Northern Illinois at Notre Dame odds, picks and predictions

The Northern Illinois Huskies (1-0) and Notre Dame Fighting Irish (1-0) meet Saturday. Kickoff from Notre Dame Stadium is set for 3:30 p.m. ET (NBC/Peacock). Below, we analyze FanDuel Sportsbook’s lines around the Northern Illinois vs. Notre Dame odds, and make our expert college football picks and predictions.

Northern Illinois stomped the Western Illinois Leathernecks 54-14 Saturday while covering as a 35.5-point favorite. QB Ethan Hampton completed a remarkable 18 of 20 passes for 328 yards and 5 TDs in the win. The Huskies totaled 706 yards of offense.

Notre Dame, which is No. 7 in the US LBM Coaches Poll, beat the No. 20 Texas A&M Aggies 23-13 Saturday while covering as a 3-point underdog. The Irish forced 2 turnovers and committed none themselves. Notre Dame scored 10 unanswered points in the final 2 minutes of the game to break a 13-13 tie.

– US LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

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Northern Illinois at Notre Dame odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 10:05 a.m. ET.

• Moneyline (ML): Northern Illinois +2000 (bet $100 to win $2,000) | Notre Dame -7000 (bet $7,000 to win $100)
• Against the spread (ATS): Northern Illinois +27.5 (-106) | Notre Dame -27.5 (-114)
• Over/Under (O/U): 44.5 (O: -115 | U: -105)

Northern Illinois at Notre Dame picks and predictions

Prediction

Notre Dame 42, Northern Illinois 10

PASS.

Notre Dame will come away with the win as a -7000 favorite, but this line is set far too heavily to risk betting on. Bet the spread and/or O/U instead.

BET NOTRE DAME -27.5 (-114).

Notre Dame is the far better and more proven team, and its defense will make life very difficult for NIU. Look for the Fighting Irish to dominate the Huskies, as they are riding hot after picking up a big win in their season opener.

This bet is slightly risky just because of the potential potency of NIU’s offense.

BET OVER 44.5 (-115).

Northern Illinois is a team that is led by its offense, and while it will not see as much success vs. the Irish, the Huskies still have the potential to put up points. Notre Dame has a very capable offense itself, so the Over is a safe bet here.

Notre Dame has a very good defense that will make life tough on this Huskies offense, but with a total as low as 44.5, the Over is still very attainable, as the Irish should be able to get whatever they want offensively.

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