Cubs vs. Blue Jays odds, line, score prediction, start time: 2024 MLB picks, Aug. 16 best bets by proven model

Teams trending in opposite directions of late meet in an interleague matchup when the Toronto Blue Jays battle the Chicago Cubs on Friday afternoon. Toronto has won three in a row, while Chicago has dropped three straight. The Blue Jays (57-64), fifth in the American League East, have won six of their last 10 games. The Cubs (59-63), fourth in the National League Central, are 26-28 during the day. The Blue Jays lead the all-time series 11-10, but the Cubs have a 4-2 edge in games at Wrigley Field.

First pitch from Wrigley Field in Chicago is set for 2:20 p.m. ET. Chicago is a –114 favorite on the money line (risk $114 to win $100) in the latest Blue Jays vs. Cubs odds from SportsLine consensus, while the total number of runs Vegas thinks will be scored, or the over/under, is 10. Before making any Blue Jays vs. Cubs picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer simulation model .

The SportsLine Projection Model simulates every MLB game 10,000 times. Entering Week 21 of the MLB season, it's on a 25-13 roll on top-rated run-line picks (+732) that dates back to last season. Anybody following has seen strong returns.

Now, the model has set its sights on Blue Jays vs. Cubs and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks . Now, here are several MLB odds and betting lines for Blue Jays vs. Cubs:

• Blue Jays vs. Cubs money line: Toronto -105, Chicago -114
• Blue Jays vs. Cubs over/under: 10 runs
• Blue Jays vs. Cubs run line: Toronto -1.5 (+138)
• TOR: The Blue Jays have covered the run line in 27 of their last 40 away games (+12.10 units)
• CHC: The Cubs have hit the game total under in 56 of their last 103 games (+8.70 units)
• Blue Jays vs. Cubs picks: See picks at SportsLine
  

Why you should back the Cubs

Chicago is expected to send right-hander Kyle Hendricks (3-10, 6.60 ERA) to the mound. Hendricks has pitched well of late, allowing three or fewer earned runs in 12 of his last 14 appearances. In his last outing, a 3-0 loss to the Minnesota Twins , Hendricks pitched six innings, allowing five hits, two runs – both earned – with one walk and five strikeouts. In a 5-1 win at St. Louis on July 12, he pitched seven shutout innings, allowing just five hits and one walk, while striking out three.

Center fielder Cody Bellinger is among Chicago's top hitters. In 92 games this season, he is hitting .276 with 16 doubles, one triple, 12 homers and 46 RBI. In a 7-6 win over the Chicago White Sox on Aug. 9, he was 3-for-4 with a homer, two RBI and two runs scored. He has hits in seven of the past 10 games. In six career games against the Blue Jays, he is batting .318 with three doubles, one homer and six RBI. See which team to pick here .

Why you should back the Blue Jays

Right-hander Yariel Rodriguez (1-5, 3.60 ERA) will start for Toronto. In 12 starts, Rodriguez has logged 50 innings pitched, allowing 40 hits, 20 earned runs and 25 walks, while striking out 52. The rookie pitched well in his last outing but suffered a 1-0 setback to the Oakland Athletics . In that game, he pitched 5.2 innings, allowing five hits, one earned run and one walk, while striking out five.

Among the Blue Jays' top hitters is first baseman Vladimir Guerrero Jr. The 25-year-old is hitting .323 in 120 games, including 32 doubles, one triple, 25 homers and 80 RBI. He destroyed Los Angeles Angels pitching this week, going 6-for-14 with two homers and four RBI in a three-game series that finished up on Wednesday. He also had three hits with a double, triple, homer and four RBI in a 7-6 win over the Baltimore Orioles on Aug. 8. See which team to pick here .

How to make Blue Jays vs. Cubs picks

SportsLine's model is leaning under on the run total and it says one side of the money line has all the value. You can only get the MLB model's picks at SportsLine .

So who wins Blue Jays vs. Cubs, and which side of the moneyline has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that is on a 25-13 roll on its MLB picks , and find out.