Getting Comfortable With Long-Acting Injectables

The immune system senses and responds to changes in physiologic health, and a new tool called the immune health metric (IHM) can measure and even predict some of these changes, an NIAID study has found. If doctors could use the IHM to detect health problems long before symptoms appear, they could potentially act early to prevent disease, the investigators suggest. Their findings are published in the journal Nature Medicine.

A New Way to Measure and Predict Human Immune Health

Strong bones help maintain mobility and enhance quality of life. People with HIV are more prone to bone loss and fractures, but you can take steps to improve bone health. Bone is living tissue largely made up of minerals and collagen. Cells called osteoblasts continually add new bone tissue, while osteoclasts dissolve old bone. As people age, bone resorption starts to outpace bone formation, and bone mass naturally declines. Osteopenia is an earlier stage of bone loss, which can progress to osteoporosis.

HIV and Your Bones

Los Angeles, CA

The Wall Las Memorias (TWLM), which provides health and wellness services to Latino, LGBTQ and other underserved populations, hosted a grand opening for its new Downtown Los Angeles (DTLA) Hub with a ribbon-cutting ceremony and open house. The new office is the group’s third and its second in downtown Los...

The Wall Las Memorias Opens a New Health and HIV Center in Downtown Los Angeles

Cardiovascular complications are among the most common comorbidities affecting people with HIV (PWH), with studies showing increased risk for myocardial infarction, heart failure, and sudden cardiac death in these individuals despite treatment with antiretroviral therapy (ART).1 Compared with people without HIV, PWH have demonstrated up to twice the risk for cardiovascular disease,2 and this difference is not clearly linked to traditional risk factors or ART.1.

Reducing the Risk of CVD in Patients with HIV

Everyday Health

Learn about eosinophilic esophagitis (EoE) and its symptoms, including chronic cough, treatment options, and diagnosis methods.

Can Eosinophilic Esophagitis Be the Reason Behind Your Chronic Cough?

Indiana State

Eighteen people living with HIV in Indiana were arrested between 2001 and 2019 for donating plasma, though, thanks to effective screening methods, none of them posed a risk of transmitting the virus, found a new report by the Williams Institute. The Williams Institute is a research center focusing on law...

People With HIV Have Been Arrested in Indiana for Donating Plasma

Medical News Today

Recent research from Italy suggests that high adherence to a Mediterranean-style diet is linked to a lower risk of death from all causes, and especially death from cardiovascular disease, in long-term cancer survivors.

Mediterranean diet may help boost longevity in cancer survivors

Autism spectrum disorder risk was similar with prenatal topiramate or lamotrigine vs. no antiseizure medication exposure. Prenatal valproate was tied to a dose-dependent increased autism spectrum disorder risk. Autism spectrum disorder incidence was higher for children with prenatal exposure to antiseizure medications vs. the general population, but some associations weakened...

Childhood autism may be linked to prenatal exposure to antiseizure medication

Colorado State

Contributors represent independent, third-party users who have joined our contributor program and self-verified their accounts. They have also demonstrated their experience writing hard news for other outlets. Contributors are expected, like all users, to adhere to our Community Standards.

contributor

David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Georgia State

Atlanta, GA

Daily Coffee Press

A 40-year-old man has been sentenced to over 28 years in prison for distributing significant amounts of fentanyl and other controlled substances to dealers in the Middle Georgia region. Authorities revealed that investigators uncovered evidence linking the drugs provided by the defendant, 40-year-old Lagary Williams, also known as "Frog," from Atlanta, to a fatal overdose.

Atlanta Man Sentenced to 28 Years for Supplying Deadly Fentanyl Linked to Fatal Overdose

5 – The Well Project launches a mobile app that includes treatment information and highlights the firsthand experiences of women living with the virus. (2012) 15 – The Congressional HIV/AIDS Caucus is founded. (2011) 17 – The Centers for Disease Control and Prevention launches the HIV awareness campaign...

Everyday – September 2024

NewsBreak

Long-Acting Injectable Cabotegravir for HIV Prevention is Safe in Pregnancy

Long-acting injectable cabotegravir (CAB-LA) was safe and well tolerated as HIV pre-exposure prophylaxis (PrEP) before and during pregnancy in the follow-up phase of a global study...

Long-Acting Injectable Cabotegravir for HIV Prevention is Safe in Pregnancy

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