The burglars hit the celebrity couple's guest house, but did not breach the main house.
Nobody was home at the time, and it is not believed they were targeted in the incident, according to officials.
Police have not arrested any suspects as of Monday.
The suspects are believed to have been part of the ongoing crews that have been hitting high end neighborhoods indiscriminately for the last few years, the law enforcement sources said.
A spokesperson for Hanks did not immediately respond to a request for comment from ABC News.
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