Columbus, OH

A unique HIV cure case will be among the scientific highlights of AIDS 2024, the 25th International AIDS Conference, which will take place in Munich, Germany and virtually from 22 to 26 July. For the first time, scientists will share information about the “next Berlin Patient”, who appears to be...

First-of-its-kind HIV Cure Case Among Scientific Highlights at AIDS 2024

Austin, TX

AIDS Healthcare Foundation (AHF) opened a new HIV clinic in Austin, Texas, that provides comprehensive care, including HIV testing, treatment, medical services, a pharmacy and services related to sexually transmitted infections (STIs), reports Fox 7. Austin Mayor Kirk Watson joined other local and state officials at the Friday ribbon cutting....

HIV Health Care Center Opens in Austin, Texas [VIDEO]

Antiretroviral therapy (ART) has been a game-changer for people with HIV. But HIV is skilled at “hiding” and can reappear in the blood stream shortly after ART is stopped. That’s why NIAID and partners are investigating strategies to completely clear HIV from a person’s body, effectively curing them, or to reduce it to levels that can be suppressed by their own immune systems.

Broadly Neutralizing Antibodies Evaluated in Many HIV Cure Strategies

Indiana State

Eighteen people living with HIV in Indiana were arrested between 2001 and 2019 for donating plasma, though, thanks to effective screening methods, none of them posed a risk of transmitting the virus, found a new report by the Williams Institute. The Williams Institute is a research center focusing on law...

People With HIV Have Been Arrested in Indiana for Donating Plasma

Miami, FL

Lamar McMullen of Miami is positively evangelical about long-acting injectables for HIV treatment. Currently, only one such medication is approved for injection every other month; others in the pipeline are intended to last even longer. Since giving up his once-a-day pill for a long-acting injectable, McMullen has been pleased with the results.

Getting Comfortable With Long-Acting Injectables

Los Angeles, CA

The Wall Las Memorias (TWLM), which provides health and wellness services to Latino, LGBTQ and other underserved populations, hosted a grand opening for its new Downtown Los Angeles (DTLA) Hub with a ribbon-cutting ceremony and open house. The new office is the group’s third and its second in downtown Los...

The Wall Las Memorias Opens a New Health and HIV Center in Downtown Los Angeles

Long-acting injectable cabotegravir (CAB-LA) was safe and well tolerated as HIV pre-exposure prophylaxis (PrEP) before and during pregnancy in the follow-up phase of a global study among cisgender women. The analysis of outcomes from more than 300 pregnancies and infants will be presented at the 2024 International AIDS Conference (AIDS 2024) in Munich, Germany.

Long-Acting Injectable Cabotegravir for HIV Prevention is Safe in Pregnancy

Strong bones help maintain mobility and enhance quality of life. People with HIV are more prone to bone loss and fractures, but you can take steps to improve bone health. Bone is living tissue largely made up of minerals and collagen. Cells called osteoblasts continually add new bone tissue, while osteoclasts dissolve old bone. As people age, bone resorption starts to outpace bone formation, and bone mass naturally declines. Osteopenia is an earlier stage of bone loss, which can progress to osteoporosis.

HIV and Your Bones

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Emily Standley Allard

Marriage is a significant life decision that requires extreme commitment, understanding, devotion and a heck of a lot of compromise. While many people dream of a lifelong partnership, others find the concept of marriage challenging. Astrology offers insights into personality traits and behaviors, suggesting that certain zodiac signs might face more difficulties in maintaining a traditional marital relationship. This article explores the five zodiac signs that are often considered less suited for marriage due to their unique characteristics and tendencies when it comes to lifelong commitment.

The 5 Zodiac Signs Not Meant for Matrimony

A Year of Hepatitis Advances to Mark World Hepatitis Day. Viral hepatitis affects the lives of about one in twenty people in the world, resulting in over a million deaths each year. NIAID is working on many ways to prevent and treat the different types of hepatitis, including the development of vaccines and improved therapeutics and diagnostics.

NIAID Research to Eliminate the Threat of Viral Hepatitis Across the Globe

EBT-101, a CRISPR-based gene-editing therapy, was safe and well tolerated in an early study, but it did not prevent viral rebound in the first four participants who interrupted antiretroviral treatment, according to a report at the International AIDS Conference (#AIDS2024) in Munich. One person, however, did see a decline in his HIV reservoir, and viral rebound was delayed for four months.

CRISPR Gene Therapy Does Not Prevent HIV Rebound

HIV stigma in health care is real and harmful. Fortunately, health care providers can now take the antiviral drug Stigmavir to treat their stigma. Unfortunately, the drug is fictitious, but you can watch a real ad for it on YouTube. Casey House, an AIDS service provider in Toronto, created the...

Stigmavir to Treat HIV Stigma?

