Cleveland Guardians at Minnesota Twins odds, picks and predictions

The Cleveland Guardians (67-49) and Minnesota Twins (65-50) play the 3rd contest of a 4-game series Saturday. First pitch from Target Field is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Guardians vs. Twins odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 5-2

Cleveland entered Friday’s doubleheader with a 3½-game lead in the AL Central, but it was trimmed to just 1½ games after Minnesota swept the twin bill. The Guardians had won the first 5 meetings vs. the Twins this season, but Minnesota won 4-2 in Game 1 and 6-3 in Game 2.

The Guardians have picked a terrible time for a season-high 7-game losing skid. The Over has cashed in 7 of the past 9 outings.

The Twins have caught fire, winning 7 of the past 9 contests, with the Over going 6-2-1 during the span. The offense is averaging 6.2 runs per game during the 9-game span.

Guardians at Twins projected starters

RHP Gavin Williams vs. RHP Simeon Woods Richardson

Williams (1-4, 4.91 ERA) makes his 8th start. He has a 1.48 WHIP, 3.6 BB/9 and 10.6 K/9 in 33 innings.

• Last start: Loss, 4 IP, 6 ER, 8 H (2 HR), 2 BB, 8 K in 9-5 home setback vs. Baltimore Orioles Sunday
• 2024 road splits: 1-0, 0.59 ERA (15 1/3 IP, 1 ER), 0.91 WHIP, .164 opponents’ batting average (OBA), 5 BB, 15 K in 3 starts
• Career vs. Twins: 1-0, 1.50 ERA (6 IP, 1 ER), 1 H, 0 HR, 5 BB, 4 K in 2 starts

Woods Richardson (3-2, 3.87 ERA) makes his 20th start. He has a 1.23 WHIP, 2.9 BB/9 and 7.9 K/9 in 95 1/3 innings.

• Last start: No-decision, 4 IP, 3 ER, 6 H, 3 BB, 6 K in 13-7 home victory vs. Chicago White Sox Sunday

• 2024 home splits: 1-0, 3.40 ERA (47 2/3 IP, 18 ER), 1.11 WHIP, .202 OBA, 18 BB, 47 K in 9 starts
• Career vs. Guardians: No-decision, 5 1/3 IP, 1 ER, 4 H, 0 BB, 2 K in 1 start, a 3-2 road loss May 17

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Guardians at Twins odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:50 a.m. ET.

• Moneyline (ML): Guardians +100 (bet $100 to win $100) | Twins -118 (bet $118 to win $100)
• Run line (RL)/Against the spread (ATS): Guardians -1.5 (+164) | Twins +1.5 (-200)
• Over/Under (O/U): 8.5 (O: -110 | U: -110)

Guardians at Twins picks and predictions

Prediction

Twins 5, Guardians 4

The TWINS (-118) are a solid play as small favorites in Game 3 of this crucial series in the AL Central.

The Guardians (+100) are skidding hard, dropping a season-high 7 games, and all 7 of the losses have come as underdogs.

Minnesota has won 7 of the past 8 games when favored and 6 in a row at home.

The Twins +1.5 (-200) will cost you 2 times your potential return, and that’s way too expensive if you require a little bit of insurance.

If you like Minnesota, just play it straight up.

AVOID.

OVER 8.5 (-110) is the lean, but go with a half-unit play at best.

The Over/Under split in Friday’s double dip. The Over has cashed at a 6-2-1 clip in the past 9 games for the Twins. The Over is 4-1-1 in the past 6 home outings for Minnesota, too.

The Guardians have cashed high at a 7-2 clip in the past 9 games, but be careful, as the Under is 8-2 in the past 10 outings on the road.

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