Los Angeles Angels at Seattle Mariners odds, picks and predictions

The Los Angeles Angels (44-57) and Seattle Mariners (53-50) wrap up a 3-game series Wednesday. First pitch from T-Mobile Park is scheduled for 3:40 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Angels vs. Mariners odds and make our expert MLB picks and predictions for the best bets.

Season series: Angels lead 5-4

The Angels posted a 5-1 victory Tuesday, winning the series from the Mariners regardless of Wednesday’s result. The Halos used a big 5-run 5th inning to back RHP Jose Soriano , who allowed just 1 ER on 3 hits and 3 walks with 5 K’s in 7 2/3 IP in a 100-pitch quality start.

The Mariners were error-prone, committing 2 miscues, including a throwing error by RHP Logan Gilbert . The righty allowed 5 runs, with just 1 ER, in what turned out to be a 92-pitch quality start.

The Seattle offense continues to struggle, scoring 2 or fewer runs in 6 of the past 7 outings. That includes 4 straight losses against the Angels, totaling just 5 runs in the past 4 meetings. The Under has connected in 6 of the past 7 outings. Seattle is 13-6-1 in the past 20 games at T-Mobile Park, too.

Angels at Mariners projected starters

RHP Griffin Canning vs. RHP Luis Castillo

Griffin (3-10, 5.20 ERA) makes his 21st start. He has a 1.42 WHIP, 3.2 BB/9 and 6.2 K/9 in 105 2/3 IP.

• Last start: Loss, 3 1/3 IP, 6 ER, 6 H (1 HR), 2 BB, 3 K in 13-3 road setback vs. Oakland A’s Friday
• 2024 road splits: 0-8, 6.31 ERA (45 2/3 IP, 32 ER), 1.34 WHIP, .271 opponents’ batting average (OBA), 12 BB, 33 K in 9 starts
• 2024 vs. Mariners: Loss, 6 2/3 IP, 1 ER, 4 H (1 solo HR), 1 BB, 4 K in 1 start, a 5-1 road defeat June 2
• Career vs. Mariners: 2-2, 2.97 ERA (33 1/3 IP, 11 ER), 1.05 WHIP, 10.3 K/9 in 6 starts

Castillo (8-10, 3.55 ERA) makes his 22nd start. He has a 1.16 WHIP, 2.5 BB/9 and 8.6 K/9 in 124 1/3 IP.

• Last start: Loss, 7 IP, 3 ER, 6 H, 1 BB, 3 K in 3-0 home setback vs. Houston Astros Friday
• 2024 home splits: 5-4, 3.07 ERA (67 1/3 IP, 23 ER), 1.04 WHIP, .229 OBA, 12 BB, 69 K in 11 starts
• 2024 vs. Angels: Win, 6 IP, 0 ER, 4 H, 2 BB, 5 K in 1 start, an 11-0 road victory July 11
• Career vs. Angels: 5-1, 2.90 ERA (49 2/3 IP, 16 ER), 1.01 WHIP, 11.4 K/9 in 9 starts

Angels at Mariners odds

Provided by FanDuel Sportsbook ; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:10 a.m. ET.

• Moneyline (ML) : Angels +164 (bet $100 to win $164) | Mariners -196 (bet $196 to win $100)
• Run line (RL)/Against the spread (ATS) : Angels +1.5 (-140) | Mariners -1.5 (+116)
• Over/Under (O/U) : 7.5 (O: +100 | U: -122)

Angels at Mariners picks and predictions

Prediction

Mariners 5, Angels 2

Moneyline

The Mariners (-196) will cost you nearly 2 times your potential return. That’s quite risky anytime, but especially against an Angels (+164) side which has been the kryptonite of Seattle lately.

Canning has been awful, however, especially on the road, losing all 8 decisions away from home.

PASS , and look to the run line instead.

Run line/Against the spread

The MARINERS -1.5 ( +116 ) are a solid play at plus-money behind the veteran Castillo.

The M’s have managed just 1 win in the previous 8 outings. While Seattle has 6 wins since July 4, it has won 5 of those outings by 2 or more runs. If you like the Mariners to win, take them to cover the run line, too.

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Over/Under

UNDER 7.5 ( -122 ) is worth playing lightly, but go with a half-unit play at best.

The Under has hit at a 6-1 pace in the past 7 games for the Mariners, and that includes an Under result in the first 2 meetings in this series.

The Under connected Tuesday, and the total has ended up going low in 4 straight meetings between these AL West rivals. The Under is also 5-1 in the past 6 home starts for Castillo, including a 5-1 home win June 2 against the Angels.

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