Cover: Long-term survivor Bishop Stacey S. Latimer shares his advice on aging with HIV. Inside: Twice-yearly PrEP for women; HIV and your bones. Plus: Mark S. King questions his life-long fixation on survival.

POZ September 2024

Lenacapavir (Sunlenca), Gilead Sciences’ twice-yearly capsid inhibitor, demonstrated 100% efficacy for HIV prevention in a large study of young cisgender women in Africa. Oral PrEP is highly effective for people who can take it consistently, but additional options are still needed for people who have difficulty using daily pills. The Phase III PURPOSE 1 trial enrolled more than 5,300 women in South Africa and Uganda. They were randomly assigned to receive injectable lenacapavir once every six months or the daily PrEP pills Descovy (tenofovir alafenamide/emtricitabine) or Truvada (tenofovir disoproxil fumarate/emtricitabine) in a 2:2:1 ratio. There were zero new infections in the lenacapavir group, 39 in the Descovy group and 16 in the Truvada group. All three PrEP methods were well tolerated, and no new safety concerns were identified. A parallel study (PURPOSE 2) is testing lenacapavir PrEP for cisgender and transgender men, trans women and nonbinary people in the United States and six other countries; results are expected in late 2024 or early 2025.

Prevention: Twice-Yearly PrEP

This episode of HIV unmuted introduces a new host and format for the award-winning IAS podcast. Our host, Juan Michael Porter II, the Senior Editor for TheBody/TheBodyPro, takes a deep dive with a single guest in an intimate conversation that gives the listener a glimpse of the guest – who they are and how they got into this work – and an understanding of their topic of expertise.

HIV Unmuted - The Game-Changing Research from AIDS 2024

Traditional vaccine approaches have not been able to prevent HIV, but researchers are exploring more sophisticated strategies. One novel approach, known as germline targeting, trains the immune system to produce broadly neutralizing antibodies (bnAbs) that target parts of the virus that don’t change much as it evolves. Only about 15% of people with HIV produce these bnAbs naturally, but most have rare immature B cells that have the capacity to do so. To overcome HIV’s ability to hide, scientists build immunogens, artificial constructs of viral proteins designed to provoke a robust immune response. A series of different primer and booster immunogens are used in a stepwise manner to encourage maturing B cells to produce bnAbs.

Novel HIV Vaccine Approaches

Tennessee State

Shelby County, TN

Memphis, TN

In recent years, reported HIV and syphilis cases have surged in Tennessee’s Shelby County, which encompasses Memphis, prompting a response from the Shelby County Health Department (SCHD), reports WREG-TV News Channel 3. According to the Tennessee Department of Health (THD), since 2018, HIV rates have increased by 36%, and...

Memphis Area Sees Spike in HIV Cases

People who start antiretroviral therapy (ART) during acute HIV infection experience a faster decline in the viral reservoir in CD4 T cells. Within days after infection, the virus inserts its genetic blueprints into the DNA of host cells and establishes a long-lasting reservoir that is unreachable by antiretro-virals. Using more than 500 blood samples from 67 people in the UCSF Treat Acute HIV cohort who started ART within 100 days after infection, researchers developed mathematical models of HIV dynamics and control. The models showed a biphasic decay of integrated proviral DNA out to one year. During the first phase, lasting up to five weeks, there was a steep decrease in intact HIV DNA, followed by a slower decline during the second phase. For every week ART was delayed, the half-life of intact proviral DNA was about 14 hours longer during the first phase and eight days longer during the second phase. While even very early treatment usually doesn’t prevent viral rebound after stopping anti-retrovirals, a smaller reservoir could improve prospects for a functional cure.

Cure: Smaller Reservoir

Over the past two years, a simple but baffling request has preceded most of my encounters with medical professionals: “Rate your pain on a scale of zero to 10.”. I trained as a physician and have asked patients the very same question thousands of times, so I think hard about how to quantify the sum of the sore hips, the prickly thighs, and the numbing, itchy pain near my left shoulder blade. I pause and then, mostly arbitrarily, choose a number. “Three or four?” I venture, knowing the real answer is long, complicated, and not measurable in this one-dimensional way.

Pain Doesn’t Belong on a Scale of Zero to 10

Kissimmee, FL

Akeena

One Dunkin’ Donuts location, known for its familiar aroma of coffee and donuts, found itself temporarily closed after a state inspection uncovered a few issues. Not all Dunkin’ locations are created equal. Take the one at 3745 Pleasant Hill Road in Kissimmee, for instance. This particular branch, despite its efforts to keep customers caffeinated and satisfied, has had its share of mixed reviews.

Florida's donut shop closed due serious violations after state inspection

NewsBreak

Here’s How Cities and Urban Settings Can Better Respond to HIV

Globally, 70% of people are projected to live in cities by 2050. Consequently, urban settings will play a vital role in addressing the HIV epidemic as...

Here’s How Cities and Urban Settings Can Better Respond to HIV

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